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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 192494 sökträffar

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Purpose: Co-morbidities are common in chronic obstructive pulmonary disease (COPD) and are associated with increased morbidity and mortality. The aim of the present study was to explore the prevalence of several comorbid conditions in severe COPD, and to investigate and compare their associations with long-term mortality. Methods: In May 2011 to March 2012, 241 patients with COPD stage 3 or 4 were

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Having long been regarded as irrelevant to the high politics of foreign affairs, feminism and gender equality have in recent years gained increased attention in international security debates, including discussions about nuclear weapons policy. Several governments have adopted official feminist foreign policy postures, international security institutions have launched inquiries into gender equity

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The elliptic flow (v2) of D mesons from beauty-hadron decays (non-prompt D) was measured in midcentral (30–50%) Pb–Pb collisions at a centre-of-mass energy per nucleon pair sNN=5.02 TeV with the ALICE detector at the LHC. The D mesons were reconstructed at midrapidity (| y| < 0.8) from their hadronic decay D → K -π + , in the transverse momentum interval 2 < pT< 12 GeV/c. The result indicates a po

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This introductory chapter makes the case that despite different epistemological starting points, history and speculative fiction are both arguably “literatures of cognitive estrangement.” Both can help expose invisible problematic aspects of their authors’ and readers’ societies and suggest possible solutions or futures. Summarizing relevant existing literature and theoretical perspectives, the ch

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The Light Dark Matter eXperiment (LDMX) is an electron-beam fixed-target experiment designed to achieve comprehensive model independent sensitivity to dark matter particles in the sub-GeV mass region. An upgrade to the LCLS-II accelerator will increase the beam energy available to LDMX from 4 to 8 GeV. Using detailed GEANT4-based simulations, we investigate the effect of the increased beam energy

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Research on microplastics in Latin America is limited compared to a global perspective. Brazil plays a significant role in this context, as it possesses 12% of the world’s freshwater reserves, constituting 53% of South America’s water resources. There has been growing concern regarding the plastic pollution of the country’s freshwater systems in recent years. Therefore, this study investigated the

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The aim of this study was to explore university teachers’ perceptions of creative teaching and other factors that may influence academics’ efforts to teach creatively in higher education in Sweden. A qualitative case study was employed, interviewing 14 university teachers in three focus group interviews. The results show that the university teachers’ perceptions of creative teaching differed sligh

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Extracellular vesicles (EVs) play a crucial role in intercellular communication by transferring bioactive molecules from donor to recipient cells. As a result, EV fusion leads to the modulation of cellular functions and has an impact on both physiological and pathological processes in the recipient cell. This study explores the impact of EV fusion on cellular responses to inflammatory signaling. O

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This thesis embarks on a journey in the advancement of urban traffic management, centering around the innovative integration of Autonomous Intersection Management (AIM) systems. The research encompasses a comprehensive exploration of various facets of AIM implementation, significantly contributing to the evolution of a more efficient and safer urban transport system.The research investigates the d

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The induced polarization (IP) effect can be studied using both galvanic and inductive methods. Here we study IP and its manifestation in transient electromagnetic (TEM) data from a tTEM system and in time-domain electric resistivity tomography (ERT) data. Since the two methods are sensitive to two different frequency ranges, a direct IP spectrum comparison is not possible. Instead, we assess the I

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Background: Chest compression is a lifesaving intervention in out-of-hospital cardiac arrest (OHCA), but the optimal metrics to assess its quality have yet to be identified. The objective of this study was to investigate whether a new parameter, that is, the variability of the chest compression-generated transthoracic impedance (TTI), namely ImpCC, which measures the consistency of the chest compr

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Objective: The primary aim of this study was to examine the association between the different predicted phenotypes of the polymorphic CYP2D6 gene and the prevalence of adverse drug reactions in patients suffering from depressive disorders. The secondary aim was to investigate if comedication with CYP2D6 inhibitors resulted in more adverse drug reactions due to phenoconversion. Methods: Between Jan

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Background: Treatment of childhood glioma has evolved to reduce radiotherapy exposure with the goal of limiting late toxicity. However, the associations between treatment changes and neurocognition, and the contribution of neurocognition and chronic health conditions to attainment of adult independence, remain unknown. Methods: Adult survivors of childhood glioma diagnosed in 1970-1999 in the Chil

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Both inside and outside the academy, identifications of Islam as a terrorist threat have gained traction during the on-going War on Terror. William Cavanaugh’s conceptualization and critique of what he calls “the myth of religious violence” claims to offer a critique of these identifications. This critique has been influential across a variety of disciplines. In this article, I assess both his mor

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For theologians such as Karl Barth the support for Germany’s militaristic ambitions and actions voiced in the manifesto "An die Kulturwelt", published in 1914, was a consequence of the historicization of theology. Ernst Troeltsch (1865-1923), whose interdisciplinary thinking revolved around the significance of history for theology, was labeled the theologian of historicism. Although he had not sig