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Popular Abstract in Swedish Våra celler är täckta av kolhydrater (socker) som är kopplade till proteiner och lipider på cellens yta. Olika celler presenterar olika socker, och en och samma cell kan dessutom ändra sitt sockeruttryck beroende på hur den mår och vad den vill utföra, till exempel dela sig eller dö, en effekt man ofta ser i cancer. På så sätt fungerar sockerstrukturerna som en kod som There is an intensive interest in characterising the structure and function of galectins, which is not surprising given their many important cellular functions and strong implications in human disease. Understanding the mechanisms involved in galectin functions will help to find selective and novel strategies for disease treatment and diagnosis. A key to this lies in their carbohydrate binding spe

HAMLET, a complex of α-lactalbumin and oleic acid, preferentially kills cancer cells and is also effective in vivo. HAMLET causes apoptosis but cells die even if this pathway is inhibited. Thus, the role of autophagy, an alternative cell death pathway, was examined. During autophagy double membrane-enclosed autophagosomes form around cellular material and deliver it to the lysosomes for degradatio

Antibody-based microarrays is a novel technology with great promise for high-throughput proteomics. The process of designing high-performing arrays has, however, turned out to be challenging. Here, we have designed the next generation of a human recombinant scFv antibody microarray platform for protein expression profiling of nonfractionated biotinylated human plasma and serum proteomes. The setup

Background Combined oral contraceptives are classified by the International Agency for Research on Cancer as a cause of cervical cancer. As the incidence of cervical cancer increases with age, the public-health implications of this association depend largely on the persistence of effects long after use of oral contraceptives has ceased. Information from 24 studies worldwide is pooled here to inves

Hur kan det komma sig att en relativt stor andel lärare på en och samma gång är missnöjda med en rad arbetsvillkor och upplever att arbetet är meningsfullt? Varför är, med andra ord, många lärare nöjda med sin yrkesutövning som lärare samtidigt som de är missnöjda som anställda? Frågeställningarna har attackerats från flera håll med utgångspunkt från läraryrkets och skolans utveckling under de sen

Referat gällande en studie som diskuterar socioekonomiska faktorer relaterat till kriminalitet.A summary of a study showing that socioeconomic status may not be so strongly correlated to crime as previously believed.

The study of a time-frequency image is often the method of choice to address key issues in cognitive electrophysiology. The quality of the time-frequency representation is crucial for the extraction of robust and relevant features, thus leading to the demand for highly performing spectral estimators. We consider a stochastic model, known as Locally Stationary Processes, based on the modulation in

The impacts of natural disasters on communities living in hazard prone areas are wide ranging and complex. In Mwanza, steep slopes, rocky hills and river valleys are inhabited by society's poorest people. These areas are prone to natural disasters. Residents have accumulated coping mechanisms for disaster risks and impact reduction. We combine spatial data, household surveys and data from focus gr

Blastocystis is an enteric protozoan purportedly associated with numerous clinical cases of diarrhea, flatulence, vomiting, and other gastrointestinal symptoms. Despite new knowledge of Blastocystis cell biology, genetic diversity, and epidemiology, its pathogenic potential remains controversial. Numerous clinical and epidemiological studies either implicate or exonerate the parasite as a cause of

Neuroblastoma is a neural crest-derived childhood tumor of the peripheral nervous system in which MycN amplification is a hallmark of poor prognosis. Here we show that MycN is expressed together with phosphorylation-stabilizing factor CIP2A in regions of the neural plate destined to form the CNS, but MycN is excluded from the neighboring neural crest stem cell domain. Interestingly, ectopic expres

Inom ett par år kommer det nya materialforskningscentret ESS, The European Spallation Source, att stå färdigbyggt. Det kommer då vara det mest avancerade forskningsinstitutet i sitt slag och leverera upp till 30 gånger fler neutroner än någon annan neutronkälla i världen. En av de viktigaste komponenterna på ESS är det s.k. strålmålet som består av nästan 7000 bitar av det metalliska grundämnet voThe European Spallation Source (ESS), which is currently under construction in Lund, will use pure tungsten as the spallation neutron target. The tungsten will be irradiated by a 2 GeV proton beam, pulsed at a repetition rate of 14 Hz. Each pulse will deposit 357 kJ in the tungsten causing an instantaneous temperature rise of approximately 100 °C, during the 2.86 ms pulse duration. The target is w

Background: For different migrant groups living in an area with few people from the same ethnic background is associated with increased psychosis incidence (the ethnic density effect). We set out to answer the question: are there generational differences in this effect? Methods: Analysis of a population based cohort (2.2 million) comprising all those born 1st January 1965, or later, living in Denm

The article presents an analysis of boundary work within the context of care for the elderly, where violence appears to be widespread though still relatively unacknowledged. By resorting to certain descriptive – often jocular – modes, the staff designate aggressive acts committed by patients as 'non-violent'. This occurs although intent, responsibility, and injury – all common criteria associated

Liberalismen är under förändring. Traditionellt var liberalismen en politisk position som hävdade den enskildes rätt mot staten eller majoriteten. Friheten att uttrycka sina politiska åsikter, organisera sig politiskt eller utöva sin religion sågs som demokratins kärna. Liberalismen värnade ofta gränsen mellan det privata och det offentliga samt individens rättigheter gentemot staten och kollektiv

A description and analysis of organizations and institutions responsible for land use planning and transport planning in a fast growing African metropolitan area, Dar-es-Salaam.

Immunization strategies against commensal bacterial pathogens have long focused on eradicating asymptomatic carriage as well as disease, resulting in changes in the colonizing microflora with unknown future consequences. Additionally, current vaccines are not easily adaptable to sequence diversity and immune evasion. Here, we present a "smart" vaccine that leverages our current understanding of di

The aim of this thesis has been to investigate women's experience of the Methadone maintenance treatment and what help they believe they need to be able to recover and to improve their social life and whether the medical- and social workers share the similar view. Our method of investigation has been qualitative interviews with four women in the program, two nurses and a counsellor at the met

This article examines the production of climate-related loss, specifically loss of access to land, among Indigenous and ethnic minority farming communities in northeastern Cambodia. We analyse how rapid socio-environmental and political-economic changes are eroding smallholder farmers' capacities to cope with climate impacts and can lead to what we call climate-related loss. We show how climate ch

Summary of RWI activities during the first week of COP27  - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outre

https://rwi.lu.se/news/summary-of-rwi-activities-during-the-first-week-of-cop27/ - 2026-07-12