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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 192376 sökträffar

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Tissue factor (TF) expressed at the protein level includes two isoforms: The membrane‑bound full‑length TF (flTF) and the soluble alternatively spliced TF (asTF). flTF is the major thrombogenic form of TF, whereas asTF is more closely associated with tumor growth, angiogenesis, metastasis and cell growth. In order to further investigate the different expression and functions of TF splice variants,

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Comprehensive results on the production of unidentified charged particles, π±, K±, KS0, K∗(892)0, p, p, φ(1020), Λ, Λ, Ξ-, Ξ+, Ω-, and Ω+ hadrons in proton-proton (pp) collisions at s=7 TeV at midrapidity (|y|

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Längs stränderna i Italien, Spanien och vid Öresund har vi alla hittat plastföremål som flyter i havet och ligger på stränderna. I Europa hamnar upp till en halv miljon ton plastavfall i haven varje år. Det motsvarar 66 000 sopbilar som dumpar sitt avfall direkt i havet istället för återvinningscentralen. Efter att frågan vuxit under de senaste åren har EU-länderna nu tagit upp kampen mot detta pr

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BACKGROUND: Fetal/neonatal alloimmune thrombocytopenia (FNAIT) is the platelet counterpart of hemolytic disease of the newborn. Most severe cases of FNAIT are caused by antibodies against human platelet antigen-1a (HPA-1a). HPA-1a–negative women giving birth to an HPA-1a–positive child are at risk of becoming HPA-1a–immunized, particularly women who are HLA-DRB3*01:01–positive. The aim of the stud

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While there is a huge literature on exchange rate systems since the classical gold standard, less research has been devoted to comparisons of the different arguments that guided the choices. While the origin of the international gold standard in the 1870s was a result of silver coins disappearing from circulation due to rising silver prices, the gold standard has later been interpreted as a quest

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Artikel om den assyriska lobbningen vid fredskonferensen i Paris 1919.

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Background Matrix metalloproteinases (MMP´s) are known biomarkers of atherosclerosis. MMP´s are also involved in the pathophysiological processes underlying chronic obstructive pulmonary disease (COPD). Cigarette smoking plays an important role in both disease states and is also known to affect the concentration and activity of MMP´s systemically. Unfortunately, the epidemiological data concerning

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The secondary injury cascades exacerbating the initial brain injury following intracerebral haemorrhage (ICH) are incompletely understood. We used dual microdialysis (MD) catheters placed in the perihaemorrhagic zone (PHZ) and in seemingly normal cortex (SNX) at time of surgical ICH evacuation in ten patients (range 26-70 years). Routine interstitial MD markers (including glucose and the lactate/p

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Understanding the carbon dynamics of the terrestrial biosphere during climate fluctuations is a prerequisite for any reliable modeling of the climate-carbon cycle feedback. We drive a terrestrial vegetation model with observed climate data to show that most of the fluctuations in atmospheric CO2 are consistent with the modeled shift in the balance between carbon uptake by terrestrial plants and ca

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This article explores middle managers in the professions from their position in the sandwiched middle. Based upon interviews with senior academics in management roles and their subordinates in UK business schools, we investigate this experienced middle through a metaphor that informs one particular subject position: to be an umbrella carrier. This position entails protecting subordinates from what

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In her chapter, Karlsson explores the mainstream media reception of three mainly digital Swedish campaigns against sexual violence between 2010-2013: ##prataomdet/talkaboutit, #mörkertalet/the darkfigures, and #fatta/getit. She traces the ways in which the campaign lines of contention and the campaign testimonies are re-framed for new audiences by mainstream media. By mainly investigating headlin

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Sharing Cities Sweden aims to put Sweden on the map as a country that actively and critically works with the sharing economy in cities. The objectives of the program are to develop world-leading test-beds for the sharing economy in Stockholm, Gothenburg, Malmö and Umeå as well as develop a national node to significantly improve national and international cooperation and promote an exchange of expe

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This paper presents and discusses a recently digitized, dataset of strikes and lockouts in Sweden for the period 1859-1902. The dataset, which originally was collected by Axel Raphael by retrospectively browsing through newspapers, pre-dates the Swedish official statistics on work stoppages that began in 1903. Whereas Raphael’s data have been used to illustrate the long-run development of strikes,

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This article takes the notion of crisis as a helpful analytical entry point to unfold the tem- poralities and modalities of the machinery of violence as manifested in men’s abuse of their female partners in Vietnam. Based on ethnographic research I conducted over the years, the article argues that some types of crises might be episodic, and thus a bracketing of daily life, while others, such as in

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This article contributes to the growing literature on the impact of colonial legacies on long-run development. We focus on Kenya, where it is previously argued that land tenure and taxation policies created an impoverished class of wage workers leading to lower living standards, high inequality, and stunted economic development. We take issue with this interpretation. Using archival sources, we ma

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The temperature dependence of the conformational properties in simulations of the intrinsically disordered model protein histatin 5 has been investigated using different combinations of force fields, water models, and atomistic and coarse-grained methods. The results have been compared to experimental data obtained from NMR, SAXS, and CD experiments to assess the accuracy and validity of the simul