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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 192517 sökträffar

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We consider random graphs on the set of N2 vertices placed on the discrete 2-dimensional torus. The edges between pairs of vertices are independent, and their probabilities decay with the distance ρ between these vertices as (Nρ)−1. This is a versatile example of an inhomogeneous random graph that is not of rank 1. Here, we study the critical phase: the main result is the weak limit of the size of

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BACKGROUND AND OBJECTIVE: BRCA1 and BRCA2 pathogenic germline variants (PGVs) are associated with higher risk of prostate cancer (PC). The IMPACT study evaluated the utility of targeted prostate-specific antigen (PSA) screening in BRCA1/BRCA2 PGV carriers. Here we report outcomes after five rounds of PSA screening in IMPACT.METHODS: Between 2005 and 2015, 3063 participants aged 40-69 yr (median 54

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The context of armed conflict situations presents unique challenges that can compromise the safety and well-being of both affected populations and responders in radiological and nuclear emergencies. The focus of the EU project RRADEW ‘Resilience to RADiological Events in Wartime’ (2024–2027) is to enhance nuclear Emergency Preparedness, Response and Recovery (EPR&R) systems by strengthening re

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Study region: Trelleborg is a mid-sized coastal municipality in southern Sweden that has experienced repeated pluvial flooding in recent decades. The city comprises areas served by both combined and separate sewer systems and is increasingly exposed to intense short-duration rainfall events. This study uses 17 years (2006–2023) of property-level flood reports, in situ rainfall observations from mu

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The transition to post-quantum cryptography is well underway. Driven by the recognition that Shor's algorithm would render all widely deployed asymmetric cryptosystems insecure in the presence of a sufficiently capable quantum computer, the cryptographic community has spent the past decade designing, evaluating, and standardizing a new generation of public-key primitives. In 2024, ML-KEM became th

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In communication and management research, coworker voice has been widely acknowledged as a central component for organizations’ long-term development and survival. With the increasing digitalization and need for flexibility, digital workplace meetings have become a common form of communication, demonstrating a new arena where coworker voice is expressed and shaped. Thus, the aim of this study is t

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We employ small-angle x-ray and dynamic light scattering to investigate the microscopic structure and dynamics of dense suspensions of ultra-low crosslinked (ULC) poly(N-isopropylacrylamide) microgels. By probing the supercooled and glassy regimes, we characterize the relationship between the structure and dynamics as a function of effective volume fraction φ and probed length scale. We demonstrat

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The amyloid precursor protein intracellular domain (AICD) is an intrinsically disordered regulatory segment whose conserved YENPTY motif mediates transient interactions with multiple adaptor and signaling proteins. How sequence perturbations within this motif modulate its accessibility and interaction potential within a disordered ensemble remains poorly understood. Here, we combine small-angle X-

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The combined use of waste heat (WH), ground-source heat pumps (GSHPs), and district heating (DH) offers an effective pathway to decarbonize urban heating. Taking a system-integration perspective, this review synthesizes technical, operational, and policy dimensions of WH-assisted GSHPs coupled to DH. Both centralized and decentralized configurations are examined, focusing on thermal energy storage

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Identifying high-temperature unconventional charge order and superconductivity in kagome systems is crucial for understanding frustrated, correlated electrons and enabling future quantum technologies. Here, we report that the kagome superconductor YRu3Si2 hosts an exceptional interplay of charge order, magnetism, and superconductivity, revealed through a comprehensive suite of muon spin rotation (

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The rapid development of China's outbound tourism in European countries is receiving more and more attention from the European tourism industry. The improvements of the national economy, the characteristics of Chinese culture and the strengthening of the economic and cultural bonds between China and European Union countries have all played roles in its growth. This master thesis summarizes Chi

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For the last three decades, many things have changed around us. New businesses have grown up and new fields have emerged. One such field is video games which are liked by children. There is already research, which proves that children often like to play violent games which affect their personality and make their behavior violent (Rathus, 2004; Anderson & Dill, 2000; Crawford, 2003; Walsh, 2001

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This study examines China’s future energy trend by analyzing how the energy demand in China has changed and how it will change by looking at several domestic factors, such as structural and policy changes, as well as international factors that affect the country’s demand for energy. The sector-specific energy consumption trend in the near future is also discussed in order to show what the main dri

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Reducing the risk exposure in investment portfolios is a constant topic in financial literature. This thesis aims to discuss and compare the risk level in portfolios of only Eastern or only Western European market indices by studying the correlation within each one of the portfolios. The correlation is estimated with two different methods: the traditional time-series and Solnik and Roulet’s (2000)

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Abstract The subject of this thesis is introduction of competition in public services and its effects on public sector efficiency generally, and the Swedish compulsory school specifically. The issue is studied in a theoretical framework of institutional and transaction cost theory. A concentration ratio competition measure is developed, covering public and private competition, as well as competiti

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This thesis is about how these small farmers in two socio-ecological systems in southern Ecuador accommodate their agro-ecologies and gender systems to national and international forces and networks, and how it relates to processes of ecological appropriation conflictive with their possibilities of wellbeing. Loja, in the Southern Ecuadorian Andes, maize growers embrace industrial production, with

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This study aimed at exploring the understandings of financial partnerships among local non-governmental development organizations (LNGDOs) and donors in Cameroon. Research took place in Yaounde and the North-West Region in November and December 2010. Qualitative interviews with LNGDOs, donors and key informants as well as two focus groups have served as main data source. Analytically, the concepts