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This paper presents the results of a production experiment on the syntax–prosody mapping in Tokyo Japanese, whereby the phonetic realization of syntactic phrase and clause boundaries were systematically compared. The data consist of 672 utterances of read speech from fourteen subjects. The results corroborate earlier findings on the mapping of syntactic phrases to phonological phrases, but do not

The agile methodology is gaining attention among practitioners and researchers in hardware development. As a new methodology, it is a source of misunderstandings and misinterpretations. This is problematic at the managers' levels as they may hinder its adoption or lead to its impractical implementation and use. This study, therefore, aims to explore the manager's level of understanding of the agil

In this paper we seek to reflect on the way in which 'digital cities' later re-emerge as 'smart cities' (both in terms of the approaches and also the actual cities) and what lessons can be learned about the role of ICTs in how they shape urban space. We will focus on looking at how the lack of understanding of the city as a 'place' is often a common factor in the lack of longevity in 'digital city

Individuals are expected to avoid mating with relatives as inbreeding can reduce offspring fitness, a phenomenon known as inbreeding depression. This has led to the widespread assumption that selection will favour individuals that avoid mating with relatives. However, the strength of inbreeding avoidance is variable across species and there are numerous cases where related mates are not avoided. H

Autoantigen discovery is a critical challenge for the understanding and diagnosis of autoimmune diseases. While autoantibody markers in current clinical use have been identified through studies focused on individual disorders, we postulated that a reverse approach starting with a putative autoantigen to explore multiple disorders might hold promise. We here targeted the epidermal protein transglut

LukGH (LukAB) is a potent leukocidin of Staphylococcus aureus that lyses human phagocytic cells and is thought to contribute to immune evasion. Unlike the other bi-component leukocidins of S. aureus, LukGH forms a heterodimer before binding to its receptor, CD11b expressed on professional phagocytic cells, and displays significant sequence variation. We employed a high diversity human IgG1 library

Edinburgh was an Enlightenment city of regional, national and global influence. But how did the people of Enlightenment Edinburgh understand and order their world? How did they encounter, compare and produce different kinds of spaces, from the urban to the world scale? And how did this city set the universal standards by which other places should be judged and transformed?The Geographies of Enligh

Emotion regulation has been specifically linked to both non-suicidal self-injury (NSSI) and attempted suicide. It is also known that self-harm is disproportionally higher (30–68.4%) in forensic samples than in the general population, yet knowledge about the association between emotion regulation and self-harm in forensic settings is scarce. The purpose of this study was to describe emotion regulat

Background: Harmful glucose exposure and absorption remain major limitations of peritoneal dialysis. We previously showed that inhibition of sodium glucose cotransporter 2 did not affect glucose transport during peritoneal dialysis in rats. However, more recently we found that phlorizin, a dual blocker of sodium glucose co-transporter 1 and 2, reduces glucose diffusion in peritoneal dialysis. Ther

Understanding the causes and limits of population divergence in phenotypic traits is a fundamental aim of evolutionary biology, with the potential to yield predictions of adaptation to environmental change. Reciprocal transplant experiments and the evaluation of optimality models suggest that local adaptation is common but not universal, and some studies suggest that trait divergence is highly con

This paper presents and discusses a recently digitized, dataset of strikes and lockouts in Sweden for the period 1859-1902. The dataset, which originally was collected by Axel Raphael by retrospectively browsing through newspapers, pre-dates the Swedish official statistics on work stoppages that began in 1903. Whereas Raphael’s data have been used to illustrate the long-run development of strikes,

Informal leaders in the choral voice.Choir leaders’ experience of collaboration between the choristers.Most choirs and choir leaders have the aim to make the individual voices soundas unison as possible in the different choral voices, according to both timing,synchronisation and vocal blend.The aim of the present study was to investigate experienced choir leaders’experience and understanding of po

Intergrowths of hexagonal and cubic phases of faujasitic structure have been synthesised using crown ether templates and the phase integrity monitored by high-resolution electron microscopy.

A novel approach is developed for predicting body trajectories for cancer progression, where conditional probabilities of clinical data are modeled using Hidden Markov Model techniques. Basically, each potential body site is encoded by an N-letter code, and a disease trajectory is described in terms of a string of letters. Patient data base records are then represented by such strings with differe

Paenibacillus larvae, causative agent of American Foulbrood (AFB), is the primary bacterial pathogen affecting honeybees and beekeeping. The main methods for controlling AFB are incineration of diseased colonies or prophylactic antibiotic treatment (e.g. tylosin), neither of which is fully satisfactory. The search for superior means for controlling AFB has led to an increased interest in the natur