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Surgical Extent and Long-term Survival in Appendiceal Adenocarcinoma : A Systematic Review and Meta-analysis

BACKGROUND/AIM: Appendiceal adenocarcinomas are rare tumours with aggressive traits, most often diagnosed incidentally after routine appendectomy. Survival rates vary greatly between the different subgroups, and adenocarcinoma has the worst prognosis. Surgery is the only curative treatment, however, the long-term benefit of extended surgical resections over appendectomy has not been established. T

Post-screening risk of tuberculosis progression : a three-year retrospective cohort study of asylum seekers in Sweden

Introduction: Strategies for tuberculosis (TB) elimination in low-incidence countries involve screening recent migrants from TB-endemic regions for TB infection (TBI) and providing TB preventive treatment (TPT) to individuals with an increased risk of reactivation. This study aimed to determine TB incidence and identify reactivation risk markers in a cohort of asylum seekers in Sweden after screen

Echocardiographic grading of right ventricular dysfunction improves risk stratification of patients with severe heart failure

Background: Right ventricular dysfunction (RVD) is a marker of adverse outcomes in heart failure (HF). We used a 5-point RVD score to describe three phenotypes (preserved RV function, RVD and RV failure) and investigated their relationhip with cardiac function and their contribution to risk stratification. Methods: Patients (n = 201) with HF, undergoing right heart catheterization and echocardiogr

Increased intracranial pressure in severe traumatic axonal injury patients - A retrospective single-center study

Introduction: Traumatic axonal injury (TAI), often caused by rapid rotational forces and high-energy accidents, is common in severe traumatic brain injury (sTBI). The intracranial pressure (ICP) dynamics are often unpredictable, and the need for ICP monitoring remains debated. Research question: What is the incidence of ICP elevation in patients with TAI, and how often is escalated ICP-lowering tr

Potential Policies and Laws to Prohibit Weight Discrimination : Public Views from 4 Countries

CONTEXT: People viewed as "overweight" or "obese" are vulnerable to weight-based discrimination, creating inequities and adverse health outcomes. Given the high rates of obesity recorded globally, studies documenting weight discrimination in multiple countries, and an absence of legislation to address this form of discrimination, research examining policy remedies across different countries is nee

Tumor-Infiltrating Immune Cells Are More Abundant in Lung Metastases From Colorectal Cancer Than in Paired Primary Tumors and Their Prognostic Value Depends on Adjuvant Chemotherapy

INTRODUCTION: The immune microenvironment plays a crucial role in the progression of colorectal cancer (CRC), but its variation across primary tumors and metastatic sites remains incompletely understood. In this study, we compared the composition and prognostic significance of the immune microenvironment in lung metastases, paired primary tumors, and liver metastases from a retrospective cohort of

Genetic Susceptibility to Diabetes Subtypes and Risk of Developing Coronary Artery Disease

OBJECTIVE: Diabetes significantly increases the risk for atherosclerotic complications, including coronary artery disease (CAD). Previous studies have suggested that adult-onset diabetes can be classified into five different clinical subtypes, including moderate obesity-related diabetes (MOD). The aim of this study was to investigate the genetic associations between the five diabetes subtypes and

Clinical Outcomes in Percutaneous Coronary Intervention: Studies on Chronic Coronary Syndrome and Drug-Coated Balloons

Background: Percutaneous coronary intervention (PCI) is frequently used in the treatment of chronic coronary syndrome (CCS), although its impact on long-term prognosis and symptom relief remains debated. Among patients undergoing revascularisation with PCI, data on clinical outcomes following drug-coated balloon (DCB) based PCI in unselected patient populations is limited, and the comparative effe

Hydrolysis och chylomicron arachidonate and linoleate ester bonds by lipoprotein lipase and heaptic lipase

Chylomicrons labeled with [3H]arachidonic and [14C]linoleic acid were incubated with bovine milk lipoprotein lipase or rat postheparin plasma, containing both lipoprotein lipase and hepatic lipase. During incubation with bovine lipoprotein lipase, [3H]arachidonic acid was released from chylomicron triacylglycerols at a slower rate than [14C]linoleic acid. Only small amounts of [14C]linoleic acid w

Det interaktiva teaterrummet + Ungdomars politiska engagemang = Sant? - En studie om deltagarteaterns utbildande effekter

Several of researches shows that youths seek other kinds of participatory channels for political engagements then the representative structure can give them. Citizens who participate in the political process develop an increased knowledge about the society and the more knowledge about the society the larger reason to participate. This thesis was done with the assumption that the experience of part

Musikens tyngdpunkter - om interaktionen mellan meter och rytm och dess roll i den interpretativa processen

