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A system for interstitial photodynamic therapy is used in the treatment of thick skin tumors. The system allows simultaneous measurements of light fluence rate, sensitizer fluorescence, and tissue oxygen saturation by using the same fibers as for therapeutic light delivery. Results from ten tumor treatments using delta-aminolevulinic acid (ALA)-induced protoporphyrin IX show a significant, treatme
The present study examined the influences of the muscle contraction (MCP) and relaxation (MRP) phases, as well as systole and diastole, on the blood velocity profile and flow in the conduit artery at different dynamic muscle contraction forces. Eight healthy volunteers performed one-legged dynamic knee-extensor exercise at work rates of 5, 10, 20, 30, and 40 W at 60 contractions per minute. The ti
BACKGROUND: Positron emission tomography (PET) provides metabolic information of tissues in vivo. The purpose of this study was to assess the value of PET with 2-[(18) F] fluoro-2-deoxy-D-glucose (FDG) in prediction of therapy outcome (tumor response, survival, and locoregional control) in locally advanced HNSCC. METHODS: Between 1993 and 1999 47 patients underwent PET before (PET(1)) and after (P
It has been generally accepted that increasing aerosols suppress precipitation. The aerosol-induced precipitation suppression was suggested by the study of shallow stratiform clouds. Recent studies of convective clouds showed increasing aerosols could increase precipitation. Those studies showed that intense feedbacks between aerosols and cloud dynamics led to increased precipitation in some cases
The aim of the present study was to explore whether it was possible to differentiate the clinical course and the otomicroscopic appearance of acute otitis media (AOM) caused by common otitis pathogens in an animal model. Systemic interleukin (IL)-6 levels as early markers for bacterial AOM were also studied. Four groups of rats were inoculated with either Streptococcus pneumoniae, Streptococcus py
The Toll-like receptors (TLRs) and the myeloid differentiation factor 88 (MyD88) are key players in the activation of the innate immune defence during microbial infections. Using different murine infection models, we show that MyD88-dependent signalling is crucial for the activation of the innate immune defence against Streptococcus pneumoniae. Our data demonstrate that both local and systemic inf
BACKGROUND: Allergic rhinitis is an inflammatory disease of the upper airway mucosa that also affects leukocytes in bone marrow and peripheral blood. Toll-like receptor 9 (TLR9) is a receptor for unmethylated CpG dinucleotides found in bacterial and viral DNA. The present study was designed to examine the expression of TLR9 in the nasal mucosa and in leukocytes derived from different cellular comp
Over the last few decades, the African Sahel has become thefocus of many studies regarding vegetation dynamics and theirrelationships with climate and people. This is because rainfalllimits the production of biomass in the region, a resource onwhich people are directly dependent for their livelihoods. In thisstudy, we utilized a remote-sensing approach to answering thefollowing two questions: (1)
During the Cold War, along with the Americanization of its popular culture, Finland was also heavily exposed to Soviet ideological influences, including in relation to notions of desirable femininity. From the late 1960s onwards, Soviet influences can be seen in Finnish public discourses on fashion and decorative femininity. Soviet ideals are also reflected in the emphasis on gender neutrality and
We have reconstructed the distribution of extraterrestrial chrome spinels in a marine limestone section across the Frasnian–Famennian stratotype section at Coumiac in southern France, providing the first insights on the types of micrometeorites and meteorites that fell on Earth at this time. The data can test whether the small cluster of roughly coeval, large impact structures is related to an ast
BackgroundMany countries and regions undergo structural changes that intent to improve the effectiveness and quality of care. Until 2007, the municipalities, counties, hospitals and pharmacies shared the smoking cessation activities almost equally in Denmark. Among others, the Danish Healthcare Reform 2007 intended to add responsibility for smoking cessation intervention at county level to the mu
Capsule: Foraging behaviour in the Razorbill Alca torda during breeding was similar to that found elsewhere, aside from dive shape. Aims: To investigate the foraging behaviour of Razorbills during the breeding season at the largest colony in the central Baltic Sea. Methods: A combination of global positioning system (GPS) and time-depth recorder (TDR) devices were used on Razorbills breeding on th
Two imaging techniques are used to investigate the interaction between developed combustion from earlier injections and partially oxidized fuel (POF) ofa subsequent injection. The latter is visualized by using planar laser induced fluorescence (PLIF) of formaldehyde and poly-cyclic aromatic hydrocarbons. High speed imaging captures the natural luminescence (NL) of the prevailing combustion. Three
This paper investigates the outcome of the efforts to economically catch up during theso-called development era in French-speaking West Africa. An attempt is made tomeasure and discuss key elements of social capability over the period 1930–1980 inCôte d’Ivoire and Senegal following Moses Abramovitz’interpretation of socialcapability. The paper distinguishes between four elements of social capabili
One of the greatest challenges for the world today is the reduction of greenhouse gas emissions. As buildings contribute to almost a quarter of the greenhouse gas emissions worldwide, reducing the energy use of the existing building stock is an important measure for climate change mitigation. In order to increase the renovation pace, there is a need for a comprehensive technicaldocumentation that
