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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 192508 sökträffar

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The delivery of emulsified silicone oil to hydrophilic silica surfaces by mixtures of cationic polysaccharides and SDS has been studied by in situ null ellipsometry, dynamic light scattering, and turbidity measurements. The emulsion contained silicone oil droplets with a hydrodynamic radius of 18 rim, stabilized by anionic and nonionic surfactants. The investigated polysaccharides were cat-guar an

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A novel molecularly imprinted polymer (MIP) powder designed for the selective removal of interfering chlorophyll pigment from heavily pigmented green plant extracts during pesticide residue analysis or analysis for bioactives in natural product research is reported. The polymer powder imprinted with chlorophyll.. was synthesized by copolymerizing the functional and cross-linking monomers, methacry

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Ultrafast time-resolved fluorescence spectroscopy has been used to investigate the excited-state dynamics of the basic eumelanin building block 5,6-dihydroxyindole-2-carboxylic acid (DHICA), its acetylated, methylated, and carboxylic ester derivatives, and two oligomers, a dimer and a trimer in the O-acetylated forms. The results show that (1) excited-state decays are faster for the trimer relativ

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A thermostable glycoside hydrolase family-10 xylanase originating from Rhodothermus marinus was cloned and expressed in the methylotrophic yeast Pichia pastoris (SMD1168H). The DNA sequence from Rmxyn10A encoding the xylanase catalytic module was PCR-amplified and cloned in frame with the Saccharomyces cerevisiae alpha-factor secretion signal under the control of the alcohol oxidase (AOX1) promoto

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Purpose: A scale assessing primary care physicians' priorities for genetic education (The Gen-EP scale) was developed and tested in five European countries. The objective of this study was to determine its factor structure, to test scaling assumptions and to determine internal consistency. Methods: The sample consisted of 3686 practitioners (general practitioners, gyneco-obstetricians, pediatricia

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Study objectives: In 1996, researchers in Sweden initiated a collaborative randomized study comparing lung volume reduction surgery (LVRS) and physical training with physical training alone. The primary end point was health status; secondary end points included survival and physiologic measurements. Design: After an initial 6-week physical training program, researchers' patients were randomized to

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Background There have been few studies evaluating patient-reported quality of life outcomes after hip revision with impaction bone grafting. Patients and methods The inclusion criteria were aseptic loosening after primary arthroplasty performed for osteoarthrosis, and first-time revision with impacted morselized allograft bone and cemented Exeter stem. During a 4-year period, 35 patients were elig

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The prediction of transcription factor binding sites in genomic sequences is in principle very useful to identify upstream regulatory factors. However, when applying this concept to genomes of multicellular organisms such as mammals, one has to deal with a large number of false positive predictions since many transcription factor genes are only expressed in specific tissues or cell types. We devel

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In this study we retrieved the spatial distribution of mid-afternoon clouds under various synoptic regimes across the Iberian Peninsula and the Balearic Islands for the warm/convective-season, from May to October. Accurate daily cloud masks were derived by applying a daytime over land multispectral convective cloud detection algorithm spanning 15 years (1997–2011) of Advanced Very High Resolution

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OBJECTIVES: To map by magnetic resonance imaging (MRI) and quantitative MRI (qMRI) concomitant fractures and meniscal injuries, and location and volume of traumatic bone marrow lesions (BMLs) in the acutely anterior cruciate ligament (ACL) injured knee. To relate BML location and volume to cortical depression fractures, meniscal injuries and patient characteristics. METHODS: One hundred and twenty

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In 2000, the Clinton Administration in the U.S. adopted the Commodity Futures Modernization Act, which deregulated the U.S. trade with financial instruments on commodity markets. With respect to this adoption, it has been regarded as one catalyst for the Global food crisis 2008, where millions of individuals lacked provision and access to agricultural products and nutrition. From the perspective o

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De senaste åren har beskattning av den digitala ekonomin hamnat i focus. Det har gett upphov till att bl.a. OECD och EU har kommit med förslag på hur man ska kunna lösa detta dilemma. Traditionellt blir ett företag beskattat i den stat där detta har hemvist eller i den stat där företaget har ett fast driftställe för vilket det är angivet flera olika anknytningspunkter. Dessa anknytningsfaktorer byIn the last couple of years, taxation of the digital economy has become a subject that is on everybody’s mind. This has given rise to attempts from OECD and EU, amongst others, to solve this dilemma. For a company to be taxed in a state it must be a resident in that state or be attributed a permanent establishment that requires that the company has a physical presence in the state. This makes taxi

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The Nucleosome Remodeling and Deacetylase (NuRD) complex is a transcriptional regulator essential to several normal developmental processes, but also found to have a role in several types of cancer. In order to design cancer therapies targeting this complex, determining the structure and subunit composition is crucial. X-ray crystallography is required for the level of detail desired, demanding la

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Denna studie undersökte ungdomars erfarenheter av viktmobbning i en svensk skolkontext, samt hur ungdomar upplever skolans strategier för att hantera viktmobbning och vilka insatser de önskar att skolan hade vidtagit. Eftersom tidigare forskning som fokuserar på själva upplevelsen av viktmobbning är begränsad, gjordes en explorativ kvalitativ studie där en kritisk realistisk position intogs för atThe aim of this study was to investigate adolescents’ experiences of weight- related bullying in a Swedish school context, how they experience the schools’ strategies for weight-related bullying and which actions they wished the schools had taken. Since previous research on the subject is limited, an explorative qualitative study was conducted in which a critical realist position was adopted. The

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In this master thesis a novel way of trapping nanosized particles were tested. The technology used was based on acoustic trapping with seed particles. In difference to earlier devices the seed particles were held in place by a physical barrier that worked like a filter, stopping the bigger seed particles while allowing the nanosized particles to flow through, a setup that allowed for significantly

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As the physical consequences of climate change continues to augment, possibly millions of people might be forced to migrate. Those most likely to be forced to move are people living in poor countries in the Global South where vulnerability levels are generally high and the capacity to adapt is often low due to socio-economic difficulties and political insecurity. In contrast, the countries most re

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Problem: Literature yields ambiguous results regarding the effectiveness of the business incubators’ role as network intermediaries, which is reflected in the varying networking behavior of entrepreneurs. Network expectations as a driver for the networking behavior of entrepreneurs have not been studied within this context and present a void in current literature. Purpose: This study seeks to exp

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Pokémon Go is a Pokémon theme smartphone game released in July, 2016. The game surprisingly created a global boom of ‘Pokémon Go gaming engagement’ during the second half of 2016. This thesis is interested in the phenomenon, and wants to investigate how the factors including the technology of augmented reality (AR) impact the gaming experience and drive the gaming engagement in this case. The rese

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American consumption based lifestyles have a grave impact on the environment and personal wellbeing of Americans, creating unhealthy consumption patterns, unforeseen negative effects on individuals, and ultimately unsustainable lifestyles overall. Voluntary simplicity (VS), or individuals who resist consumerist tendencies seeking a higher quality of life through simplicity, is an answer to these c