Title_ Metric points of gravity in music - interaction between meter and rhythm and its role in the process of musical interpretation. The aim of the present study is to shed more light on the following questions: What is the role of interaction between meter and rhythm in the process of musical interpretation? What motives lie behind the choices that music students make when interpreting a piece

Dynamic modelling of bathing water quality with biodegradation of Escherichia coli in TELEMAC-3D

När städerna växer, ökar risken för fekal kontaminering på våra badplatser. Kontamineringen är oftast kortvarig men utgör en hälsorisk för badarna. Hur kan vi lösa detta? Information kring badvattenkvalité är idag begränsad. Ändå påverkas vårt dagliga liv av kvalitén på vattnet i och med att våra badplatser ofta ligger nära stadsområden. De flesta badplatserna i Sverige idag visar god vattenkvaliBathing water is of great concern as almost all bodies of water in Sweden today are affected by human activities. Usage of models for bathing water quality may give the possibility to assess and evaluate short-term contamination. The main objective of this thesis was to develop and evaluate a script for degradation of the faecal indicator bacteria Escherichia coli, E. coli, in an aquatic environme

MiFID II vis a vis IDD, liknande reglering? - En analys om den överlappande regleringen i MiFID II & IDD.

År 2014 antogs direktiv 2014/65EU, även kallat MiFID II. Direktivet reglerar bland annat hur finansiella institut ska organisera sin verksamhet för att skydda kundernas intresse i de fall kunderna handlar med finansiella instrument. Direktivet är skrivet med ett starkt kundskydd och harmoniserad inre marknad som mål. Två år senare, 2016, antogs direktiv 2016/97, även kallat IDD. IDD är motsvarandeThe financial crisis 2008 revealed several weaknesses in the regulation on the financial markets. It was evident that a new, stricter, regulation was needed to be created. Directive 2014/65EU, MiFID II and directive 2016/97, IDD, is a part of the new financial regulation. MiFID II regulates how financial institutes can interact with investors, when investors seek to buy or sell financial instrumen

Business Model Innovation - Challenges and Opportunities in the Swedish Newspaper Industry

The digital era has mercilessly affected the media landscape by changing the way information and news are disseminated and consumed. This has led to an increased need to move activities online and an outdated business model among newspapers. The Swedish newspaper industry has so far struggled to do business in the digital world. Hence, the need for business model innovation is greater than ever. I

Green energy defaults: Too effective or not effective enough?

Green energy defaults (where the uptake of renewable energy is promoted among households by opt-out tariffs) are gaining increasing interest with policy makers, due to the high enrolment rates shown in (experimental) studies. Such default choices are often justified on normative and behavioural grounds as although consumers express a desire and willingness to pay for green energy, they often fail

Markvederlag vid fastighetsreglering - En studie om tillämpningen av FBL 5 kap. 2 §

Öga för öga, tand för tand är en straffrättslig princip som myntades av kung Hammurabi i Babylonien kring år 1700 före Kristus genom Hammurabis lag. Principen om öga för öga, tand för tand innebär att den som orsakat skada ska lida samma skada. Svensk straffrätt har gått från resonemanget att ”ont ska botas med ont” till straff och skadestånd i pengar och därför finns inte principen om öga för ögaChapter 5 article 2 of the Property Formation Act reads that the person who forfeitsland shall be compensated with land primarily. This means that the principal rule isthat land shall be compensated with land, but when this is not deemed appropriated compensation in money is acceptable. Furthermore, the paragraphmeans that the Surveying Authority (LM) may decide against the land owners wish that c

Gå i cirklar : litteratur, läsning och identitet i bokcirklar för gymnasieelever

This master thesis in library and information science is centered around two reading circles taking place at the libraries of Swedish upper secondary schools. The aim of the thesis is to study how the participants (ages 16-18) in the reading circles reflect on their own reading practices and their identities as readers. One main point of the thesis is that reading circles are forms of reading comm

King of the Road or Caught in the Headlights? - A Managerial Perspective on the Role and Execution of Peripheral Vision in the German Car Rental Industry

The failure or flourishing of companies in their core businesses can often be attributed to events and developments rooting outside their focus of attention. Many research streams are concerned with early detection, interpretation and acting upon these weak signals from companies’ peripheries - with Peripheral Vision by Schoemaker & Day (2006) being one of the most systematic approaches. Due t

To waste, or to resource? A comparative Life Cycle Assessment of recovering bottom ash from waste incineration for use in road construction in Malmö.

The low-carbon benefits and emissions savings from circular economy (CE) strategies are not yet well understood, yet are crucial for global development within Planetary Boundaries. Using the mineral fraction of waste incinerator bottom ash (MIBA) as construction material in road construction is one application of a CE strategy that could lead to environmental gains by substituting energy-intensive