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Gaia Data Release 2 : The astrometric solution

Context. Gaia Data Release 2 (Gaia DR2) contains results for 1693 million sources in the magnitude range 3 to 21 based on observations collected by the European Space Agency Gaia satellite during the first 22 months of its operational phase. Aims. We describe the input data, models, and processing used for the astrometric content of Gaia DR2, and the validation of these resultsperformed within the

Increased expression of CD200 on circulating CD11b+ monocytes in patients with neovascular age-related macular degeneration

OBJECTIVE: Dysregulation of retinal microglial activity has been implicated in the pathogenesis of neovascular age-related macular degeneration. Microglia activity can be regulated through the membrane protein CD200 and its corresponding receptor, the CD200 receptor (CD200R). Because both the ligand and the receptor are expressed on a broad spectrum of cell types, we set out to study the expressio

Glucose-dependent insulinotropic peptide and risk of cardiovascular events and mortality : a prospective study

AIMS/HYPOTHESIS: Evidence that glucose-dependent insulinotropic peptide (GIP) and/or the GIP receptor (GIPR) are involved in cardiovascular biology is emerging. We hypothesised that GIP has untoward effects on cardiovascular biology, in contrast to glucagon-like peptide 1 (GLP-1), and therefore investigated the effects of GIP and GLP-1 concentrations on cardiovascular disease (CVD) and mortality r

Searching for monocular microsaccades - a red Hering of modern eye trackers?

Despite early reports and the contemporary consensus on microsaccades as purely binocular phenomena, recent work has proposed not only the existence of monocular microsaccades, but also that they serve functional purposes. We take a critical look at the detection of monocular microsaccades from a signal perspective, using raw data and a state-of-the-art, video-based eye tracker. In agreement with

Human fetal basal forebrain neurons grafted to the denervated rat hippocampus produce an organotypic cholinergic reinnervation pattern

The septal/diagonal band (SDB) area, obtained from a 9- to 10-week-old aborted human fetus, was grafted to the hippocampal formation of adult, immunosuppressed rats subjected to an aspirative lesion of the fimbria-fornix. Nineteen weeks after transplantation, microscopical analysis revealed large, partly acetylcholinesterase (AChE)-positive grafts in the hippocampus in 3 of the 5 recipients. The A

Reduction of vanadium(V) with Acidithiobacillus ferrooxidans and Acidithiobacillus thiooxidans

Biotechnological leaching has been proposed as a suitable method for extraction of vanadium from spent catalysts and oil ash. In the biological leaching process, the vanadium(V) can be reduced to vanadium(IV), which is a less toxic and more soluble form of the vanadium. The present investigation showed that Acidithiobacillus ferrooxidans efficiently reduced vanadium(V) in the form of vanadium pent

The role of lipid rafts in LPS-induced signaling in a macrophage cell line.

The significance of lipid rafts in lipopolysaccharide (LPS) signaling in macrophages was studied through isolation of them by gradient centrifugation and subsequent visualization of signal molecules using antibodies. LPS signaling is initiated by binding to Toll-like receptor-4 (TLR4) and the co-receptor CD-14, leading to activation of downstream targets, such as MAP kinases. In this study, we sho

Large spectral diffusion of conjugated polymer single molecule fluorescence at low temperature

The conductive polymer poly(2-methoxy-5-(2'-ethylhexyloxy)-1,4- phenylene vinylene) (MEH-PPV) was investigated by means of single molecule spectroscopy at 15 K. MEH-PPV single chains were deposited onto a surface from a toluene solution and covered with a polymer cap layer spin-coated from an aqueous solution for protection from air. The MEH-PPV molecules exhibited large fluorescence spectral diff

The relationship between synovial fluid biomarkers of articular cartilage metabolism and the patient's perspective of outcome depends on the severity of articular cartilage damage following ACL trauma.

Anterior cruciate ligament (ACL) trauma often occurs in combination with injury to the articular cartilage of the knee, this can result in earlier radiographic evidence of post traumatic osteoarthritis (OA) of the knee compared to the contralateral, ACL intact knee; however, the biomechanical and biological mechanisms associated with the onset and progression of this disease are not understood. We

Health-related quality of life in persons with Parkinson's disease. Aspects of symptoms, caregiving and sense of coherence.

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Parkinson's sjukdom är näst efter Alzheimer's sjukdom den vanligast förekommande neurologiska sjukdomen. Parkinson's är en förhållandevi's vanlig neurologisk sjukdom och det finn's belägg för den i alla kulturer där sjukdomsstatistik för's. I Sverige lever idag cirka 20 000 personer med sjukdomen. Förekomsten av sjukdomen är starkt åAbstract Aims: The aim of this thesis was to investigate how the impact of Parkinson’s disease, a chronic neurodegenerative disorder, influences the person’s health-related quality of life. The aim was also to investigate nursing assessment and management of Parkinson’s in elderly persons. Methods: The study started in1998, one year later a follow-up was conducted. The sample contained in the fir

Genetic Engineering of Industrial Micro-organisms - Casein hydrolysis by the lactic acid bacteria Lactococcus lactis subsp. cremoris and Lactobacillus rhamnosus and Xylose fermentation by the yeast Saccharomyces cerevisiae

Micro-organisms are used industrially by humans, to improve production, either qualitatively or quantitatively, and to enhance profit or value. In cheese production, the starter bacteria hydrolyse casein degradation products generated by rennet. Some bitter peptides accumulate during cheese ripening, and their degradation would improve the flavour of the cheese. Plasmid pHP003 from the starter st

Globalisation, class and cultural identity at the end of hegemony

Globalisation traps, balkanisation, class polarisation, the dominance of transnational companies and the subordination of transnational migrants are all part of the imaging broadcast over the global media, and they merge with experiences of fear and joy in the countdown to the next millennium. The globalisation of fragmentation consists in driving a class wedge through the ethnic groups themselves

Birth outcomes in a Swedish population of women reporting a history of violence including domestic violence during pregnancy : A longitudinal cohort study

Background: Victimisation of women is encountered in all countries across the world, it damages the mental and physical health of women. During pregnancy and the postpartum period, women are at a greater risk of experiencing violence from an intimate partner. The aim of this study was to explore childbirth outcomes in a Swedish population of women reporting a history of violence including domestic

Minnet går gränsvakt. Fyra poeter ur 1970-talets grekiska diktargeneration

Popular Abstract in Swedish Syftet med min avhandling har varit att visa på några viktiga drag som framträder vid en undersökning och en jämförelse av fyra etablerade poeter från 1970-talets diktargeneration i Grekland: Michalis Ganas, Maria Kirtzaki, Tzeni Mastoraki och Kostas Papageorgiou. Genom att deras litterära skapande satts i en tydlig relief mot relevanta politiska, historiska och samhäll