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The local governments of EU member countries are attracted to the possibility of receiving EU funding. However, as the governance structures of EU funds are complex and dynamic, municipalities are increasingly drawing on the knowledge and resources of ‘EU experts’ who mediate and provide project support. This article contributes to our understanding of how EU cohesion policy is translated through

Human papillomaviruses (HPVs) have evolved to use the DNA repair machinery to replicate its DNA genome in differentiated cells. HPV activates the DNA damage response (DDR) in infected cells. Cellular DDR factors are recruited to the HPV DNA genome and position the cellular DNA polymerase on the HPV DNA and progeny genomes are synthesized. Following HPV DNA replication, HPV late gene expression is

Increasingly, prostitution and other activities in the sex industries have been conceptualised as forms of labour, or at least as income-generating activities. As labour, these activities are exposed to particular risks with respect to health, working conditions, exploitation and stigmatisation. However, research on the actual conditions and circumstances existing in these markets, remains limited

We study the phase stability and martensitic transformation of orthorhombic and monoclinic polyethylene by means of density functional theory using the nonempirical consistent-exchange vdW-DF-cx functional [Phys. Rev. B 89, 035412 (2014)]. The results show that the orthorhombic phase is the most stable of the two. Owing to the occurrence of soft librational phonon modes, the monoclinic phase is pr

This article reflects on the role of the walking stick in the nineteenth-century city and explores the nature of the criticisms directed at it. The criticism and mocking of certain ways of holding the cane display the deep conflicts within the culture of urban strolling concerning how to take part in it, and who were allowed to do so. By identifying an irritation with canes, we see that there was

Aim: The impact of BL11282, an imidazoline receptor (NISCH) agonist, on potentiation of glucose-stimulated insulin secretion (GSIS) from isolated human non-diabetic (ND) and type 2 diabetic (T2D) islets was investigated. Methods: Analysis of mRNA was performed by RNA-sequencing and qPCR. Insulin and cAMP by RIA and ELISA respectively. Results: RNA-sequencing data revealed that NISCH is highly expr

Background: Few studies have focused on predictors of survival in patients with early-onset Alzheimer’s disease (EOAD) compared with late-onset Alzheimer’s disease (LOAD). We aimed to investigate the effect of genetic, sociodemographic, and clinical factors on mortality in the two groups.Methods: The Swedish Alzheimer Treatment Study (SATS) is a prospective, observational, multicenter study for lo

The majority of the power production in the world today is based on combustion of coal, oil and natural gas. Most countries have agreed that the amount of CO2 emitted to the atmosphere will have to be decreased to keep the global warming at sustainable levels. One way of reducing the CO2 emitted to the atmosphere is by introducing hydrogen co-firing. The hydrogen may be produced from renewable so

Tissue factor (TF) expressed at the protein level includes two isoforms: The membrane‑bound full‑length TF (flTF) and the soluble alternatively spliced TF (asTF). flTF is the major thrombogenic form of TF, whereas asTF is more closely associated with tumor growth, angiogenesis, metastasis and cell growth. In order to further investigate the different expression and functions of TF splice variants,

Comprehensive results on the production of unidentified charged particles, π±, K±, KS0, K∗(892)0, p, p, φ(1020), Λ, Λ, Ξ-, Ξ+, Ω-, and Ω+ hadrons in proton-proton (pp) collisions at s=7 TeV at midrapidity (|y|

Längs stränderna i Italien, Spanien och vid Öresund har vi alla hittat plastföremål som flyter i havet och ligger på stränderna. I Europa hamnar upp till en halv miljon ton plastavfall i haven varje år. Det motsvarar 66 000 sopbilar som dumpar sitt avfall direkt i havet istället för återvinningscentralen. Efter att frågan vuxit under de senaste åren har EU-länderna nu tagit upp kampen mot detta pr

BACKGROUND: Fetal/neonatal alloimmune thrombocytopenia (FNAIT) is the platelet counterpart of hemolytic disease of the newborn. Most severe cases of FNAIT are caused by antibodies against human platelet antigen-1a (HPA-1a). HPA-1a–negative women giving birth to an HPA-1a–positive child are at risk of becoming HPA-1a–immunized, particularly women who are HLA-DRB3*01:01–positive. The aim of the stud

While there is a huge literature on exchange rate systems since the classical gold standard, less research has been devoted to comparisons of the different arguments that guided the choices. While the origin of the international gold standard in the 1870s was a result of silver coins disappearing from circulation due to rising silver prices, the gold standard has later been interpreted as a quest

Artikel om den assyriska lobbningen vid fredskonferensen i Paris 1919.

Background Matrix metalloproteinases (MMP´s) are known biomarkers of atherosclerosis. MMP´s are also involved in the pathophysiological processes underlying chronic obstructive pulmonary disease (COPD). Cigarette smoking plays an important role in both disease states and is also known to affect the concentration and activity of MMP´s systemically. Unfortunately, the epidemiological data concerning

The secondary injury cascades exacerbating the initial brain injury following intracerebral haemorrhage (ICH) are incompletely understood. We used dual microdialysis (MD) catheters placed in the perihaemorrhagic zone (PHZ) and in seemingly normal cortex (SNX) at time of surgical ICH evacuation in ten patients (range 26-70 years). Routine interstitial MD markers (including glucose and the lactate/p

Understanding the carbon dynamics of the terrestrial biosphere during climate fluctuations is a prerequisite for any reliable modeling of the climate-carbon cycle feedback. We drive a terrestrial vegetation model with observed climate data to show that most of the fluctuations in atmospheric CO2 are consistent with the modeled shift in the balance between carbon uptake by terrestrial plants and ca

This article explores middle managers in the professions from their position in the sandwiched middle. Based upon interviews with senior academics in management roles and their subordinates in UK business schools, we investigate this experienced middle through a metaphor that informs one particular subject position: to be an umbrella carrier. This position entails protecting subordinates from what