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Genome structure has been found to be highly conserved between distantly related birds and recent data for a limited part of the genome suggest that this is true also for the gene order (synteny) within chromosomes. Here, we confirm that synteny is maintained for large chromosomal regions in chicken and a passerine bird, the great reed warbler Acrocephalus arundinaceus, with few rearrangements, bu

BACKGROUND: The amount of myocardium at risk (MaR) during acute coronary occlusion and the duration of occlusion are important determinants of final infarct size. The main goal of early reperfusion therapy is to salvage ischemic myocardium, thereby preserving left ventricular function. The aims of the present study were to test the feasibility of developing polar plot representations of MaR, for p

Cholecystokinin (CCK)-expressing basket cells encompass a subclass of inhibitory GABAergic interneurons that regulate memory-forming oscillatory network activity of the hippocampal formation in accordance to the emotional and motivational state of the animal, conveyed onto these cells by respective extrahippocampal afferents. Various excitatory and inhibitory afferent and efferent synapses of the

Gesture has been acknowledged as a pivotal part of delivery in political rhetoric for millennia. Typically, politicians are seen as adhering to a style of gesturing encouraging pragmatic gestures, namely those that operate on the level of discourse such as providing emphasis, while being discouraged from using representational gestures, namely those depicting the content of speech iconically, as t

Bakgrund: Naturen har potentiellt positiv effekt på mental hälsa, vilket kan användas inom rehabilitering. Forskning har bedrivits på ämnet inom psykologi, landskapsarkitektur och stadsplanering. Det finns studier som undersöker naturbaserade interventioners (NBI) effekter i rehabiliteringsträdgård, men inte av NBI förlagd i allmän miljö. Syfte: Syftet är att kartlägga innehåll, genomförande och eBackground: Nature's potentially positive effect on human health may be used for rehabilitation purposes. This is researched in the field of psychology, landscape planning and urban planning. There are studies of the effect of nature-based interventions (NBI) located in rehabilitation gardens, but not of NBI in public nature-environments. Aim: to survey the content, implementation and effects

This thesis explores the patterns of shared e-scooter usage in the cities of Oslo and Stockholm, with a focus on understanding how these trips relate to public transport services. While e-scooter usage has soared during the last decade, policy makers, urban and transportation planners attempt to understand this new phenomenon and its effect to public transport. Geographic Information Systems (GIS)

Prior research has established that misinformation can distort episodic memory, and that attention plays a critical role in how these distortions unfold. Eye movements, as a real-time index of attention, offer a powerful method for investigating the mechanisms linking misinformation and memory. Although earlier studies have examined misinformation effects on eye movements, these studies have mostl

Fler växtarter i fröblandingen leder inte till en högre mångfald av pollinatörer i blomremsor? Dagens högintensiva jordbruk och markanvändning har resulterat i stora förluster av flera olika pollinatörsgrupper. Mycket av deras naturliga livsmiljöer har försvunnit samtidigt som de utsätts för bekämpningsmedel som har ytterligare negativ påverkan. Detta är oroväckande då 90 % av alla vilda växtarteSowing wildflower strips is a commonly applied agri-environmental scheme in agricultural landscapes used to mitigate the ongoing decline in pollinator diversity and abundance. Flower strips can be implemented as either annual or perennial plantings to promote biodiversity and/or ecosystem services. As different objectives may require different seed mixtures, this may impact how various pollinator

Although many efforts have been made to eliminate barriers in public transport worldwide, research shows that public transport is still often perceived as challenging, inconvenient, and inaccessible for many people with disabilities. A growing body of research points to several issues, relating to the spatial and temporal distribution of public transport, affordability, safety, and social barriers

Precapillary pulmonary hypertension (PH) is characterized by increased pulmonary vascular resistance (PVR), with progressively altered right (RV) and left ventricular (LV) hemodynamics and function. Kinetic energy (KE) from 4D flow cardiovascular magnetic resonance (CMR) is a measure of intracardiac hemodynamics. In this observational case–control study, we investigate physiological mechanisms inf

IntroductionThe evidence for assessing whether a single stab injury to the trunk was inflicted by another person in an assault or self-inflicted has primarily been derived from autopsy studies. In this study, we investigate whether victim demographics, crime scene circumstances, and the injury characteristics of assault survivals are interchangeable with homicide characteristics, with a specific f

Integrated pest management (IPM) is an important tool for sustainable crop production. IPM includes a diversity of methods, e.g., the use of biological control agents (BCAs) for disease control or growth promotion. While there is an increasing interest in the use of BCAs, less is known about their environmental costs and benefits on wild species, such as wild crop relatives. For example, a BCA may

INTRODUCTION: Large language models (LLMs) have gained increasing popularity in several medical disciplines. In orthopedic research however, their integration into routine practice have been questioned as they do not seem to outperform experienced clinicians. Conversely, research on the role of artificial intelligence in hand surgery remains limited. This study aims to evaluate two common LLMs in

Background: Patients with diabetes admitted to emergency care face a higher risk of complications, including prolonged hospital stays, admissions to the intensive care unit and mortality. Aim: To develop a machine learning (ML) model to predict 30-day mortality in patients with diabetes admitted to the emergency department (ED). Design and setting: A cohort study utilizing data from all nine ED’s

Objectives Assessment of Different NEoplasias in the adneXa (ADNEX) and Risk of Malignancy Index (RMI) are models that estimate the risk of malignancy in ovarian masses based on clinical and ultrasound information. The aim is to perform a meta-analysis of studies that compared the performance of the two models in the same patients (‘head-to-head comparison’). Design Systematic review and meta-anal

Background: Neoadjuvant cisplatin-based combination chemotherapy (NAC) is standard perioperative treatment of patients with muscle-invasive urothelial bladder cancer (MIBC); however, about half of the patients experience recurrence of the disease. Biomarkers for response and survival represent an unmet medical need. We used tumor specimens from transurethral resections of the bladder to explore ge

Background: Preparing retrospective dose data for risk modeling using large study cohorts can be time consuming as it often requires patient-wise manual interventions. This is especially the case when considering organs at risk (OARs) not systematically delineated historically. Therefore, we aimed to develop and test a semi-automated workflow for cohort-wise preparation of radiotherapy data from t

Background and purpose: The study aims to evaluate dosimetric properties of hypofractionated treatment plans integrating focal boost, using registered whole-mount histopathology (WMHP) as reference standard. Methods: Fifteen men from the PAMP trial (EudraCT: 2015-005046-55) were included. Participants had ≥ 1 ISUP Grade group ≥ 4 lesion and underwent [68Ga]prostate-specific membrane antigen (PSMA)