Sökresultat

Filtyp

Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 193324 sökträffar

No title

Herein, we contextualize, problematize, and offer some insights for moving beyond the problem of monolingual comparative normativity in (psycho) linguistic research on bilingualism. We argue that, in the vast majority of cases, juxtaposing (functional) monolinguals to bilinguals fails to offer what the comparison is supposedly intended to do: meet the standards of empirical control in line with th

No title

The test facility and synchrotron light source ANKA at the Karlsruhe Institute of Technology (KIT) operates in the energy range from 0.5 to 2.5 GeV and can generate brilliant coherent synchrotron radiation (CSR) in the THz range employing a dedicated bunch length-reducing optic at 1.3 GeV beam energy. The high degree of spatial compression leads to complex longitudinal dynamics and to time evolvin

No title

The aim of this position paper is to propose a reflection on how to account for and investigate the many ways in which interaction between robots and humans requires co-ordination, negotiation or reformulation of meanings emerging in the ongoing interaction. Towards this aim, we argue, a perspective shift may be needed: to frame interactions as social engagements whose meaning can only be understo

No title

Aim: Technology affects almost all aspects of modern eldercare. Ensuring ethical decision-making is essential as eldercare becomes more digital; each decision affects a patient’s life, self-esteem, health and wellness. Methods: We conducted a survey and interviews with eldercare professionals to better understand the behavioural ethics and decision making involved in the digital transition of elde

No title

(1) Background: The European Union Driver License Committee recently developed a questionnaire as a screening tool for obstructive sleep apnea (OSA), named the European Obstructive Sleep Apnea Screening (EUROSAS) questionnaire for drivers. The aim of the current study was to investigate the diagnostic performance of the EUROSAS to predict risk of OSA in professional male drivers. (2) Methods: Fift

No title

Urban form is consisting of several complex parameters which can affect urban microclimate in the energy calculations; most importantly the geometry of buildings, streets andcanopies. This study with a novel design-based approach generates 400 urban forms in the context of a dense urban area to evaluate the air flow and consequently the ventilation potential with the aids of CFD simulations in the

No title

Evidence-based design (EBD) for architecture involves the study of post-occupancy behaviour of building users with the aim to provide an empirical basis for improving building performance [Hamilton and Watkins 2009]. Within EBD, the high-level, qualitative analysis of the embodied visuo-locomotive experience of representative groups of building users (e.g., children, senior citizens, individuals f

No title

Background: The diagnosis and treatment of childhood acute lymphoblastic leukemia (ALL) may impact mental health. We investigated the long-term risk of psychiatric disorders among survivors of ALL in a population-based cohort study. Methods: We identified patients diagnosed with ALL in Denmark and Sweden before age 20 during 1982–2008. Survivors of ALL (n = 2026), their siblings (n = 3027), and po

No title

AIM: The study aimed to assess the haemodynamic effects of fludrocortisone and midodrine, alone or combined, in patients with recurrent syncope and/or symptoms due to hypotension and ≥ 1 daytime systolic blood pressure (SBP) drop < 90 mmHg or ≥ 2 daytime SBP drops < 100 mmHg recorded by 24-h ambulatory blood pressure monitoring (ABPM1).METHOD: A total of 53 patients (mean age, 40.9 ± 18.5 years, 3

No title

Ultra-thin high-Al content barrier layers can enable improved gate control and high-frequency operation of AlGaN/GaN high electron mobility transistors (HEMTs) but the precise composition control is very challenging. In this work, we investigate the compositional profiles of AlxGa1−xN/GaN HEMT structures with targeted Al content in the barrier layer, x = 0.50, 0.70, and 1, and thickness in the sub

No title

The blockade of the CD40/CD40L immune checkpoint is considered essential for cardiac xenotransplantation. However, it is still unclear which single antibody directed against CD40 or CD40L (CD154), or which combination of antibodies, is better at preventing organ rejection. For example, the high doses of antibody administered in previous experiments might not be feasible for the treatment of humans

No title

China’s rapid economic development has led to a continuously increasing energy demand and the country is the world’s biggest energy user as of today. The country accounts for around 23% of the global energy production, but 70% of the Chinese energy is generated with coal power and China is the biggest emitter of CO2 in the world. The Chinese government has set a couple of goals to reduce the count

No title

Apomorphine, given subcutaneously (s.c.), induces erection and bladder overactivity in rats through stimulation of dopamine (D1- and D2-like) receptors in the central nervous system. In paraplegic patients, apomorphine was reported to cause bladder overactivity. This suggests that apomorphine may have a spinal site of action also for stimulation of erection. The present study was initiated to eval

No title

Background: Ghrelin derives from endocrine cells (A-like cells) in the stomach (mainly the oxyntic mucosa). Its concentration in the circulation increases during fasting and decreases upon re-feeding. This has fostered the notion that the absence of food in the upper gastrointestinal (GI) tract stimulates the secretion of ghrelin. The purpose of the present study was to determine the concentration

No title

We have studied the effects of bulk anisotropy and the strain induced by lattice mismatch on the interband tunneling in broken-gap single-barrier InAs/AlSb/GaSb heterostructures and double-barrier InAs/AlSb/GaSb/InAs/AlSb/GaSb heterostructures. We have used the eight-band k.p model and the scattering matrix method, combined with the Burt envelope function theory, to calculate the interband transmi

No title

Mice with allergically inflamed airways are widely used as animal models of asthma, but their relevance for human asthma is not understood. We, therefore, examined the time course of changes in respiratory input impedance during induced bronchoconstriction in BALB/c mice sensitized and challenged with ovalbumin. Our results indicate that bronchoconstriction in mice is accompanied by complete closu

No title

Natural antibodies (NAbs) constitute an important component in vertebrate immune system, but, in spite of this, have often been dismissed as "non-specific background" signals. We observed a significant positive relationship between water python (Liasis fuscus) body length/age and levels of antibodies reactive with two administered antigens (tetanus and diphtheria). However, no humoral immune respo