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This dissertation is developed against the background of globalisation and the rise of a new type of instrument used to deal with the accompanying developments. These instruments are designated by the present dissertation as global framework agreements (GFAs). They constitute a written compromise, signed between global union federations and multinational enterprises, setting rights-based minimum s
Even though energy-efficient technologies are well developed, the behaviour of building occupants plays an important role in the search for the optimum level of energy efficiency. In academic literature, however, very few studies have used psychological theories to understand individuals’ drivers of energy use behaviour when interacting with energy-efficient technologies. Specifically, there are n
Children with left heart disease are at risk for developing pulmonary hypertension, initially secondary to pulmonary venous hypertension that can progress to include elevated pulmonary vascular resistance, known as combined pre- and postcapillary pulmonary hypertension. Elevated pulmonary vascular resistance may pose a risk to the right ventricle of a newly transplanted heart because of increased
In Verbal Aspect in Synoptic Parallels Wally Cirafesi answers the question of why the Synoptic Gospels at times employ different tense-forms to communicate the same action. The problem has typically been explained from the perspective of redaction criticism and temporal Aktionsart approaches to the Greek verb. Cirafesi challenges these approaches by reframing the discussion in terms of recent adva
This article deals with the image-making of Swedish monarchs in the decades preceding and succeeding the Swedish Revolutionary Year of 1809, a year witnessing the dethronement of a king and the composition of a new constitution. In this era, the monarchies of Europe faced a great challenge in accommodating conflicting ideals of the Ancien Régime and of emergent bourgeois civic society. In dynastic
OBJECTIVE: To describe and examine potential predictors of changes in pain and disability in patients with shoulder pain who have completed 3 months of digitally delivered treatment comprising exercise and patient education.DESIGN: Retrospective cohort study (clinicaltrials.org Nr: NCT05402514).SUBJECTS: Patients with shoulder pain who completed treatment (n = 682).METHODS: Primary outcome was cha
Purpose: To evaluate the feasibility of a 3-minutes protocol for assessment of the microscopic anisotropy and tissue heterogeneity based on tensor-valued diffusion MRI in a wide range of intracranial tumors. Methods: B-tensor encoding was performed in 42 patients with intracranial tumors (gliomas, meningiomas, adenomas, and metastases). Microscopic anisotropy and tissue heterogeneity were evaluate
AIMS: Using functional magnetic resonance imaging (fMRI) we investigated the cortical and subcortical representations during bladder filling and the effect of simultaneous stimulation of the dorsal clitoral nerve on these cortical and subcortical structures.METHODS: After approval of the local ethics committee, 8 healthy females were included. Prior to scanning, subjects were catheterized and the
Tissue patterning during development is thought to be driven largely by gene regulatory responses to spatial gradients of molecular signals, known as morphogens. In this thesis, early patterning of the human neural tube is studied using two different gene regulatory network models. The models portray patterning in the rostral-caudal direction as a response to gradients of WNT and FGF signalling. T
OBJECTIVE: Patients with extensive and long-standing ulcerative colitis have an increased risk of developing colorectal cancer and sub-epithelial fibrosis. The polypeptide transforming growth factor alpha (TGF-alpha) has mitogenic effects and it is believed that local overproduction may result in tumour formation and fibrosis. DESIGN: In the present study, we correlated the presence of TGF-alpha i
The aim of the present study was to investigate the distribution of suicide attempts across the depressive episodes in suicides and controls with a severe depression. A blind record evaluation was performed of 100 suicide victims and matched controls admitted to the Department of Psychiatry between 1956 and 1969 and monitored to 2006. There was a similar number of episodes in suicides and controls
Understanding tree recruitment is needed to forecast future forest distribution. Many studies have reported the relevant ecological factors that affect recruitment success in trees, but the potential for genetic-based differences in recruitment has often been neglected. In this study, we established a semi-natural reciprocal sowing experiment to test for local adaptation and microenvironment effec
Tyler, G. 2010: Variability in colour, metallic lustre, and body size of Carabus arvensis Herbst, 1784 (Coleoptera: Carabidae) in relation to habitat properties.-Entomol. Fennica 21: 90-96. Objectives are to elucidate whether populations of Carabus arvensis Herbst, 1784 from contrasting habitats differ in (i) colour, (ii) brightness of metal lustre, or (iii) body size (length of elytra, of elytra
Cell therapy for Parkinson's disease (PD) is based on the idea that new midbrain dopamine (mDA) neurons, implanted directly into the brain of the patient, can structurally and functionally replace those lost to the disease. Clinical trials have provided proof-of-principle that the grafted mDA neurons can survive and function after implantation in order to provide sustained improvement in motor fun
PURPOSE: To describe new disease-causing RP2 and RPGR-ORF15 mutations and their corresponding clinical phenotypes in Swedish families with X-linked retinitis pigmentosa (XLRP) and to establish genotype-phenotype correlations by studying the clinical spectrum of disease in families with a known molecular defect. METHODS: Seventeen unrelated families with RP and an apparent X-linked pattern of disea
