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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 194653 sökträffar

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The transition rates of the intercombination lines 2s2p(3 5)S(2)(0)-->2s(2)2p(2 3)P(1,2) are computed using a systematic configuration interaction method (SCIV3). The calculated lifetime of the upper S-5(2)o, level is in excellent agreement with a recent experiment. The branching ratio of the two lines is very different from earlier, less accurate theoretical values.

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Proteins and peptides in bovine milk and colostrum were separated by two-dimensional gel electrophoresis (2-DE). The proteins were separated in the first dimension by isoelectric focusing in the pH ranges 4-7 and 6-11, and in the second dimension by sodium dodecyl sulphate polyacrylamide gel electrophoresis on 12.5% T homogeneous gels. The peptides were separated in the pH range 3-10 in the first

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Objective To investigate whether venous Doppler velocimetric signs of cardiac decompensation might predict fetal demise in severely compromised fetuses. Material and methods This was a prospective study involving 154 growth-restricted fetuses, 37 of which were found to have reversed flow in the umbilical artery (BFC III). Doppler velocimetry of the right hepatic vein and ductus venosus were invest

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The vapour-liquid partition of various VOC (Volatile Organic Compounds) in a number of industrial black liquors was investigated. The information can be used to determine the distribution of VOC in different condensate and gas streams in a kraft mill. Batchwise evaporation of weak black liquors was performed on a lab scale. The evaporation was carried out at atmospheric pressure up to over 90% dry

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Background: TNF alpha is a cytokine that may contribute to the pathophysiology of airway inflammation. Inhalation of TNF alpha produces granulocyte recruitment and airway hyperresponsiveness in man. Anti-TNF alpha treatment may inhibit allergen-induced plasma exudation in guinea-pig airways. Increased nasal mucosal output of TNF alpha has been demonstrated in allergic rhinitis, but the effect of T

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The degradation of technical toxaphene in water with two kinds of bioreactors operating in sequence was studied. One packed bed reactor was filled with Poraver(R) (foam glass particles) running at anaerobic conditions and one suspended carrier biofilm reactor working aerobically. Chemical oxygen demand (COD), chloride, sulphate, pH, dissolved oxygen, total toxaphene and specific toxaphene isomers

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Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors regulating the expression of genes involved in lipid and glucose metabolism in a complex and to some extent unknown manner. Our aim was to study the impact of different factors on PPAR delta mRNA expression in human skeletal muscle on one side, and the impact of PPAR delta mRNA expression on these factors, including glucose

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Many small passerines are resident in forests with very cold winters. Considering their size and the adverse conditions, this is a remarkable feat that requires optimal energy management in several respects, for example regulation of body fat reserves, food hoarding and night-time hypothermia. Besides their beneficial effect on survival, these behaviours also entail various costs. The scenario is

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In today's world, there is an increasing trend towards the use of renewable, cheap and readily available biomass in the production of a wide variety of fine and bulk chemicals in different biorefineries. Biorefineries utilize the activities of microbial cells and their enzymes to convert biomass into target products. Many of these processes require enzymes which are operationally stable at high te

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All service control nodes, for example Web sites or Mobile Switching Centers, can be modeled as server systems with one or more servers processing the incoming requests. To avoid overload at the service control node different types of admission control mechanisms are usually implemented. In this paper we discuss, from a control point of view, the modeling of a service control-node. The queue is as

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The interaction between localized and extended vibrational modes in solids is of central importance in understanding how local vibrational modes (LVMs) decay into phonons. In this study, we have investigated interstitial oxygen (O-i) in silicon as a model 'laboratory' for such local-extended mode interactions. Using hydrostatic pressure and infrared spectroscopy, we brought the stretch mode of O-1

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Aquaporins are water channel proteins that facilitate the movement of water and other small solutes across biological membranes. Plants usually have large aquaporin families, providing them with many ways to regulate the water transport. Some aquaporins are regulated post-translationally by phosphorylation. We have previously shown that the water channel activity of SoP1P2;1, an aquaporin in the p

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Pancreatic tissue grafting is by far the most physiological therapeutic solution to the insulin deficiency of diabetes. Recent clinical trials have indicated somewhat successful use of nonsteroidal immunosuppressive regimens and a successful nonhuman primate trial using CD154 for costimulation blockade was reported. However, these protocols need to be replaced with safe and efficacious ones in whi

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A general formalism is presented for the interpretation of experiments in which a laser pulse (or pump pulse) creates charge carriers that are subsequently probed by a broadband THz pulse (or probe pulse). The time dependence of the sample properties is described in terms of the conductivity (,), where the dependence on frequency describes the intrinsic properties of the charge carriers and the de

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Hypoglycemic sulfonylureas represent a group of clinically useful antidiabetic compounds that stimulate insulin secretion from pancreatic beta cells. The molecular mechanisms involved are not fully understood but are believed to involve inhibition of potassium channels sensitive to adenosine triphosphate (KATP channels) in the beta cell membrane, causing membrane depolarization, calcium influx, an

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Two superdeformed (SD) bands extending over eight to eleven transitions have been identified in Zr-83, The quadrupole moment of the more intense band was determined by the Residual Doppler Shift Method and is consistent with a quadrupole deformation of beta(2) approximate to 0.5. The large quadrupole moment and population intensity of the yrast SD band (approximate to 5%) in Zr isotopes relative t

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This thesis consists of five papers (A-E). In Paper A, we study transient properties of the queue length process in various queueing settings. We focus on computing the mean and the Laplace transform of the time required for the queue length starting at $x