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The aim of this study was to understand the reasons why Spain has one of the lowest prevalence rates of intimate partner violence against women (IPVAW) in the European Union. Using a qualitative and inductive research approach, a total of five focus groups (n = 19) and 10 unstructured interviews with key informants were conducted. Three main categories were identified as possible explanations of t
From an evolutionary point of view a pathogen might benefit from regulating the inflammatory response, both in order to facilitate establishment of colonization and to avoid life-threatening host manifestations, such as septic shock. In agreement with this notion Streptococcus pyogenes exploits type I IFN-signaling to limit detrimental inflammation in infected mice, but the host-pathogen interacti
Abstract in Uncoded languages Tarptautiniai klimato kaitos susitarimai ir Europos Sąjungos teisės aktai veikia skirtingus valdymo lygmenis, įskaitant nacionalines teisės sistemas ir administravimo modelius. Disertacijoje iškeltas tyrimo klausimas – Kaip Lietuva, konkrečiai pramonės sektorius, įgyvendina šiltnamio efektą sukeliančių dujų (toliau – ŠESD) emisijų mažinimo reikalavimus, nustatytus KioInternational climate change agreements and the European Union legislation have an influence on different levels of governance, including national legal systems and administrative schemes. The following research question is addressed in the doctoral dissertation: “How does Lithuania, specifically the industrial sector, implement GHG reduction requirements under the Kyoto Protocol and the European
The immune system is an important part of the physiology of higher organisms. In the immune system antibodies play a key role in neutralizing and clearing potentially lethal threats from the environment. The importance of antibodies in the immune system has made them come to the attention as a tool in chemistry and medicine. This thesis, which is based on four original papers, deal with antibody d
This paper presents the development as well as the architecture of a computer-aided dedicated fixture design system intended to support the design of lightweight (carbon fiber composite) grippers for a major truck company. Lightweight grippers were required due to the increasing production rates in the automotive industry. The current robotic equipment was facing diverse problems during transporta
AIMS: To compare the clinical characteristics of Type 2 diabetes (T2DM) between immigrants from the Middle-East and Swedish patients. METHODS: The study group included 450 consecutive patients with T2DM, 379 Swedish-born aged 61 +/- 12 years and 71 patients originally from the Middle-East aged 50 +/- 11 years from the diabetes clinic of Malmo University Hospital. RESULTS: Onset of diabetes had occ
Att E-handeln ökat stort de senaste åren har inte gått ouppmärksammat och dess inslag har märkts både privat och inom näringslivet. Den fysiska handeln har ändrats handel via internet vilket är en utveckling från byteshandel som var en av de tidigaste handelsformerna. Sedan internet, och E-handelns, lansering i början av 1990-talet har utvecklingen gått snabbt och de senaste tjugo åren har omsättnThe fact that e-commerce has increased significantly in recent years has not gone unnoticed, and its features have been marked in both private life as well as in business. The physical commerce has changed to an increased shopping through the internet, which is a development of the trade of goods that was one of the earliest commercial forms. Since the internet, and thereby the E-commerce, was lau
Popular Abstract in Swedish Immunsystemet skyddar kroppen mot infektion. För att kunna skydda mot infektion krävs att immunsystemet är utrustat med kraftfulla biokemiska motmedel. Ett sådant motmedel är antikroppar. Antikroppar är proteiner som känner igen och specifikt binder till andra molekyler via en s k molekylbindande klyfta. När antikropparna har bundit in till en molekyl på t ex en bakteriPrimary infections and vaccination stimulates the immunesystem to produce memory cells that rapidly respond to reexposure of the same antigen. These memory responses are dependent on an adaptive type of immunity that sustains the reactivity of the immune system by long-lived memory immune cells. From an evolutionary perspective adaptive immunity as such appears to be restricted to jawed vertebrate
Health is a universal right, nevertheless, not all people have the same opportunities to fully enjoy it without facing financial difficulties. Universal Health Coverage has the potential to break the health-poverty trap, supporting people with the opportunity of building a healthy structure, essential for a sustainable human and economic development. This paper explores how individual characterist
The Cd247 gene encodes for a transmembrane protein important for the expression and assembly of TCR/CD3 complex on the surface of T lymphocytes. Down-regulation of CD247 has functional consequences in systemic autoimmunity and has been shown to be associated with Type 1 Diabetes in NOD mouse. In this study, we have utilized the wealth of high-throughput sequencing data produced during the Encyclop
The effect of prostate-specific antigen (PSA) screening on prostate cancer mortality remains debated, despite evidence from randomized trials. We investigated the association between prostate cancer incidence, reflecting uptake of PSA testing, and prostate cancer mortality.
We report that many histone modifications are unevenly distributed over the HPV16 genome in cervical cancer cells as well as in HPV16-immortalized keratinocytes. For example, H3K36me3 and H3K9Ac that are common in highly expressed cellular genes and over exons, were more common in the early than in the late region of the HPV16 genome. In contrast, H3K9me3, H4K20me3, H2BK5me1 and H4K16Ac were more
The performance of new firms is important for economic development but research has produced limited knowledge about the key relationships among growth, profitability, and survival for new firms. Based on evolutionary theory, we develop a model about how new firms resolve uncertainty about their ability to prosper in a market by monitoring changes in profitability. Our model predicts selection pre
Disease and death caused by bacterial infections are global health problems. Effective bacterial strategies are required to promote survival and proliferation within a human host, and it is important to explore how this adaption occurs. However, the detection and quantification of bacterial virulence factors in complex biological samples are technically demanding challenges. These can be addressed
Global leaders agree on the need to substantially decarbonize the global economy by 2050. This paper compares potential costs associated with different policy pathways to achieve tourism sector emission reduction ambitions (−50% by 2035) and transform the sector to be part of the mid-century decarbonized economy (−70% by 2050). Investment in emissions abatement within the tourism sector, combined
There has been much debate on the topic of whether stricter environmental regulations can promote environmental performance and economic performance at the same time. Different researchers have used different indicators to measure environmental performance and economic performance in their empirical studies. However, it is a surprise that few studies have checked the relationship between environme
Background: The rate of biological ageing is individual and represents the steady decrease in physiological and mental functions. Adverse social factors have been shown to influence this process. Self-perceived early ageing (SEA) might be a useful indicator of early biological ageing and increased mortality risk. The aim of this population-based study was to identify markers of SEA, including telo
Most viruses in human skin are known to be human papillomaviruses (HPVs). Previous sequencing of skin samples has identified 273 different cutaneous HPV types, including 47 previously unknown types. In the present study, we wished to extend prior studies using deeper sequencing. This deeper sequencing without prior PCR of a pool of 142 whole genome amplified skin lesions identified 23 known HPV ty
Screening mammography plays a key role in the early detection of breast cancer, however, estimates of sensitivities (48-88%) and specificities (82-98%) suggest that the diagnostic accuracy can be improved (1, 2, 3). Breast tomosynthesis (BT) is a 3D technique that is expected to improve breast cancer detection compared to screen-film and digital mammography DM). This work presents two clinical obs
The 2008–2009 global financial crisis triggered ‘Green Energy Economy’ (GEE) policy packages to stimulate green growth in many countries. China soon became a leader and, supported by its 11th Five-Year Plan (2006–2010), devoted approximately one-third of its US$ 647 billion stimulus package to green energy technologies. Since then, numerous policy instruments have been implemented to encourage ‘Gr
