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Objective: It has been suggested that elevated levels of C-reactive protein (CRP) might interfere with leptin signalling and contribute to leptin resistance. Our aim was to assess whether plasma levels of CRP influence leptin resistance in humans, and our hypothesis was that CRP levels would modify the cross-sectional relationships between leptin and measures of adiposity. Design and methods: We a
To control flight, flying insects extract information from the pattern of visual motion generated during flight, known as optic flow. To regulate their ground speed, insects such as honeybees and Drosophila hold the rate of optic flow in the axial direction (front-to-back) constant. A consequence of this strategy is that its performance varies with the minimum viewing angle (the deviation from the
Retinitis pigmentosa (RP) is an inherited disorder that results in vision impairment that specific therapeutic strategies are not available. However, it is widely regarded that the cGMP system, including cGMP and its interactor cGMP-dependent protein kinase (PKG), acts as a crucial effector during retinal degeneration. We have previously identified a list of cGMP-PKG-dependent genes in the context
Den här rapporten handlar om lärande från experiment och vänder sig till dig som arbetar med innovation i svenska regioner och kommuner. I fokus ligger frågor kring organisatoriskt lärande, som här förstås som ett medel för att uppnå strategisk förnyelse av en organisation. Lärande är således nära besläktat med förändring. Vår utgångspunkt är att allt lärande kan förstås som en form av översättnin
The development of immersive visuoauditory media brings to the fore several design challenges concerning cognitive human factors, such as visual perception, embodied interaction, and emotional engagement. With a focus on visual perception, our research emphasises a systematic study of embodied multimodal interaction in immersive settings and provides a cognitive model of visuospatial complexity th
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the benefits and harms of multisensory stimulation compared to any single sensory intervention or standard care for physical and neurological development in preterm infants.
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To evaluate the benefits and harms of olfactory stimulation with different odorants in the NICU for promoting development and preventing morbidity in preterm infants.
Human–robot collaboration (HRC) in manufacturing environments requires that physical safety can be guaranteed. Control methods that implicitly regulate the interaction forces between a controlled robot and its environment, such as impedance control, are often used for safety in HRC. However, these methods could be complemented by restricting the robot operational space for additional safety guaran
Advances in Earth observation capabilities mean that there is now a multitude of spatially resolved data sets available that can support the quantification of water and carbon pools and fluxes at the land surface. However, such quantification ideally requires efficient synergistic exploitation of those data, which in turn requires carbon and water land-surface models with the capability to simulta
Software process analysis and improvement relies heavily on empirical research. Empirical research requires measurement, experimentation, and modeling. Moreover, whatever evidence is gained via empirical research is strongly context dependent. Thus, it is hard to combine results and capitalize upon them in order to improve software development processes in evolving development environments. The pr
Subtle population structure remains a significant concern in genome-wide association studies. Using human height as an example, we show how quantile regression, a natural extension of linear regression, can better correct for subtle population structure due to its inherent ability to adjust for quantile-specific effects of covariates such as principal components. We utilize data from the UK Bioban
Genetic variation resulting from changes during somatic development in modular organisms may be inherited by subsequent generations due to the late development of their germ line. As a consequence, both sexually and asexually produced offspring may be genetically variable. The presence of heritable intraclonal variation and the great life history variation among modular organisms requires that evo
The reliability of diode lasers used in spectroscopic applications is limited by their intrinsic multimode and mode-jump behavior when wavelength-tuned by current or temperature. We report on a scheme for gas analysis based on temporal correlation between absorption signals from an unknown external and a known reference gas concentration, simultaneously recorded when the diode laser wavelength is
By using bootstrap technique we investigate the properties of the Breusch [Breusch, T.S., 1978. Testing for autocorrelation in dynamic linear models. Australian Economic Papers 17, 334-355]-Godfrey [Godfrey, L.G., 1978. Testing for higher order serial correlation in regression equations when the regressors include lagged dependent variables. Econometrica 46, 1303-1310] autocorrelation tests in dyn
Fuel cells are promising due to advantages with higher energy conversion efficiency and lower emissions of SOX, NOX and CO2 than conventional power systems. Solid oxide fuel cell (SOFC) is a high temperature fuel cell, which operates at 600-1000 ºC. The high operating temperature and the anode material allow SOFCs to operate with different types of fuels from both fossil and renewable sources due
Statement of Interest Assessment of visual field damage is the major index of the functional impact of glaucoma with direct relevance to quality of life measures. Visual field change was used as a primary endpoint for progression in the recent glaucoma trials and its measurement is the cornerstone of glaucoma management influencing therapeutic decisions. The objective of this perspective is to pro
Amendments to Articles 3.3 and 3.4 of the Kyoto Protocol have meant that detection of vegetation change may now form an interracial part of national soil carbon stocks. In this study multispectral multi-platform satellite data was processed to detect change to the surface vegetation of four peatland sites and one heath in Ireland. Spectral and spatial thresholds were used on difference images betw
