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Precipitation suppression due to an increase of aerosol number concentration in stratiform cloud is well-known. It is not certain whether the suppression applies for deep convection. Recent studies have suggested increasing precipitation from deep convection with increasing aerosols under some, but not all, conditions. Increasing precipitation with increasing aerosols can result from strong intera
The human genome, in common with all mammalian genomes, carries a high load of inheritable retroviral sequences. We have identified and characterized a novel family of these endogenous retroviruses and have named this family HERV-F as based on the primer binding sites of three members. The HERV-Fs are C-type endogenous retroviruses that have unique gag, pol and env regions that are, based on phylo
Popular Abstract in Swedish Ateroskleros, ofta kallad åderförkalkning, är en sjukdom som påverkar stora och medelstora artärer såsom aorta, kranskärl, karotis och perifera artärer. Åderförkalkning i kranskärlen orsakar 70 % av dödsfallen hos dessa patienter och räknas som den främsta dödsorsaken i västvärlden. Cerebrovaskulär sjukdom orsakar 20 % av dödsfallen och är den tredje vanligaste dödsorsaAtherosclerosis is the leading cause of death and disability in the western world. Its clinical complications include acute myocardial infarction, sudden death and stroke. Thirty to 40 % of all ischemic strokes are caused by a carotid stenosis. The acute clinical event is triggered by an occluding thrombosis and even more frequently by embolization. Besides the degree of stenosis, the structure of
Popular Abstract in Swedish Livskvalitet, motivation och kostnader vid rehabilitering av patienter med långvariga muskuloskeletala besvär Långvariga muskuloskeletala besvär är ett omfattande medicinskt, socialt och ekonomiskt problem i utvecklade länder. Syftet med avhandlingen var att utvärdera ett multidisciplinärt rehabiliteringsprogram som fokuserade på Basal Kroppskännedom och kognitiv och Prolonged musculoskeletal disorders (PMSD) is an escalating medical, social and cost problem in developed countries. The complexity of PMSDs has emphasised the need of developing effective multidisciplinary rehabilitation programme with a holistic approach. The aim of the thesis was to evaluate the outcome of a multidisciplinary rehabilitation programme focusing on Body Awareness Therapy and cogn
Stroke is a major cause of disability worldwide and different types of impairments can affect the individual’s ability to manage everyday activities such as travel that is essential for participation in society. The purpose of this study was to investigate the feasibility of a new self-management intervention (BUS TRIPS) focusing on travelling by bus, and potential contributions to an improved abi
Background: Recent randomized trials demonstrated that laparoscopic lavage compared with resection for Hinchey III perforated diverticulitis was associated with similar mortality, less stoma formation but a higher rate of early reintervention. The aim of this study was to compare 1-year outcomes in patients who participated in the randomized Scandinavian Diverticulitis (SCANDIV) trial. Methods: Be
Microtubule-disturbing drugs inhibit lysosomal trafficking and induce lysosomal membrane permeabilization followed by cathepsin-dependent cell death. To identify specific trafficking-related proteins that control cell survival and lysosomal stability, we screened a molecular motor siRNA library in human MCF7 breast cancer cells. SiRNAs targeting four kinesins (KIF11/Eg5, KIF20A, KIF21A, KIF25), my
Life time occurrence of inguinal hernia is 30% of men. Most are symptomatic and will require surgical treatment. Operation will commonly cure the hernia but remaining chronic pain or new pain is seen in 10–15%. Groin pain due to an inguinal hernia can cause impairment of sexual functions. This is sparsely studied. The aim was to analyse postoperative long term chronic pain and sexual impairment in
According to the brood reduction hypothesis, parents adjust their brood size in response to current environmental conditions. When resources are abundant, parents can successfully raise all hatched offspring, but when resources are scarce, brood reduction, i.e., the sacrifice of some siblings to secure the quality of a subset of offspring, may maximize fitness. Differential transfer of maternal an
