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Factor VIII (FVIII)-bypassing agents have complex modes of action but all control bleeding in inhibitor patients by triggering the generation of thrombin. No routine test is available for monitoring this therapy in patients with inhibitors against FVIII. We present an assay that records FEIBA- or FVIIa- mediated changes in thrombin generation (TG) in FVIII inhibitor plasma samples. In plasma sampl

This presentation builds on several ethnographic fieldworks (2011-2015) in southern Sweden on people who have Palestinian background as well as my on-going informal involvement with Palestinian networks. The field material includes about 35 qualitative interviews, numerous informal discussions and participant observations of political events (mostly demonstrations and lectures) and people’s daily This presentation builds on several ethnographic fieldworks (2011-2015) in southern Sweden on people who have Palestinian background as well as my on-going informal involvement with Palestinian networks. The field material includes about 35 qualitative interviews, numerous informal discussions and participant observations of political events (mostly demonstrations and lectures) and people’s daily

Inom ett par år kommer det nya materialforskningscentret ESS, The European Spallation Source, att stå färdigbyggt. Det kommer då vara det mest avancerade forskningsinstitutet i sitt slag och leverera upp till 30 gånger fler neutroner än någon annan neutronkälla i världen. En av de viktigaste komponenterna på ESS är det s.k. strålmålet som består av nästan 7000 bitar av det metalliska grundämnet voThe European Spallation Source (ESS), which is currently under construction in Lund, will use pure tungsten as the spallation neutron target. The tungsten will be irradiated by a 2 GeV proton beam, pulsed at a repetition rate of 14 Hz. Each pulse will deposit 357 kJ in the tungsten causing an instantaneous temperature rise of approximately 100 °C, during the 2.86 ms pulse duration. The target is w

According to the Swedish Enforcement Code a debtor is presumed to be the sole owner of movable property which is possessed jointly with a spouse or domestic partner. In my thesis, I investigate this statutory presumption of ownership from a family law perspective. The applicability of the statutory presumption as well as its legal repercussions are determined by family law. It is therefore surprisAccording to the Swedish Enforcement Code a debtor is presumed to be the sole owner of movable property which is possessed jointly with a spouse or domestic partner. In my thesis, I investigate this statutory presumption of ownership from a family law perspective. The applicability of the statutory presumption as well as its legal repercussions are determined by family law. It is therefore surpris

BACKGROUND: Despite much debate, there is little evidence on consequences of consent procedures for residual tissue use. Here, we investigated these consequences for the availability of residual tissue for medical research, clinical practice, and patient informedness.METHODS: We conducted a randomised clinical trial with three arms in six hospitals. Participants, patients from whom tissue had been

Trisomy 7 as the single chromosome aberration has been found in a variety of neoplasms and in normal tissue in the proximity of tumors, as well as in non-neoplastic lesions. Recently, we described a nonrandom pattern of chromosome aberrations, in particular, a gain of chromosome 7, in synovia, cartilage, and osteophytes from patients with osteoarthritis. To study the clonal origin of trisomy 7 in

HAMLET is the first member of a new family of tumoricidal protein-lipid complexes that kill cancer cells broadly, while sparing healthy, differentiated cells. Many and diverse tumor cell types are sensitive to the lethal effect, suggesting that HAMLET identifies and activates conserved death pathways in cancer cells. Here, we investigated the molecular basis for the difference in sensitivity betwe

To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic disease risk, we conducted a genome-wide association meta-analysis of body fat percentage (BF%) in up to 100,716 individuals. Twelve loci reached genome-wide significance (P<5 × 10(-8)), of which eight were previously associated with increased overall adiposity (BMI, BF%) and four (in or near COBLL1/GR

Aim and objectives: To explore nurses’ articulations of support and communication regarding sexual health with patients.Background: Sexual health is adversely effected by cancer and various oncological treatments. Patients’ often have the experience that health-care professionals do not talk about sexual health.Method: Semi-structured interviews were conducted with seven nurses in Southern Sweden.Aim and objectives: To explore nurses' articulations of support and communication regarding sexual health with patients. Background: Sexual health is adversely effected by cancer and various oncological treatments. Patients' often have the experience that healthcare professionals do not talk about sexual health. Method: Semi-structured interviews were conducted with seven nurses in Southern Sweden

The ability of intrahippocampal grafts of fetal septal-diagonal band tissue, rich in developing cholinergic neurons, to ameliorate cognitive impairments induced by bilateral fimbria-fornix transections in rats was examined in three experiments using the Morris water-maze to test different aspects of spatial memory. Experiment 1. Rats with fimbriafornix lesions received either septal cell suspensio

Surface heparinization of central venous catheters has earlier been shown to reduce the frequency of bacterial colonization and septicaemia. The present study was undertaken to investigate the benefit of surface heparinization of external ventricular drainage (EVD) catheters in relation to bacterial colonization, as measured by bacterial growth and examination by a 16S-rRNA PCR assay, of catheters

Although advances in cardiopulmonary resuscitation have improved survival from cardiac arrest (CA), neurologic injury persists and impaired mitochondrial bioenergetics may be critical for targeted neuroresuscitation. The authors sought to determine if excellent cardiopulmonary resuscitation and postresuscitation care and good traditional survival rates result in persistently disordered cerebral mi

Danielsson, F. 2023. Rya gamla kyrka: A study about the relation between landscape and church in Rya parish. Medieval churches have been a key part of the research field of historical archaeology in Lund since its beginning. In recent years there have been an increasing interest in studying the relationship between early church construction and the landscape in which they were formed. This study a

Bilingualism has become increasingly prevalent globally, with about half of the world's population being bilingual by 2012. This growing trend has prompted cognitive research to explore the effects of bilingualism on executive functions. The Bilingual Advantage (BA) theory posits that bilingual individuals experience enhanced cognitive abilities due to their practice in managing multiple langu

This project has developed from the site and building conditions in an area of central Boden, a town in the inland north of Sweden. In post-war times, the city grew thanks to the military and regional hospital resulting in the development of the site Prästholmen that was realized true to the modernistic ideal of the time. Since then, Boden together with its inland neighbours, have struggled agai

Reducing the ecological footprint and achieving environmental sustainability is regarded as one of the main goals of the world in recent decades. To achieve these goals, some practices in people’s life should be changed. As an essential part of human needs, food consumption is one of the practices that significantly impact environmental sustainability. In the last few decades, modern technologies,

In this paper I explore how the US-American competitive cooking show MasterChef Junior assigns its 8 to 13- year-old contestants with a notion of strength. In the first part of the paper I will demonstrate how the show constructs different categories of knowledge and values of food and food practices which I will define as soft and hard culinary capital. I will describe how food is presented, how

Zinc oxide nanoparticles (ZnO NPs) are often used in sunscreen and other cosmetic products with sun protection. They are also candidate to be used for various biological applications such as drug delivery, or in material science in for example solar cells. ZnO NPs are produced as liquid suspensions but also as dry powders, which increases the risk of exposure via the air. In this master’s thesis,