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Digitizing the palate : exploring opportunities for digital transformation in the food industry

The modern food industry faces the challenge of catering to diverse consumer preferences while maintaining efficiency and profitability. Rapid shifts in consumer trends, emerging technologies, and evolving regulations make it difficult for companies to keep pace, often resulting in inefficiencies and lost opportunities. The vast amount of data generated across production, supply chains, and market

Nanofibrous Peptide Hydrogels Leveraging Histidine to Modulate pH-Responsive Supramolecular Assembly and Antibody Release

In this work, we investigate the pH-responsive behavior of multidomain peptide (MDP) hydrogels containing histidine. Small-angle X-ray scattering confirmed that MDP nanofibers sequester nonpolar residues into a hydrophobic core surrounded by a shell of hydrophilic residues. MDPs with histidine on the hydrophilic face formed nanofibers at all pH values tested, but the morphology of the fibers was i

Shear force capacity of cross laminated timber beams : Numerical investigations of fracture behaviour

This paper deals with numerical investigations of cross laminated timber (CLT) beams. Previous investigations have revealed discrepancies between experimental test results and suggested design methods regarding shear force capacity of such beams. To gain further understanding of the failure behaviour and the shear force capacity, nonlinear finite element analyses have been performed, using a cohes

Cystatin C-derived measures of renal function as risk factors for mortality and renal replacement therapy in the critically ill – An analysis of the SWECRIT cohort

Purpose: Assess if cystatin C-derived measures of kidney function are associated with mortality in septic- and non-septic intensive care unit (ICU) patients. Methods: Data from adult patients staying >24 h in four ICUs in Sweden from November 2015–December 2018 included. Outcomes were mortality and need for renal replacement therapy (RRT) due to acute kidney injury. Associations between cystatin C

Molecular 3D Characterisation of Drug Distribution and Mg-Stearate Coating on Lactose Carrier Particles by ToF-SIMS and XPS

A common type of inhalation medicine uses a dry powder formulation where the active pharmaceutical ingredient (API) is attached on the surface of carrier particles, often in combination with additional components. The spatial distribution of the API on the carrier particle is critical for the release into the lungs and thus for the efficacy of the drug. In this work, we use ToF-SIMS imaging in com

Broadening the Meanings of Youth Climate Activism : A Review of the Literature from Asia

It is by now a common trope that youth climate activism has become a ‘global phenomenon’. Yet, it also has significant regional variations. This literature review analyses eighteen academic articles on the topic of youth climate activism in Asia. We found that the literature from Asia overall had ambitions to contextualise and nuance international scholarship on youth climate activism. This was ac

A non-genotoxic stem cell therapy boosts lymphopoiesis and averts age-related blood diseases in mice

Hematopoietic stem cell (HSC) transplantation offers a cure for a variety of blood disorders, predominantly affecting the elderly; however, its application, especially in this demographic, is limited by treatment toxicity. In response, we employ a murine transplantation model based on low-intensity conditioning protocols using antibody-mediated HSC depletion. While aging presents a significant bar

Influence of friction material composition on airborne wear particle emissions from dry clutches

Airborne wear particle emissions from dry clutches have been investigated in terms of particle mass and number concentration, size distribution, and chemical composition of a single clutch material. This paper presents a detailed continuation of the investigation. Clutch plates of two different friction materials, i.e., from different manufacturers but for the same automobile applications, are tes

Attohallen – a new attosecond science facility in Sweden

We present the concept of our new high power laser facility Attohallen in Gothenburg, with focus on its first high-order harmonic generation beam line. The key specifications of this facility, including the architecture and operation of the femtosecond drive laser system, the XUV generation part of its first beam line for photon-demanding attosecond timing experiments in the energy range up to abo

Aerosolized Dornase Alfa (DNase I) for the Treatment of Severe Respiratory Failure in COVID-19 : A Randomized Controlled Trial

Background: Lung injury in COVID-19 is characterized by neutrophil invasion and the release of neutrophil extracellular traps (NETs). An aberrant NET formation may induce local inflammation and increase sputum viscosity. Inhalation of DNase I (dornase alfa) is a treatment option that degrades NETs in the airways. Previous case series have indicated positive clinical effects of inhaled dornase alfa

Uppdragsunderskridanden och feltolkning av processhandlingar

17 kap. 3 § rättegångsbalken (RB) omgärdas av omfattande begrepps- och teoribildning. Som exempel har det skrivit tre svenska avhandlingar som har bestämmelsen som huvudtema. När det kommer skiljeförfaranden enligt lagen (1999:116) om skiljeförfarande (LSF) är det en omdebatterad fråga i vad mån tvistemålsprocessens begrepps- och teoribildning bör tillämpas analogt. LSF har ingen uttrycklig bestäm

Prognostic Differences of Adjuvant Radiotherapy in Breast Cancer Cohorts Based on PRLR Genotypes, Expression, and Transcriptional Network Regulation

Background: Prolactin receptor (PRLR) signaling affects breastfeeding and potentially breast cancer treatment response. Methods: The prognostic impact of 20 PRLR single nucleotide polymorphisms (SNPs) in relation to adjuvant treatment groups in patients with primary breast cancer (n = 1701, 2002–2016, Sweden) was evaluated. Genomic DNA was genotyped on Illumina OncoArray, and survival analyses wit

Hard X-ray stereographic microscopy for single-shot differential phase imaging

The characterisation of fast phenomena at the microscopic scale is required for the understanding of catastrophic responses of materials to loads and shocks, the processing of materials by optical or mechanical means, the processes involved in many key technologies such as additive manufacturing and microfluidics, and the mixing of fuels in combustion. Such processes are usually stochastic in natu

Support Needs Among Older Tenants Living in Public Housing in Sweden : Perspectives of Janitors and Maintenance Staff

Neighborhood support can improve aging in place for older adults, but research on the role of public housing staff in supporting older tenants is lacking. Twenty-nine participants (janitors, n = 11; maintenance staff, n = 18) collected data about critical situations among older tenants residing in apartments in Sweden. Modifying the Critical Incident Technique (CIT) and applying a mixed-methods de

Mitochondrial heteroplasmic shifts reveal a positive selection of breast cancer

BACKGROUND: Breast cancer is, despite screening, not always detected early enough and is together with other tumor types known to shed genetic information in circulation. Unlike single-copy nuclear DNA, mitochondrial DNA (mtDNA) copies range from 100s to 10,000s per cell, thus providing a potentially alternative to identify potential missing cancer information in circulation at an early stage.METH