The 12-item Short-Form Health Survey (SF-12) is an abbreviated version of the SF-36, one of the most widely used patient-reported health outcome rating scales. Similar to the SF-36, it yields summary scores of physical and mental health (PCS and MCS, respectively). However, SF-36 derived PCS and MCS scores have not been found valid in neurological disorders such as Parkinson's disease (PD). Here w
Adsorption of trimethyl phosphate (TMP) and triethyl phosphate (TEP) on well-characterized nanopartides of hematite (alpha-Fe2O3), maghemite (gamma-Fe2O3), and goethite (alpha-FeOOH) has been studied by in situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS), 2D correlation DRIFTS analysis, and X-ray photoelectron spectroscopy (XPS) on dry and water pre-covered surfaces. It is
Importance: The increasing burden due to cancer and other noncommunicable diseases poses a threat to human development, which has resulted in global political commitments reflected in the Sustainable Development Goals as well as the World Health Organization (WHO) Global Action Plan on Non-Communicable Diseases. To determine if these commitments have resulted in improved cancer control, quantitati
The measurement of potential enzymatic activities has been proposed as an efficient method to infer nutrient limitations for microorganisms in environmental samples. To validate this use, confirmation with direct methods of microbial growth responses to resource additions are required. We experimentally manipulated nutrient-poor soils from the afromontane subtropics with relatively low (grassland
BACKGROUND: The proteasome system plays an important role in synaptic plasticity. Induction and maintenance of long term potentiation is directly dependent on selective targeting of proteins for proteasomal degradation. The 20S proteasome activator PA28αβ activates hydrolysis of small nonubiquitinated peptides and possesses protective functions upon oxidative stress and proteinopathy. The effect o
Objective: The 4.2-day half-life I-124 favors its use for positron emission tomography (PET) of monoclonal antibodies (mAbs). However, high positron energy and beta(+)-associated cascade gamma rays pose image resolution and background noise problems for I-124. This study evaluated quantitative PET of an I-124 mAb in tumor-bearing mice. Methods: An R4 microPET (TM) (Siemens/CTIMI, Knoxville, TN) wa
The city of Helsingborg wishes to see an increase in bicycle traffic. One of the measures that have been taken to achieve this is to build elevated bicycle crossings at intersections between bicycle paths and carriageways. This thesis deals with the particular kind of elevated bicycle crossing that is situated at the intersection between a main street with a bicycle path alongside it and a side st
I januari 2009 fick en student vid ett vuxengymnasium i Tensta besked om att hon inte tilläts bära niqab i skolan. Niqaben, som är en heltäckande slöja där endast ögonen är synliga, medförde enligt skolan pedagogiska svårigheter såväl som säkerhetsrisker. Händelsen anmäldes till Diskrimineringsombudsmannen och studenten tilläts gå kvar på skolan i väntan på myndighetens beslut. Frågan om dylika heIn January of 2009 a student at an upper secondary school for adults in Tensta was informed that she was not allowed to wear a niqab to school. According to the school board, the niqab, which is a full veil that leaves only the eyes fully visible, implied both security risks as well as pedagogical difficulties. The incident was reported to the Equality Ombudsman, and awaiting the Ombudsman’s decis
The strain on water resources with the increased man-induced environmental changes through water pollution, is creating a growing demand in the understanding and management of complex hydrological systems where both water quality and quantity are concerned. This is beyond the capabilities of lumped models and more advanced tools are needed to predict these effects and hence the need for physically
Background: Managed Ventricular Pacing (MVP) and Search AV+ (SAV+) are two pacing algorithms designed to reduce ventricular pacing, MVP promotes conduction by operating in AAI/R mode with backup ventricular pacing during atrioventricular block (AVB). SAV+ operates in DDD/R mode with a nominal AV extension of 290 ms during atrial sensing and 320 ms during atrial pacing. The reduction in ventricular
Background: The recommendations and the updated EAU guidelines consider early detection of PCa with the purpose of reducing PCa-related mortality and the development of advanced or metastatic disease. Objective: This paper presents the recommendations of the European Association of Urology (EAU) for early detection of prostate cancer (PCa) in men without evidence of PCa-related symptoms. Evidence
