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BACKGROUND: Inflammation and immune responses are considered to be very important in the pathogenesis of atherosclerosis. Lipid accumulation in macrophages of the arterial intima is a characteristic feature of atherosclerosis which can influence the inflammatory potential of macrophages. We studied the effects of lipid loading on the regulation of TNF expression in human monocyte-derived macrophag
The colorimetric 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay was standardized for direct detection of rifampin-resistant Mycobacterium tuberculosis in sputum samples. The sensitivity and specificity of the direct MTT assay matched those of the standard indirect susceptibility assay on 7H10 medium, and interpretable results were obtained for 98.5% of the samples within
Popular Abstract in Swedish Studiet av entreprenøren er ikke et studium om en «helt på sin hvite hest», som er en ikke uvanlig kritikk av vellykkete næringsdrivende, men snarere en analyse av helt vanlige menneskers tanker, drømmer og liv. Entreprenørene er vanskelige å finne for de er sjeldent forekommende i befolkningen. De er viktige fordi de utfører innovasjoner, som innebærer at man blir i stThis dissertation, which is an analysis of the entrepreneur at the micro level, supplements and underpins the understanding and use of the entrepreneur as an agent of social change in the analysis of economic change at the macro level. The aim of the thesis is firstly to seek out and identify businessmen of our time who claim to be innovative, and secondly to un-dertake a qualitative study and ana
The remaining carbon stocks in wet tropical forests are currently at risk because of anthropogenic deforestation, but also because of the possibility of release driven by climate change. To identify the relative roles of CO2 increase, changing temperature and rainfall, and deforestation in the future, and the magnitude of their impact on atmospheric CO2 concentrations, we have applied a dynamic gl
Spatial and temporal changes in South African solar UV-B (280-315 nm) exposure were modeled and mapped at 2.5 km2 resolution using ozone, relative humidity, cloud amount and elevation data. Computations indicated large natural gradients in UV-B exposure ranging from a 34.2% change over 14o of latitude to a 44.2% change over 16o of longitude. Modelling of future scenarios in annual UV-B exposure in
Campylobacteriosis is a zoonotic disease in which birds have been suggested to play an important role as a reservoir. We investigated the prevalence of Campylobacter jejuni subsp. jejuni in black-headed gulls (Larus ridibundus) in southern Sweden with the aim of examining the nature of C. jejuni infection in this bird species. Birds were sampled in four sampling series each year during 1999 (n = 4
A new immunoassay for the detection of hepatitis C core antigen (HCVcoreAg) in peripheral blood during serological window-phase was evaluated among healthy blood donors, commercially available hepatitis C virus (HCV) seroconversion panels and in-house specimens from individuals undergoing seroconversion. Among 1964 low-risk blood donor samples, seven samples were initially reactive but only one wa
A hepatitis C virus (HCV) genotyping PCR assay based on type-specific primers was expanded to include genotype 6a as well as genotypes 1a, 1b, 2a, and 3a. The nucleotide sequences of a 194-bp fragment in the center of the HCV core gene showed that the homologies between genotype 6a and genotypes 1a, 1b, 2a, 2b, 3a, and 5 were 81.2, 82.1, 73.8, 77.3, 81.4, and 78.9%, respectively. A high degree of
Popular AbstractInnovation, skapandet av nya produkter och processer, är i hög grad ojämnt fördelat över det geografiska rummet. Denna ojämna fördelning har stor betydelse för regionala ekonomiers relativa framgång. Geografiskt koncentrerat kunskapsutbyte mellan företag och andra organisationer är många gånger avgörande för dessa aktörers sammanlagda innovativa kapacitet, och därmed för regionens Innovation, the act and outcome of making something novel, is unevenly distributed across the geographical landscape. This uneven distribution has a profound impact on the differential success of regional economies. Localized learning between co-located firms and organizations provides an important source of increased innovation for regions to face challenges posed by increasingly global competiti
Two different antennas for use in implanted pacemakers are analyzed by simulation and measurement. The analysis was made with an FDTD-code. The simulations and measurements show good agreement. The SAR values for both the antennas are within the limits recommended by ICNIRP when the antenna is fed with 25 uW.
Popular Abstract in Swedish I debatterna om sociala och ekonomiska frågor under 1800-talets första hälft utvecklades grundvalarna för de förhållningssätt till arbetslöshetsfrågan som sedan återkommit i skilda former. Det gällde t.ex. det perspektiv som betonade politikens roll och behovet av statlig intervention för att stimulera produktion och sysselsättning. Det gällde också det renodlade marknaLabour market policy has been at the forefront of economic and political debate in Sweden during the postwar period. Much research effort has been focused on the evolution of labour market policy and its historical roots. The time-perspective has often been narrow, however, and has very seldom extended to include the period prior to the first two decades of the twentieth century. This study emphas
Tourism is currently responsible for the largest, annual human migration in history. This great movement of people has significant positive and negative consequences on nature, societies, cultures and economies. Desired worldwide for its economic benefits, tourism is anticipated to double during the next 20 years, and the multiple consequences of such rapid growth,,call for a preventative approach
This chapter provides the first all-European overview of diverse aspects of living standards in a period when industrialisation and modernity began to show up in substantial improvements in general living conditions. Most obvious is this seen in the increase of life expectancy. A substantial contribution came from the decline in infant mortality which occurred almost simultaneously over large part
This paper considers how researchers can best establish a forward trajectory in their work, individually and collectively. The suggestion is sometimes made in academic circles that it is inappropriate to present work that revisits an area previously discussed within the field. While we accept that any published paper should make an original contribution to what is collectively known about a partic
The EU has set ambitious targets for renewable energy in its ‘energy & climate change package’ and proposal for a Directive on renewables. The latter sets national renewable energy targets for each Member State to reach the overall objective of 20% consumption by 2020. The challenge lies on how these targets can be met, and what kind of role bioenergy has to play in it. The EU Biomass Action P
The evaporative gas turbine pilot plant (EvGT) has been in operation at Lund Institute of Technology in Sweden since 1997. This article presents the latest development in the evaporative technology, the evaporation of bio-ethanol in a gas turbine power plant as a means to reduce the emission of greenhouse gases. Bio-ethanol is produced from a feedstock consisting of corn-stover, and the bio-ethano
