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Popular Abstract in Swedish Alla levande celler har förmåga att känna av och på olika sätt anpassa sig till sin omgivning, antingen de ensamma utgör en hel organism eller är en av många miljarder celler i ett stort djur. Varje enskild cell kan bara ta emot en begränsat mängd olika sorters signaler och bara reagera på ett likaledes begränsat antal sätt. Den en- eller fåcelliga organismen är därmed The G protein-coupled receptors form one of the largest families of proteins involved in signalling between cells. It contains receptors for molecules as diverse as biogenic amines, glycoproteins and enzymes. The manuscripts included in this thesis together describe the initial characterisation of a previously unknown receptor of this class. A DNA fragment was cloned from a mouse genomic library.

Popular Abstract in Swedish FN:s barnkonvention formulerar barns och ungas behov i termer av mänskliga rättigheter. Sverige ratificerade konventionen efter ett beslut i riksdagen den 21 juni 1990, utan att reservera sig på någon punkt. Konventionens budskap kan sammanfattas i tre ord: Barn skall respekteras. Vuxna skall se barnet, sträva efter att förstå det och vidta åtgärder som bedöms vara tillThe main purpose was to investigate children's participation in the decision-making processes in health care. Twenty-four children (0-18 år)admitted to hospital, their parents, and the staff present were observed during totally 135 hours in order to (i) identify the children's needs, (ii) their participation in the decision-making processes, and (iii) their parents' participation. Twenty-six child

Popular Abstract in Swedish Extracellulär matrix är namnet på det molekylära nätverk vilket finns mellan celler i flercelliga organismer. Det består av socker och proteiner organiserade i olika vävnadsspecifika nätverk. Två huvudformer finns, basalmembran och interstitiell extracellulär matrix. Basalmembran ligger som en tunn filt under epitel- och endotelceller, runt fettväv, muskler och periferaBasement membranes are sheet like structures underlying epithelial, endothelial, adipocytes, muscle and peripheral nerve cells. Laminins are an important family of basement membrane proteins implicated in various biological functions through their interactions with cell surface receptors. Laminins are trimers composed of a, b and g chains. Integrins, dystroglycan and other transmembrane glycoprote

It is known that human errors are the cause of most structural failures. Extreme loads or material deficiencies are normally of secondary importance. This Project has studied the human factor in the design phase; how subjective decisions, individual knowledge and the use of advance tools and codes affect structural safety and structural design. 17 Swedish structural engineers from the house-buildi

Lewis' concept of admissibility was introduced as an integral part of his famous Principal Principle; the principle that initial rational/reasonable belief should conform to objective chance unless there is evidence to the contrary. At that time Lewis offered only the rough and ready characterisation that evidence not to the contrary of such dependence is admissible. This, together with some suffi

Apart from providing some new experimental data the paper reviews previous investigations concerning fluctuating lift acting on a stationary circular cylinder in cross-flow. In particular, effects of Reynolds number in the nominal case of an infinitely long and nonconfined cylinder in a smooth oncoming flow are discussed. The Reynolds number range covered is from about Re = 47 to 2 x 10(5), i.e.,

The conditions for successful epitaxial lateral overgrowth of W patterns by InAs using low-pressure metalorganic vapour phase epitaxy were studied. The substrates used were InAs (0 0 1) wafers and the range of growth temperatures between 500 and 600 degrees C. The selective growth was investigated as a function of the V/III-ratio on W-ring test structures and wires oriented in different directions

A multi-stage assembly network is considered. A number of end items should be delivered at a certain time. Otherwise a delay cost is incurred. End items and components that are delivered before they are needed will cause holding costs. All operation times are independent stochastic variables. The objective is to choose starting times for different operations in order to minimize the total expected

We provide evidence that the human papillomavirus (HPV) E2 protein regulates HPV late gene expression. High levels of E2 caused a read-through at the early polyadenylation signal pAE into the late region of the HPV genome, thereby inducing expression of L1 and L2 mRNAs. This is a conserved property of E2 of both mucosal and cutaneous HPV types. Induction could be reversed by high levels of HPV-16

