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The precision of an eye-tracker is critical to the correct identification of eye movements and their properties. To measure a system’s precision, artificial eyes (AEs) are often used, to exclude eye movements influencing the measurements. A possible issue, however, is that it is virtually impossible to construct AEs with sufficient complexity to fully represent the human eye. To examine the conseq

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Objective: Adult-onset IgA vasculitis (Henoch-Schönlein) (IgAV) is a rare systemic vasculitis characterized by IgA1-dominant deposits. The treatment of adult-onset IgAV is controversial and is based on the combination of glucocorticoids and immunosuppressive agents, but many patients have refractory or relapsing disease despite treatment. Rituximab (RTX) is a B cell–depleting antibody of proven ef

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Evacuation times can be shortened in fire scenarios if people choose appropriate routes. Way-finding systems can be used to aid this process, thus their effectiveness needs to be evaluated. In the present study, the way-finding evacuation systems of the Future Circular Collider (FCC) of the European Organization for Nuclear Research (CERN) are investigated as its evacuation design presents several

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In recent years, as 6G wireless systems continue to develop, high-accuracy indoor localization has become increasingly important for future wireless systems. At the same time, reliable indoor positioning is needed by many location-aware applications, such as robotic navigation, emergency healthcare, and smart transportation. Since indoor wireless measurements can vary over time due to multipath pr

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Wind damage is one of the most economically and ecologically significant natural disturbances in European forests, yet the cloud cover that follows major storms routinely blocks optical satellite acquisitions for weeks, precisely when rapid damage mapping is most valuable. Synthetic aperture radar (SAR) circumvents this limitation through all-weather imaging, but pixel-level windthrow detection fr

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Therapeutic peptides are a fast-increasing segment in the pharmaceutical industry, and GLP-1 analogues stood for two out of the three most sold drugs last year, 2025. The most common production method of peptides is based on Merrifield’s discovery of solid-phase peptide synthesis (SPPS), which uses large volumes of hazardous chemicals like N,N-dimethylformamide (DMF), piperidine, and trifluoraceti

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Electricity demand in southern Sweden is expected to increase significantly in the coming decades. More electric cars, cleaner industries, and the phase-out of fossil fuels will require much larger amounts of electricity than today. At the same time, Skåne currently produces only part of the electricity it consumes and depends heavily on electricity imports from other regions and neighbouring coun

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Various devices rely on invasive biometric identifiers, such as voice and facial recognition, raising privacy concerns. Acoustic handclap control presents a privacy-preserving alternative for interaction with computers, as it does not capture speech or visual data. An analysis of the original implementation suggested that existing classifiers were influenced by environmental bias. With the objecti

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Most viruses undergo a maturation process from a weakly self-assembled, noninfectious particle to a stable, infectious virion. For herpesviruses, this maturation process resolves several conflicting requirements: (i) assembly must be driven by weak, reversible interactions between viral particle subunits to reduce errors and minimize the energy of self-assembly, and (ii) the viral particle must be

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Replacing fossil jet fuel with biojet fuel is an important step towards reducing greenhouse gas (GHG) emissions from aviation. To this end, Sweden has adopted a GHG mandate on jet fuel, complementing those on petrol and diesel. The GHG mandate on jet fuel requires a gradual reduction in the fuel’s GHG emissions to up to 27% by 2030. This paper estimates the potential production of biojet fuel in S

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Objective: The purpose of this study was to explore the feasibility to determine regional diagnostic reference levels (RDRLs) for paediatric conventional and CT examinations using the European guidelines and to compare RDRLs derived from weight and age groups, respectively. Methods: Data were collected from 31 hospitals in 4 countries, for 7 examination types for a total of 2978 patients. RDRLs we

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Small- and medium-sized enterprises (SMEs) have inherent characteristics, which require specific solutions for improving the sustainability performance of their operations. The purpose of this paper is to increase the knowledge on barriers and enablers for the adoption of sustainable manufacturing by manufacturing SMEs and to provide insights into what enablers can be used to overcome existing bar

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BACKGROUND: Despite much debate, there is little evidence on consequences of consent procedures for residual tissue use. Here, we investigated these consequences for the availability of residual tissue for medical research, clinical practice, and patient informedness.METHODS: We conducted a randomised clinical trial with three arms in six hospitals. Participants, patients from whom tissue had been

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BACKGROUND: Plasma biomarkers for Alzheimer's disease (AD) have broad potential as screening tools in primary care and disease-modifying trials. Detecting elevated amyloid-β (Aβ) pathology to support trial recruitment or initiating Aβ-targeting treatments would be of critical value. In this study, we aimed to examine the robustness of plasma biomarkers to detect elevated Aβ pathology at different

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Background: Mohs micrographic surgery (MMS) is a precise, tissue-sparing surgical technique that offers superior cure rates compared to traditional surgical excision. However, the degree of difficulty of MMS depends on many variables, and consequently, the number of surgical stages required for each case is quite unpredictable.Objectives: To identify risk factors for complicated MMS, defined as MM

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Mining is an economically-beneficial activity recognized as crucial in modern society since almost every aspect of our lives relies on minerals. However, intensive mining activities impose a severe strain on the water-energy nexus. In fact, mining ventures: i) need massive amount of water in various ore processing steps; ii) generate a huge amount of waste (tailings), generally transferred to tail

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We describe the outcome of a data challenge conducted as part of the Dark Machines (https://www.darkmachines.org) initiative and the Les Houches 2019 workshop on Physics at TeV colliders. The challenged aims to detect signals of new physics at the Large Hadron Collider (LHC) using unsupervised machine learning algorithms. First, we propose how an anomaly score could be implemented to define model-

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Our overall understanding of long-term climate dynamics is largely based on proxy data generated from archives such as ice cores, ocean sediments, tree rings, speleothems, and corals, whereas reconstructions of long-term changes in vegetation and associated climate during the Holocene are largely based on paleoecological records from peat and lake sequences, primarily pollen and plant macrofossil