Filtyp
Purpose: The FANCM c.5101C>T nonsense mutation was previously found to associate with breast cancer in the Finnish population, especially among triple-negative cases. Here, we studied the prevalence of three other FANCM variants: c.5791C>T, which has been reported to predispose to familial breast cancer, and the c.4025_4026delCT and c.5293dupA variants recently identified in Finnish cancer patient
Background: Human milk is a complex fluid comprised of myriad substances, with one of the most abundant substances being a group of complex carbohydrates referred to as human milk oligosaccharides (HMOs). There has been some evidence that HMO profiles differ in populations, but few studies have rigorously explored this variability. Objectives: We tested the hypothesis that HMO profiles differ in d
Scand J Caring Sci; 2009 Utilization of medical healthcare among people receiving long-term care at home or in special accommodation Aim: To investigate the utilization of medical healthcare, hospital care and outpatient care, during a 1-year period in relation to informal care, multimorbidity, functional status and health complaints and to long-term care at home or in special accommodation among
Abstract Background. Dosimetry in radionuclide therapy estimates delivered absorbed doses to tumours and ensures that absorbed dose levels to normal organs are below tolerance levels. One procedure is to determine time-activity curves in volumes-of-interests from which the absorbed dose is estimated using SPECT with appropriate corrections for attenuation, scatter and collimator response. From cor
Popular Abstract in English The aim of this thesis is to investigate the evolution of new technology-based firms (NTBFs) based on solid empirical material for the Swedish economy. The focus on this thesis is exploring the role of acquisition by incumbent firms in the evolution of NTBFs. The findings of this thesis show that selection is a core feature in the evolution of NTBFs. NTBFs experience a The aim of this thesis is to explore the evolution of new technology-based firms (NTBFs) based on solid empirical material for the Swedish economy. NTBFs are argued to be one important type of entrepreneurial firms that contribute to technology change, knowledge spillovers, and economic growth. However, our knowledge concerning how NTBFs exert their technological and economic influences is far fro
This thesis is concerned with the ways in which justice is dispensed in Swedish courts in cases concerning anti-Muslim violence. Based on material accessed through the Swedish National Board for Crime Prevention and classified as Islamophobic hate crimes, the judicial treatment of cases that may involve racism is analysed. An aim is to explore how different laws against racism in the Swedish legal
Background: Alloreactive memory T cells are a major obstacle to transplantation acceptance due to their capacity for accelerated rejection. Methods: C57BL/6 mice that had rejected BALB/c skin grafts 4 weeks earlier were used as recipients. The recipient mice were treated with anti-CD154/LFA-1 with or without anti-CD70 during the primary skin transplantation and anti-CD154/LFA-1 or not during the s
Lagen (1915:218) om avtal och andra rättshandlingar på förmögenhetsrättens område, AvtL och Internationella köplagen eller United Nations Convention on Contracts for the International Sale of Goods, CISG, innehåller båda bestämmelser om ingående av avtal som bygger på en anbud-acceptmodell. Även om båda regelverken har samma grundstruktur, skiljer de sig åt i några avseenden, särskilt ifråga om möLagen (1915:218) om avtal och andra rättshandlingar på förmögenhetsrättens område, AvtL, and the United Nations Convention on Contracts for the International Sale of Goods, CISG, both contain provisions on the conclusion of contracts based on an offer-acceptance model. Although both legal systems have the same basic structure, they differ in some aspects, especially regarding the possibility to re
Radongas is radioactive and dangerous for the human health. The radiation can cause serious diseases such as lung cancer. "Good built environment" is one of the 16 national environmental goals in Sweden which says that before year 2020 there must be no dwellings with radon concentrations over 200 Bq / m3 air. The environmental governance has on several occasions before attempted to ident
This thesis investigates how digitalisation influences the strategy of German hospitals via the provision of a holistic overview of potential digital solutions and how they can be used to enhance the hospitals’ core processes. Scrutinising the current utilisation, barriers to implementation and the effect that software-based systems have on the hospital’s strategy are at the study’s core. Here, a
There is a strong need to replace animal-based experiments with in vitro alternatives. Mutz-3, a myeloid cell line, has been successfully used to investigate skin sensitization. A problem with in vitro assays, not only affecting Mutz-3, is the use of Fetal Bovine Serum for cell cultivation, as it is a serum supplement which is not fully defined, and it introduces variability in cell-based experime
Plant-pollinator interactions are considered one of the primary factors driving the large diversity in floral traits. Adaptive floral trait diversification occurs when different pollinators show preference for different floral phenotypes imposing selection on, and potentially generating local adaptation, of floral traits in populations that interact with different insect communities. Plants in gen
I have always been curious about the effects architecture and the built environment have on us. The special atmosphere and the ability to arouse a sense of safety and calmness, but also the negative feelings certain spaces can evoke. Which architectural elements contribute to the way we perceive a space and more importantly, does the built environment not only affect our emotions but also our ment
Abstract: Background: Dementia is a global public health concern as it causes high dependency of the patients with Dementia (PwD) on their families and the community. Dementia is an irreversible neurodegenerative disorder for the elderly often associated with many comorbidities such as hypertension, diabetes, kidney diseases, etc. which require different medications for treatment. The use of A
The Laser Interferometer Space Antenna (LISA) is a space borne gravitational wave detec- tor set to launch in 2034, with the objective of detecting and studying the Gravitational Waves (GWs) of our universe. So far, ground-based detectors such as the Laser Interferometer Gravitational-Wave Observatory (LIGO) have been successful in detecting GWs, but the limitations of ground based detectors is wh
In the government's report Arkiv för alla –nu och i framtiden from 2002, one of the goals was to increase public understanding and interest of the archives as a source of information and knowledge. To do this, the report concludes that the archives have to become more visible and more accessible to the public. The aim of this master's thesis is to examine how the archive staffs in the Ci
One of the leading causes of biodiversity loss and species communities’ alteration is land-use change for agricultural purposes. Land-use may affect pollinators directly or indirectly via the plant communities. A better understanding of plant community and pollinators interactions can be important to comprehend the potential for management to support pollinating insects in different habitats. This
Habitat specialists are particularly vulnerable to habitat loss and disturbances because they are adapted to a narrow range of ecological conditions and food sources. The lesser spotted woodpecker is closely linked to attributes of deciduous forests that are negatively affected by intensive management. This is because it is specialised in foraging on wood-living insect larvae found in thin dead br
Sex-limited polymorphism is an interesting evolutionary phenomenon, which is widespread across organisms. Studying ultimate mechanisms that result in the evolution of sex-limited polymorphism can provide a window into how natural and/or sexual selection can result in the evolution of complex phenotypes. Here, I use butterflies from the tribe Polyommatini to study the evolutionary mode and tempo of
