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OBJECTIVE: To evaluate the diagnostic potential of cerebrospinal fluid (CSF) levels of tau and beta-amyloid protein ending at amino acid 42 (Abeta42) as biomarkers for Alzheimer disease (AD) in clinical practice. DESIGN: A 1-year prospective study. SETTING: Community population-based sample of all consecutive patients admitted for investigation of cognitive symptoms to the Pitea River Valley Hospi
Arsenic enrichment of groundwater in the Red River (Song Hong) delta in Vietnam was discovered in 1998. Several studies performed in this area found concentrations of As exceeding the WHO-guideline of 10 lg/L. This study focuses on an area south of Hanoi city, Nam Du, where a new well field came into operation in 2004. The new well field is situated on the bank along the Red River in order to faci
Background: Identifying children with childhood-onset neurodevelopmental problems (NDPs, defined here as autism spectrum disorders [ASDs], attention-deficit/hyperactivity disorder [AD/HD], tic disorders [TDs], learning disorders [LDs] and development coordination disorder), using easily administered screening instruments, is a prerequisite for epidemiological research. Such instruments are also cl
Lipoprotein-associated phospholipase A2 (Lp-PLA2) is today considered a novel specific vascular inflammatory biomarker. The general aim of this thesis was to study the role and impact of Lp-PLA2 as cardiovascular (CV) risk marker in an epidemiologic perspective. Specific aims were to explore the cross-sectional association of Lp-PLA2 with traditional CV risk factors, to asses the genetic influence
Large-scale and population-wide monitoring of waders on their boreal and arctic breeding grounds has hitherto been lacking, mainly because logistics are truly challenging in regions with few ornithologists, vast areas and few roads. In Norway, Sweden and Finland (here 'Fennoscandia') there are now national monitoring schemes in place, aimed at tracking all bird species, which allows trends to be e
Critics maintain that there are a number of troublesome issues resulting from the construction sector’s way of operating and that these remain, despite widespread criticism and measures designed to change all of this. The construction sector’s and the critics’ manner of describing these problems fails to a large extent to take into consideration the way people function in connection with practical
The Siljan impact structure is the largest known impact structure in Europe, the result of a Late Devonian meteorite impact (380.9 +/- 4.6 Ma). It is outlined mainly by a ring of lakes and Palaeozoic sedimentary rocks of Ordovician to Devonian age. The Palaeozoic successions are generally poorly exposed, but often well preserved with clear stratigraphy. At some locations they are strongly tectonis
A two-dimensional numerical model of nearshore waves, currents, and sediment transport was developed. The multi-directional random wave transformation model formulated by Mase [Mase, H., 2001. Multidirectional random wave transformation model based on energy balance equation. Coastal Engineering Jounnal 43(4), 317-337.] based on an energy balance equation was employed with an improved description
Background: Evidence for an association of alcohol consumption with prognosis after a diagnosis of breast cancer has been inconsistent. We have reviewed and summarized the published evidence and evaluated the association using individual patient data from multiple case cohorts. Methods: A MEDLINE search to identify studies published up to January 2013 was performed. We combined published estimates
Purpose The XPC gene is involved in DNA damage recognition in the nucleotide excision repair pathway (NER) We investigated the additive effects of single nucleotide polymorphisms (SNPs) in bladder-cancer patients and population controls for three XPC polymorphisms A499V (C>T) K939Q (A>C) and poly AT (PAT -/+) Experimental Design 311 bladder-cancer patients from a population-based cohort and 337 po
Study I: Thirteen patients underwent a modified Ross operation in which the free-standing pulmonary autograft was supported externally by a Dacron vascular prosthetic jacket (DVPJ). The tailor-made DVPJ prevented dilatation of the neo-aortic root significantly following a median follow-up of 47 months compared to a cohort of l3 matched patients undergoing conventional Ross operation. Study II: A
I denna rapport diskuteras mjukvara som används för system bestående av automatiska maskiner som producerar produkter i ett företag. Testning är nödvändigt för att maskinerna ska fungera som planerat. Oftast görs testning manuellt, både under utveckling och medan produktionen är igång. Detta kallas för traditionell testning. Testning görs för att förbättra maskinens programkod. För att testen ska The topic of this thesis is software in systems of automated machines that produce products in a company. Testing of these systems is crucial for the machines to work as intended. Usually testing is done manually, both while the system is developed and while the production is running. This is called traditional testing. Testing is done to improve the machines program code. The machine needs to do
Trap roads are a part of the Swedish railway facility and resembles the safest front- and side protection at speed above 160 km/h. When designing Trap roads, some regulations needs to be followed. As these, in some cases, may be contradictory towards each other, the planners become somewhat insecure. The purpose of the master thesis has thenceforth been to clarify for the planners, as well as to w
Requirements from consumers and governments to produce more sustainable products have increased during recent years. Even if products are certified, one cannot make sure companies meet these requirements, since no chain of events can verify this exists. The transportation industry lacks certification and information on whether a product is transported in a sustainable way. The food industry, on th
Skatteflyktsproblematiken visar sig i samtliga samhällsgrupper och på alla inkomstnivåer. I syfte att förhindra skatteflykt tillämpas bland annat en lagstiftad generalklausul, vilken återfinns i 2 § lag (1995:575) mot skatteflykt. Problematiken tar dock inte slut där. Skatteflyktslagen har kommit att bli omdebatterad och ifrågasatt, främst med utgångspunkt i oklarheter avseende dess tolkning och tThe problems revolving tax evasion can be seen in all social groups and on all levels of income. In order to prevent tax evasion, a general clause has been legislated in the second paragraph of the Tax Evasion Act (1995:575). However, the problems do not end there. The Tax Evasion Act has been heavily debated as well as criticised, mainly based on ambiguity relating to the interpretation and appli
The purpose of this thesis is to cast light on the residential area Rosengård in Malmö which during the years between 1965 to 1975 was part of a programme known as "Miljonprogrammet", a project which was supposed to put an end to the housing shortages. The purpose of this thesis is also to investigate the social consequences in Rosengård, which arose as a result of Miljonprogrammet. Rose
The project was performed for FAS Converting Machinery AB (FAS) in Ystad with supervision from Industriell Elektroteknik och Automation at LTH. FAS is a company that makes machines for producing plastic bags on a roll. The problem given was to develop a sensor for detecting the perforations in the bags to ensure that the correct amount of bags was rolled up and that the tearing was in the right pl
Summary The station has always played an important role in development. In Sweden, railway building started in the middle of the 1900th century. The government financed the main rail lines, while private railway companies financed the small lines. The expansion of the railway lines was lead and planned by militaries, therefore the stations generally were drawn by trained militaries. Several statio
Kosovo was administered by the UN for almost ten years before unilaterally declaring its independence on the 17th of February 2008. In order to gain support from some major international political players, the declaration of independence was made in line with a number of requirements, including continued external presences, resulting in a ''supervised independence''. These requirem
Varumärkesrätten är territoriell, till skillnad från Internet, en av våra idag viktigaste marknadsplatser, som är globalt. Ett resultat av varumärkesrättens territorialitet och det faktum att rättigheterna till ett varumärke följer registrerings- eller inarbetningslandets gränser är att det är möjligt för ett varumärke att ägas av olika innehavare i olika länder. Vilket kan leda till problem när sTrademark law is territorial, contrary to one of today’s most important market places - the Internet, which is a global medium. Since the exclusive right to a trademark follows the boundaries of its country of registration or incorporation, it is possible for the same trademarks to be registered by different owners in different countries, something that can lead to problems on the Internet. The bo