Projects in the space domain are extremely complex and often characterized as being “one-off”, which makes it very difficult to make good predictions on future developments. Furthermore, space projects are also associated with state-of-the-art technology, high costs and long development time. Risks are therefore a threat to project success because they may have negative effects on the project cost

Ett av de svåraste momenten för en domare är hur de ska värdera en muntlig utsaga. Vid sexualbrott är det vanligt förekommande att en utsaga är den största bevisningen, det är därför av största vikt att en utsaga värderas på ett objektivt och godtagbart sätt. I Sverige finns det ingen lagreglering om hur en bevisvärdering ska gå till. För att rättssäkerheten inte helt ska försvinna finns det riktlOne of the most difficult moments of a judge is how to evaluate an oral statement. When dealing with sex crimes the oral statement is usually the biggest evidence, it is therefore important that an oral statement is valued in an objective and acceptable manner. In Sweden, there is no legal regulation on how an evaluation on oral statements should work. There are guidelines for the evaluation of or

To enhance the performance of gas turbine engines, high top-cycle temperatures are desired. However, the temperature is limited by current materials. To achieve the higher performance, and meanwhile maintain the metal temperatures of the combustors, vanes and blades below the allowable limits, sophisticated cooling techniques, such as impingement cooling, film cooling and convective internal cooli

Demensvården har behov av att hitta alternativa behandlingsformer som kan bidra till ökad livskvalité för personer med demens. Denna interventionsstudie där kvantitativ metod användes, syftade till att se om bildskapande verksamhet hade någon påverkan på livskvalité, kognitiv och funktionell förmåga samt psykiska symtom. Totalt 19 personer med demens som var beroende av vård och omsorg valdes ut p

I en strävan efter att göra brottsbekämpningen mer effektiv har miljösanktionsavgifter kommit att bli allt vanligare på miljörättens område. Kravet på effektivitet är inte alltid lätt att förena med kravet på rättssäkerhet. Sanktionsavgifternas framväxt som respons på den ökade brottsligheten riskerar att leda till att tidigare straffrättsliga principer och rättssäkerhetsgarantier utvidgas allt meIn an attempt to streamline law enforcement, the use of environmental sanction charges has become more and more common within the area of Swedish environmental law. To obtain efficiency without neglecting general principles of fairness and legal certainty, the rule of law, is however easier said than done. The extended use of environmental sanction charges to prevent crimes may even jeopardize for

Grassroots Innovations (GI) have became a successful mechanism developed by the associative capacity of people that seek to provide solutions to their own problems relying on the values of solidarity and reciprocity while striving for social transformation (Smith and Seyfang, 2007; Seyfang and Haxeltine, 2012). However, GI still endure three challenges, namely: adaptation vs. transformation, local

OBJECTIVE: To determine the efficacy and safety of low carbohydrate diets (LCDs) and very low carbohydrate diets (VLCDs) for people with type 2 diabetes. DESIGN: Systematic review and meta-analysis. DATA SOURCES: Searches of CENTRAL, Medline, Embase, CINAHL, CAB, and grey literature sources from inception to 25 August 2020. STUDY SELECTION: Randomized clinical trials evaluating LCDs (<130 g/day or

Data from NASA's Kepler space telescope, which searches for exoplanets via the transit method, produced 1108 new planetary candidates in 2013 with a total of 91% being smaller than Neptune in size. These were mostly super-Earths, terrestial planets between Earth and Neptune in size, with orbits around 10 days. In order for any theory of planet formation to be valid it must be able to account

BACKGROUND: Aspergillus fumigatus is the most common filamentous fungus isolated from the airways of people with cystic fibrosis (CF). The aim of this study was to investigate how chronic A. fumigatus colonization affects lung function in people with CF, to identify risk factors for colonization, and to evaluate antifungal treatment of asymptomatic Aspergillus colonization.METHODS: Data from 2014-