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This thesis investigates the relationship between regional disparities and the employment outcomes of Technical and Vocational Education and Training (TVET) graduates in Kenya, using logistic and ordinal logistic regression models. Drawing on nationally representative survey data and regional indicators, such as gross county product (GCP) per capita, urbanization rates and development expenditure,
This paper examines relocation of taxpayers during 2000 to 2021 across Swedish local work regions and its implications on the tax system. There exist 290 mu- nicipalities in Sweden, which are divided into 67 local work regions. Relocation is categorised as either relocation within or outside local work regions. Furthermore, a distinction is made between age and income groups in order to capture po
Inspired by the experimental work performed in the research group led by Ville Maisi at Lund University, this thesis investigates a hybrid quantum setup in circuit quantum electrodynamics (cQED). The system consists of a microwave resonator coupled to a double quantum dot (DQD) acting as an internal sensor to indirectly detect the state of an external quantum system. Using input-output theory and
Secondary hyperparathyroidism is a common condition in patients with end-stage renal disease and is associated with osteoporosis and cardiovascular disease. Despite improved medical treatment, parathyroidectomy (PTX) is still necessary for many patients on renal replacement therapy. The aim of this study was to evaluate the effect of PTX on patient survival.
Vision is the primary sensory modality of birds, and its importance is evident in the sophistication of their visual systems. Coloured oil droplets in the cone photoreceptors represent an adaptation in the avian retina, acting as long-pass colour filters. However, we currently lack understanding of how the optical properties and morphology of component structures (e.g. oil droplet, mitochondrial e
Next-generation sequencing of the V1-V2 and V3 variable regions of the 16S rRNA gene generated a total of 674,116 reads that described six distinct bacterial biofilm communities from both water meters and pipes. A high degree of reproducibility was demonstrated for the experimental and analytical work-flow by analyzing the communities present in parallel water meters, the rare occurrence of biolog
Many ectothermic species are currently expanding their distributions polewards due to anthropogenic global warming. Molecular genetic mechanisms facilitating range expansion under these conditions are largely unknown, but understanding these could help mitigate expanding pests and disease vectors, or help explain why some species fail to track changing climates. Here, using RNA-seq data, we examin
Obesity is a highly prevalent complex trait that raises the risk of other chronic diseases such as type 2 diabetes, certain cancers, sleep apnea, and cardiovascular disease, and shortens lifespan. Clinical intervention studies focused on weight loss and epidemiological studies of obesity indicate that genetic variation may modify the relationship between lifestyle behaviors and weight loss or weig
cAMP-response element-binding protein (CREB) is required for the induction of adipogenic transcription factors such as CCAAT/enhancer-binding proteins (C/EBPs). Interestingly, it is known from other tissues that LKB1 and its substrates AMP-activated protein kinase (AMPK) and salt-inducible kinases (SIKs), negatively regulate gene expression by phosphorylating the CREB co-activator CRTC2 and class
Synapsins are a family of phosphoproteins that modulate the release of neurotransmitters from synaptic vesicles. The release of insulin from pancreatic beta-cells has also been suggested to be regulated by synapsins. In this study, we have utilized a knock out mouse model with general disruptions of the synapsin I and II genes [synapsin double knockout (DKO)]. Stimulation with 20 mM glucose increa
Some developments of nuclear-structure physics uniquely related to Copenhagen School are sketched based on theoretical considerations versus experimental findings and one-particle versus collective aspects. Based on my personal overview I pick up the following topics; (1) Study of vibration in terms of particle-vibration coupling; (2) one-particle motion in deformed and rotating potentials, and yr
Low-frequency coding DNA sequence variants in the proprotein convertase subtilisin/kexin type 9 gene (PCSK9) lower plasma low-density lipoprotein cholesterol (LDL-C), protect against risk of coronary heart disease (CHD), and have prompted the development of a new class of therapeutics. It is uncertain whether the PCSK9 example represents a paradigm or an isolated exception. We used the "Exome Arra
Volatile organic compounds (VOCs) may be emitted from surfaces indoors leading to compromised air quality. This study scrutinized the influence of relative humidity (RH) on VOC concentrations in a building that had been subjected to water damage. While air samplings in a damp room at low RH (21-22 %) only revealed minor amounts of 2-ethylhexanol (3 μg/m(3)) and 2,2,4-trimethyl-1,3-pentanediol diis
The understanding of multiple bubbles condensation is of significant importance in developing continuum models for the large-scale subcooled flow boiling. The computational fluid dynamics (CFD) modeling for multiple bubbles condensation is developed with the volume of fluid (VOF) method in this work. An explicit transient simulation is performed to solve the governing equations including the sourc
Immunoglobulin A (IgA) nephropathy is a chronic glomerulonephritis with excessive glomerular deposition of IgA1, C3 and C5b-9, which may lead to renal failure.
The Tibetan highlands host the largest alpine grassland ecosystems worldwide, bearing soils that store substantial stocks of carbon (C) that are very sensitive to land use changes. This study focuses on the cycling of photoassimilated C within a Kobresia pygmaea pasture, the dominating ecosystems on the Tibetan highlands. We investigated short-term effects of grazing cessation and the role of the
Secretion of outer membrane vesicles (OMV) is an intriguing phenomenon of Gram-negative bacteria and has been suggested to play a role as virulence factors. The respiratory pathogens Moraxella catarrhalis reside in tonsils adjacent to B cells, and we have previously shown that M. catarrhalis induce a T cell independent B cell response by the immunoglobulin (Ig) D-binding superantigen MID. Here we
The 12-item Short-Form Health Survey (SF-12) is an abbreviated version of the SF-36, one of the most widely used patient-reported health outcome rating scales. Similar to the SF-36, it yields summary scores of physical and mental health (PCS and MCS, respectively). However, SF-36 derived PCS and MCS scores have not been found valid in neurological disorders such as Parkinson's disease (PD). Here w
