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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 113971 sökträffar

Lymphedema and Health-Related Quality of Life

Lymfödem är en svullnad som kan uppkomma i olika delar av kroppen. Svullnaden uppstår på grund av att lymfvätska inte hinner dräneras bort i tillräcklig takt, utan blir kvar i vävnaden. Orsaken kan vara en medfödd genetisk svaghet i lymfsystemet alternativt en skada på lymfsystemet orsakat av operation, infektion, inflammation eller annan kroppskada. Vanligast i Sverige är lymfödem i arm eller benThe overall aim of this thesis was to develop a lymphedema-specific instrument for measuring health-related quality of life (HRQoL) and to evaluate how persons with lymphedema experience HRQoL. Lymphedema is defined as swelling in one or more parts of the body that is due to impaired lymph drainage and transport. The impairments in the lymph system can be congenital or secondary to, e.g., cancer t

Time-Dependent Proteomic iTRAQ Analysis of Nasal Lavage of Hairdressers Challenged by Persulfate.

Hairdressers are frequently exposed to bleaching powder containing persulfates, a group of compounds that may induce hypersensitivity in the airways. The mechanism causing this reaction is not clear. The aim of this study was to identify changes in the nasal lavage fluid proteome after challenge with potassium persulfate in hairdressers with bleaching powder-associated rhinitis. Furthermore, we ai

The influence of different technique factors on image quality of lumbar spine radiographs as evaluated by established CEC image criteria

In this study we have investigated the image quality of lumbar spine radiographs taken after recording technical and physical parameters. Two technical parameters were altered, tube voltage (70 kV and 90 kV for the anteroposterior (AP) projection and 77 kV and 95 kV for the lateral projection) and sensitivity of the film-screen system (sensitivity class 400 and 600). In total, 85 images were inclu

Effects of 2,3-butanedione monoxime on activation of contraction and crossbridge kinetics in intact and chemically skinned smooth muscle fibres from guinea pig taenia coli

The effects of 2,3-butanedione monoxime (BDM) were studied in smooth muscle fibres from guinea pig taenia coli. In intact muscle, active force during contractions induced by high-K+ was inhibited by about 10% in 1 mM BDM and by approximately 70% in 10 mM BDM. Intracellular [Ca2+] during contraction, measured with the fura-2 technique, was reduced in the presence of BDM. The reduction in force and

Agarose-coated anion exchanger prevents cell-adsorbent interactions

A common problem during recovery of bioproducts by adsorption from particulate broths is fouling of the adsorbent material as a result of the interaction of cells and cell debris, which present negative charges, with the positively charged anion exchangers commonly used in bioprocesses. The effect of shielding an adsorbent with a layer of agarose on reducing the binding of cells while still allowi

MUC4 Is a Highly Sensitive and Specific Marker for Low-grade Fibromyxoid Sarcoma.

Low-grade fibromyxoid sarcoma (LGFMS) is a distinctive fibroblastic neoplasm that is characterized by alternating collagenous and myxoid areas, deceptively bland spindle cell morphology, a whorling architecture, and a t(7;16) translocation involving FUS and CREB3L2. Owing to variable morphology and a lack of discriminatory markers, LGFMS can be difficult to distinguish from benign mesenchymal tumo

Wireless Esophageal pH Monitoring in Children.

ABSTRACT Introduction: A wireless BRAVO() (Medtronic, Shoreview, MN) capsule for pH measurement in the diagnosis of gastroesophageal reflux disease (GERD) is intended to be less uncomfortable, and facilitates activity during the measuring period, compared to the usual method with a naso-esophageal catheter. The aim of this study was to report on our experience with the wireless system in children.

Mutation screening of the RYR1-cDNA from peripheral B-lymphocytes in 15 Swedish malignant hyperthermia index cases.

BACKGROUND: Malignant hyperthermia (MH), linked to the ryanodine receptor 1 gene (RYR1) on chromosome 19, is a potentially lethal pharmacogenetic disorder which may lead to a disturbance of intracellular calcium homeostasis when susceptible individuals are exposed to halogenated anaesthetics, suxamethonium, or both. Central core disease (CCD) is a rare dominantly inherited congenital myopathy alle

Prevalence of zinc transporter 8 antibodies in gestational diabetes mellitus.

Aims: Gestational diabetes mellitus affects approximately 7% of all pregnant women. Some of these women develop autoantibodies that are generally characteristic of Type 1 diabetes. Autoantibodies targeting glutamic acid decarboxylase and tyrosine phosphatase-like protein are the most frequently reported. A recently identified autoantigen in Type 1 diabetes is zinc transporter 8. Some reports sugg

Coping strategies and health symptoms among women and men in a downsizing organisation

This study examined how women and men cope with stress during a period of organisational change and how the coping strategies are related to health. Questionnaire responses were obtained from 98 female and male administrators of health care service working in a Swedish governmental County Council during a period of downsizing. In line with earlier studies the results showed women to be more likely

Short- and midterm results of the fascia suture technique for closure of femoral artery access sites after endovascular aneurysm repair.

Abstract Purpose: To evaluate the midterm outcomes and potential risk factors associated with the fascia suture technique (FST) for closure of femoral artery access sites after percutaneous endovascular aneurysm repair (EVAR). Methods: Between April 2007 and April 2008, 100 consecutive EVAR cases were evaluated retrospectively. A third of the procedures were emergent (16 ruptured aneurysms). Of th

The Making of the Modern World

This is a chapter I wrote for a book, International Relations: A Beginner's Guide, edited by Stephen McGlinchey and forthcoming with E-International Relations Publishing in January 2017. It is my attempt to describe the origin of the state, and the European interstate system, as they came to develop from the Middle Ages onwards, and also to say something about how the European system spread to the