Filtyp
Aims and objectives: To explore healthcare professionals' conceptions of caring for sick children in home care services. Background: Families often prefer home care to hospital care, and the number of home care services for children is increasing. Caring for children at home has been recognised as challenging for healthcare professionals in home care services used to providing care predominately f
The effects of socio-economic/occupational factors on gastric cancer at various subsites (including corpus, cardia and unspecified cancers) are not well known. To investigate this issue, we carried out a follow-up study on the economically active Swedish population, based on the Swedish Family-Cancer Database. We calculated standardized incidence ratios and 95% confidence intervals for different o
Objective: The objective of this study was to examine the associations between socioeconomic/occupational factors and pancreatic cancer. Methods: The Swedish Family-Cancer Database was used to calculate standardized incidence ratios for different social classes and occupational groups. Lung cancer risks were also determined. The reference group was all the economically active population. Results:
The reasons for the high risk of contralateral breast cancer are not understood, although polygenic mechanisms have been suggested to be involved. The nationwide Swedish Family-Cancer Database was used to examine the interaction of the risks for contralateral and familial cancer. Relative risks were separately determined for contralateral and familial breast cancers, and these were tested for addi
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a progressive disabling condition, for which tobacco smoking, environmental pollution, inherited alpha-antitrypsin deficiency and their interactions are predisposing factors. We carried out a family study on COPD in order to address the role of heritable and environmental risk factors at a population level.METHODS: In a nationwide study o
BACKGROUND: Asthma is a common disabling condition, with known environmental and familial risk factors and with their assumed interactions. We wanted to carry out a family study on asthma to address gene-environment interactions at a population level.METHODS: We conducted a nation-wide study on familial risks for asthma. An asthma database was constructed by linking the Multigeneration Register on
OBJECTIVES: The aim of this study is to investigate associations between hospitalization for epilepsy and two factors: socioeconomic status and occupation.DESIGN AND SETTING: A nationwide database was constructed in Sweden by linking the Swedish Census to the Hospital Discharge Register to obtain data on all first-time hospitalizations for epilepsy in adults in Sweden during the study period (1987
Migraine and other headaches are common disabling conditions, reducing the quality of life in the affected individuals. The unambiguous definition of familial risk for subtypes of migraine and other headaches will advance the search for the heritable causes of these conditions and their underlying mechanisms. We aim at defining familial risks for siblings to be hospitalized because of migraine or
Background: Animal models of human diseases are often used in biomedical research in place of human subjects. However, results obtained by animal models may fail to hold true for humans. One way of addressing this problem is to make animal models more similar to humans by placing human tissue into animal models, rendering them chimeric. Since technical and ethical limitations make neurological dis
In this work a simplified approach to array optimization for the DC resistivity and induced polarization method have been created and tested. The optimization method uses the centre of the sensitivity function for the individual electrode configurations, called the mass centre, which is spread over the area of investigation, wherefrom the name Spread of Mass Centre (SMC). This array has been teste
BACKGROUND: Traumatic acute subdural hematomas (ASDHs) are associated with high rate of morbidity and mortality, especially in elderly individuals. However, recent reports indicate that the morbidity and mortality rates might have improved.OBJECTIVE: To evaluate postoperative (30-d) mortality in younger vs elderly (≥70 yr) patients with ASDH. Comparing younger and elderly patients, the secondary o
With data from two comparable corpora of spoken British English, the London-Lund Corpus and the new London-Lund Corpus 2, this study tracks the development of the reactive what-x construction half a century back in time. The study has two goals: (i) to describe the uses of the construction over time and (ii) to establish the motivations and mechanisms related to its development in spoken dialogue.
The phage Mu DNA transposition system provides a versatile species non-specific tool for molecular biology, genetic engineering and genome modification applications. Mu transposition is catalyzed by MuA transposase, with DNA cleavage and integration reactions ultimately attaching the transposon DNA to target DNA. To improve the activity of the Mu DNA transposition machinery, we mutagenized MuA pro
Background Our overall goal is to improve clinical care for inpatients with chronic heart failure (CHF). A retrospective assessment of CHF patients admitted to our hospital over the past decade (2005 vs. 2014) indicated a need for better strategies to evaluate clinical treatment, implement best practices and achieve optimal patient outcome. To that purpose, we developed a standardized plan to impr
The phase diagram of the Al–B–C system has been calculated at pressure 7.7 GPa using models of the phenomenological thermodynamics with the interaction parameters derived from the experimental data on the phase equilibria at high pressures and temperatures.
BACKGROUND: The optimal advanced heart failure (HF) therapy strategy for patients aged 60 or older with end-stage HF refractory to optimal medical therapy remains uncertain. This study compares outcomes of three advanced HF therapy strategies in this patient population. METHODS: A single-center retrospective study was conducted in 95 patients aged 60-73 years who had undergone isolated heart trans
The General Data Protection Regulation (GDPR) came into force in May 2018. The aspiration of providing for a high level of protection to individuals’ personal data risked placing considerable constraints on scientific research, which was contrary to various research traditions across the EU. Therefore, along with the set of carefully outlined data subjects’ rights, the GDPR provides for a two-leve
This study investigated the relationship between perceived indoor temperature in winter and frailty among community-dwelling older people. This cross-sectional study included 342 people 65 years and older in Japan. Participants answered questions about demographics, frailty, housing, and perceived indoor temperature in winter. Participants were grouped based on perceived indoor temperature (Cold o
While deforestation and forest degradation have gained attention in recent years not least at the UN climate negotiations, a third “de”, i.e., defaunation, has to a great extent been overlooked. Human-induced faunal loss does not only reduce tree species diversity, but also significantly erodes key ecosystem services and functions and further disadvantages local communities. In this article, we an
