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B cell superantigens (SAgs) have been implicated in human diseases by demonstrating non-clonotypic expansion of B cells bearing certain immunoglobulin variable region genes. One possibility is that, during infection with microorganisms secreting SAgs, these potent molecules might modulate BcR expression. To test this hypothesis, we investigated the potential effects of a SAg, protein L from Peptos
We have earlier shown that galectin-3, a lactose-binding mammalian lectin that is secreted from activated macrophages, basophils, and mast cells, induces activation of the NADPH oxidase in exudated but not in peripheral blood neutrophils (A. Karlsson, P. Follin, H. Leffler, and C. Dahlgren, Blood 91:3430-3438, 1998). The alteration in responsiveness occurring during extravasation correlated with m
BACKGROUND: From the viewpoint of the clinical neuropsychologist, it is not evident if the detection of solvent induced toxic encephalopathy (TE) could be optimized by a modification of the traditional test batteries, adding tests covering new dimensions or monitoring further functional domains. METHODS: To clarify this issue, TE patients were re-examined with (a) the tests traditionally used in s
Using the choroid plexus from pig a method has been developed to purify the epithelial cells from the underlying vascularized connective tissue stroma. An epithelial cell fraction was obtained that showed a purity of at least 95%, as determined by light microscopic analysis. The epithelial cells were investigated for the presence of binding sites for the neurotransmitter peptide, vasoactive intest
We establish the local well-posedness for a new nonlinearly dispersive wave equation which has solutions that exist for indefinite times as well as solutions that blowup in finite time. We also derive an explosion criterion for the equation, and we give a sharp estimate of the existence time for solutions with smooth initial data.
A combination of intumescent components was evaluated as a novel flame retardant system in a flexible polyurethane foam, and the incorporation of these components gave rise to a significant enhancement of the flame retardant properties of the foam. The heat release rate was lowered at an early stage as well as throughout the fire, the total heat production was decreased and the time to ignition wa
Recent evidence suggests that the breast and ovarian cancer susceptibility gene product BRCA1 is involved in at least two fundamental cellular processes: transcriptional regulation and DNA repair. However, the mechanism of action of BRCA1 in either of these processes is still unknown. Here, we report the characterization of a disease-predisposing allele of BRCA1, identified in a family with severa
Impinging flame jets are widely used in applications where high heat-transfer rates are needed, for instance in the glass industry. During the heating process of glass products, internal thermal stresses develop in the material due to temperature gradients. In order to avoid excessive thermal gradients as well as overheating of the hot spots, it is important to know and control the temperature dist
This document gives an overview of a Grid testbed architecture proposal for the NorduGrid project [1]. The aim of the project is to establish an inter-Nordic(1) testbed facility for implementation of wide a,rea computing and data handling. The architecture is supposed to define a Grid system suitable for solving data intensive problems at the Large Hadron Collider at CERN [2]. We present the vario
An in-house-made alignment system for deep X-ray lithography is presented that features low costs, low weight and little demand in space. Synchrotron radiation illuminates alignment marks on mask and substrate. The radiation transmitted through these alignment marks is detected by X-ray-sensitive diodes. The mask is fixed to the vacuum chamber, whereas the substrate is mounted on a six-axis kinema
Microdialysis was used for sampling enzyme hydrolysis products of starch hydrolysed with beta -amylase, pullulanase, and/or isoamylase, to obtain information about the molecular structure of starch. Starches from waxy, normal, and high amylose maize, and from normal and genetically modified potato (amylose deficient) were used, and also commercial potato amyloses. The hydrolysis products were anal
The lymphatic system, composed of lymphatic vessels, lymph, lymph nodes, and lymphocytes, is a distinctive vasculature (discontinuous basement membrane, open endothelial junctions, anchoring filaments, valves, and intrinsic contractility), different yet similar to the blood vasculature; an integral component of the plasma-tissue fluid-lymph circulation (the "blood-lymph loop"); and the center of t
We present a novel method for tracking multiple objects in video captured by a non-stationary camera. For low quality video, RANSAC estimation fails when the number of good matches shrinks below the minimum required to estimate the motion model. This paper extends RANSAC in the following ways: (a) Allowing multiple models of different complexity to be chosen at random; (b) Introducing a conditiona
This paper addresses the inverse problem of reconstructing a medium’s instantaneous, nonlinear response to electromagnetic excitation. Using reflection and transmission data for an almost arbitrary incident field on a homogeneous slab, we are able to obtain the nonlinear constitutive relations for both electric and magnetic fields, with virtually no assumptions made on the specific form of the rel
The CCSD(T) method has been used to compute a highly accurate quartic force field and fundamental frequencies for all 16O and 18O isotopomers of the ozonide anion. The CCSD and CASPT2 methods have also been used to verify the reliability of the CCSD(T) fundamental frequencies. The computed fundamental frequencies are in agreement with gas-phase experiments, but disagree with matrix isolation exper
In theory, the interaction between the worlds of environmental science and policy may seem straightforward. From a realm outside politics and power, scientists provide relevant knowledge about nature upon which informed policy decisions could be based. However, in reality this linear model tends to be replaced by a much more complex relationship where the distinction between facts and values, know
