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We have evaluated a method for synthesizing mammograms by comparing the texture of clinical and synthetic mammograms. The synthesis algorithm is based upon simulations of breast tissue and the mammographic imaging process. Mammogram texture was synthesized by projections of simulated adipose tissue compartments. It was hypothesized that the synthetic and clinical texture have similar properties, a
Spontaneous formation of vesicles from the self-assembly of two specific surfactants, one zwitterionic (oleyl amidopropyl betaine, OAPB) and the other anionic (Aerosol-OT, AOT), is explored in water using small-angle scattering techniques. Two factors were found to be critical in the formation of vesicles: surfactant ratio, as AOT concentrations less than equimolar with OAPB result in cylindrical
Introduction: Renography is a standard diagnostic examination that evaluates renal function, renal pelvic dilatation and urinary obstruction. Renography is performed by injecting a radiopharmaceutical (predominately 99mTc-MAG3) and using gamma camera to image the biodistribution in a dynamic sequence. Evaluating renography images encompasses many difficulties regarding background correction for ac
3D-odlade celler ger bättre bild av verkligheten – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök 3D-odlade celler ger bättre bild av verkligheten 2022-11-04 Hur tränger virus in i och förökar sig i våra celler? Forskare vid Malmö universitet har tagit fram en modell för
https://www.vetenskaphalsa.se/3d-odlade-celler-ger-battre-bild-av-verkligheten/ - 2026-07-16
Identification of prostate gold fiducial markers in magnetic resonance imaging (MRI) images is challenging when CT images are not available, due to misclassifications from intra-prostatic calcifications. It is also a time consuming task and automated identification methods have been suggested as an improvement for both objectives. Multi-echo gradient echo (MEGRE) images have been utilized for manu
Partially unfolded alpha-lactalbumin forms the oleic acid complex HAMLET, with potent tumoricidal activity. Here we define a peptide-based molecular approach for targeting and killing tumor cells, and evidence of its clinical potential (ClinicalTrials.gov NCT03560479). A 39-residue alpha-helical peptide from alpha-lactalbumin is shown to gain lethality for tumor cells by forming oleic acid complex
20 september 2025 10:00 till 01:00 | Övrigt Naturvetenskapliga fakulteten bjuder på en vetenskapsfestival med massor av aktiviteter för både vuxna och barn. Du kan bland annat ta del av våra fartfyllda shower, populärvetenskapliga föredrag, planetarievisningar, experiment och utställningar, science slam och teleskoptitt. Välkommen till oss på Kulturnatten i Lund, lördagen den 20 september! View ac
https://www.lu.se/evenemang/naturvetarstraket-pa-kulturnatten-2025 - 2026-07-18
Blood pressure (BP) is a heritable determinant of risk for cardiovascular disease (CVD). To investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP) and pulse pressure (PP), we genotyped 50 000 single-nucleotide polymorphisms (SNPs) that capture variation in 2100 candidate genes for cardiovascular phenotypes in 61 619 individuals of European ancestr
The cationic dummy atom approach provides a powerful nonbonded description for a range of alkaline-earth and transition-metal centers, capturing both structural and electrostatic effects. In this work we refine existing literature parameters for octahedrally coordinated Mn(2+), Zn(2+), Mg(2+), and Ca(2+), as well as providing new parameters for Ni(2+), Co(2+), and Fe(2+). In all the cases, we are
New robotic applications often require physical interaction between the robot and its environment. To this purpose, external sensors might be needed, as well as a suitable way to specify the tasks. One complication that might cause problems in the task execution is orientation representation singularities. In this paper quaternions are used as a singularity-free orientation representation within t
Popular Abstract in Swedish Oberoende av om det är i ett samhälle, datornätverk eller organen i en mänsklig kropp, så är behovet av kommunikation stort i en komplex miljö. Eftersom den komplicerade människokroppen är beroende av kommunikation för att reglera funktioner, skickas otaliga mängder signaler oavbrutet. För att signalerna skall vara meningsfulla så måste de kunna tas emot och behandlas. Intercellular communication is of crucial importance in regulating physiology and G-protein coupled receptors (GPCRs) have evolved as an important mechanism in this process. Of the approximately 800 human GPCRs, about 160 are still considered to be “orphan” receptors for which an endogenous ligand remains to be identified. Since an estimated 50% of all clinical drugs act on 30 known GPCRs, the rem
This thesis studies the pricing of overnight indexed swap (OIS) caps using a one-factor CIR++ short-rate model with piecewise constant volatility. The model combines a CIR process with a deterministic shift, allowing an exact fit to the initial zero-coupon term structure and thereby enabling the remaining CIR parameters to be calibrated to other market instruments. OIS caplets are priced using Lap
Glycosylation defects occur in several human diseases. In IgA nephropathy, IgA1 contains O-glycans that are galactose-deficient and consist mostly of core 1 alpha2,6 sialylated N-acetylgalactosamine, a configuration suspected to prevent beta1,3 galactosylation. We confirmed the same aberrancy in IgA1 secreted by the human DAKIKI B cell line. Biochemical assays indicated CMP-NeuAc:GalNAc-IgA1 alpha
We present a new design method for robust low-delay coding of autoregressive (AR) sources for transmission across erasure channels. It is a fundamental rethinking of existing concepts. It considers the encoder a mechanism that produces signal measurements from which the decoder estimates the original signal. The method is based on linear predictive coding and Kalman estimation at the decoder. We e
Using an atomic model with a simplified-sequence-based potential, the folding properties of several different peptides are studied. Both alpha-helical (Trp cage, F-s) and beta-sheet(GB1p, GB1m2, GB1m3, Betanova, LLM) peptides are considered. The model is able to fold these different peptides for one and the same choice of;parameters, and the melting behaviour of the peptides (folded population aga
