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Aims: To study the cumulative incidence of hospitalization for severe diabetic vascular complications in childhood onset type 1 diabetes patients with special regards to age at onset and gender. Methods: The Swedish Childhood Diabetes Register (SCDR) was linked to the Swedish Hospital Discharge Register up to 31 December 2004. The following diagnoses were traced: diabetic kidney disease, myocardia

The discussion about weather one should pay expensive management fees to let professionals manage your money or if one should simply invest in an almost costless index fund has been going on for decades. This study’s objective is to investigate if the most popular actively managed mutual funds in Sweden can outperform the most popular Swedish passive broad market index fund. The study analyzes 62

Having notoriously escaped the operation table to be cut open for a full intestine check-up, the anatomy of the acclaimed ‘troops for influence’- assumption finally faces a full body search. Although appearing to be somewhat of a tacitly accepted ‘truth’ both in the academic and political world, there is confusion as to how we might actually understand the assumption of ‘troops for influence’ and

We present a sample of 705 local giant stars observed using the New Mexico State University 1 m telescope with the Sloan Digital Sky Survey-III/Apache Point Observatory Galactic Evolution Experiment (APOGEE) spectrograph, for which we estimate stellar ages and the local star formation history (SFH). The high-resolution (R ̃ 22,500), near infrared (1.51-1.7 μm) APOGEE spectra provide measurements o

BackgroundElbow strength ratios in relation to performance level, in male and female climbers, are scarcely documented. The aim of this study was to investigate elbow muscle strength, strength ratio and hand grip strength in climbers and its potential relationship to performance level.HypothesisWe hypothesized that there is a relationship between performance level and various strength variables an

This study describes the outcome of patients receiving haematopoietic stem cell transplantation (HSCT) to treat severe refractory autoimmune cytopenia. The registry of the European Group of Blood and Marrow Transplantation holds data on 36 patients receiving 38 transplants, the first transplant was autologous for 27 and allogeneic for nine patients. Patients had autoimmune haemolytic anaemia (auto

The purpose of this study was to identify new prognostic biomarkers with clinical impact in malignant peripheral nerve sheath tumor (MPNST), a highly aggressive malignancy for which no consensus therapy exists besides surgery. We have used tissue microarrays (TMAs) to assess in situ expression of 14 cell-cycle-regulating proteins in 64 well-characterized MPNST patients: 36 sporadic and 28 with neu

A dinuclear manganese complex ([Mn2L(m-OAc)2]PF6) has been synthesized, where L is the trianion of 2,6-bis{[(2-hydroxy-3,5-di-tert-butylbenzyl)(2-pyridylmethyl)amino]methyl}-4-methylphenol, a ligand with three phenolate groups. The two pseudo-octahedrally coordinated Mn ions are bridged via the two bidentate acetate ligands and the 4-methylphenolate group of the ligand. We have characterized the c

Core excitation from terminal oxygen O-T in O-3 is shown to be an excitation from a localized core orbital to a localized valence orbital. The valence orbital is localized to one of the two equivalent chemical bonds. We experimentally demonstrate this with the Auger-Doppler effect which is observable when O-3 is core excited to the highly dissociative O(T)1S(-)17a(1)(1) state. Auger electrons emit

Aims: The REPRISE IIE trial aimed to evaluate outcomes following transcatheter aortic valve implantation of the fully repositionable and retrievable LOTUS valve with a unique seal designed to minimise paravalvular leak (PVL). Methods and results: This prospective, multicentre study enrolled 250 patients with severe aortic stenosis considered high-risk for surgery by a multidisciplinary Heart Team.

BACKGROUND Madagascar is the fourth biggest island and one of the poorest countries in the world, with more than 75 % of the 24 million inhabitants living under poverty line. The health care system in the country is under development, as well as the field of rehabilitation services and the area of prosthetic and orthotic services in specific. There is very limited published research concerning reh

About 3-6% of vasectomized men requested vasectomy reversal, for various reasons. Vasal patency (VP) is an important surrogate outcome of vasectomy reversal. This article reviews the impact of surgical skills, surgical approaches, intraoperative vasal fluid characteristics and the length of obstructive interval on VP. Based on the best available evidence, the rate of patency is related to the oper

An improved technique for direct vision chorionic biopsy that gives a clear view of the amniotic sac was developed. With this technique, used in 48 women prior to vacuum aspiration and in six cases for diagnosis (karyotyping or enzyme analysis), it was possible to obtain chorionic villi free from contamination by maternal tissue. It was also possible to pick out villi (rich in blood vessels and wi

Bark lesions on beech are mostly caused by frost damage and/or insect and fungal infections. Liming, treatment with wood ash and N-fertilization were hypothesised to affect this type of damage. The frost sensitivity was measured as an index of injury, calculated from electrolytic leakage of bark samples. Samples were taken from the same trees in August and November at five sites. Two sites had bee

After a long period of stagnation, Syria during the nineteenth century arose to a cultural and social renaissance. One important field of development was education. An article published in Beirut in 1883 sheds important light on this. External impulses were important, but much of the development effort was indigenous. There were significant differences in the level of education between towns and t

Popular Abstract in Swedish Inledning I detta avhandlingsarbete studeras Mycoplasma pneumoniae (MP) och influensa virus ur olika perspektiv. Dessa två smittämnen orsakar båda årliga utbrott med luftvägsinfektioner som ibland blir omfattande epidemier. I båda fallen kan symptomen variera från lätta förkylningsbesvär till mycket svåra, ibland livshotande lunginflammationer. Infektion med MycoplasmaDiagnostic tests based on nucleic acid amplification have become available for Mycoplasma pneumoniae (MP) and influenza viruses. Here, an MP PCR test detected 100% of infections during the first three symptomatic weeks, whereas classical serology detected 21% week 1, 56% week 2, and 100% week 3. Positive PCR results were uncommon in healthy individuals. Levels of MP DNA were significantly higher i

The effects of hypothermia on hypoglycemic brain damage were studied in rats after a 30-min period of hypoglycemic coma, defined as cessation of spontaneous EEG activity. The rats were either normothermic (37 degrees C) or moderately hypothermic (33 degrees C). Morphological brain damage was evaluated after various periods of recovery. Hypothermic animals with halothane anesthesia never resumed sp

Popular Abstract in Swedish Anorexia nervosa är en sjukdom som i över 100 år förbryllat den medicinska vetenskapen. Det är en sjukdom med okänd orsak, oförutsägbart förlopp och där ingen enskild behandlingsmetod kunnat hävda sig som den mest effektiva. Den självförvållade svält, som är det främsta symtomet i sjukdomen, har i alla tider fascinerat mänskligheten. Trots att det är en relativt sällsynThis dissertation presents a study of 26 adolescent anorexia nervosa patients and their families regarding family function and treatment. Family function was studied at the start of treatment and at two-year follow-up. In a Nordic study, 49 families were studied at the start of treatment, and different sub-groups of families were examined. The 26 patients took part in a randomised controlled study