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A differential difference comparator for multi-step A/D converters

The proposed Differential Difference Comparator (DDC) provides easy linear voltage summing/subtraction and comparison functions via current operation. The speed of this unconventional comparator drastically improved since there is no feedback loop and coupling capacitors needed to maintain the linearity. The linear input range is also enlarged by the common mode compression. The principle, design

Current approaches to measuring human islet-antigen specific T cell function in type 1 diabetes.

Type 1 diabetes (T1D) is an autoimmune disease caused by the T cell-mediated destruction of the pancreatic insulin-producing beta cells. Currently there are no widely accepted and standardized assays available to analyse the function of autoreactive T cells involved in T1D. The development of such an assay would greatly aid efforts to understand the pathogenesis of T1D and is also urgently require

Ultrafast carotenoid band shifts: Experiment and theory

The ultrafast carotenoid band shift upon excitation of nearby bacteriochlorophyll molecules was studied in three different light harvesting complexes from purple bacteria. The results were analyzed in terms of changes in local electric field of the carotenoids. Time dependent density functional theory calculations based on known and model structures led to good agreement with experimental results,

Cryptanalysis of the "grain" family of stream ciphers

Let us have an NLFSR with the feedback function g(x) and an LFSR with the generating polynomial f(x). The function g(x) is a Boolean function on the state of the NLFSR and the LFSR, at any time instance t. Whenever the LFSR has good statistical properties, it is used for controlling the randomness of the NLFSR's state machine. In this paper we define and study the general class of "Grain" family o

Political Consumerism and the Transition Towards a More Sustainable Food Regime Looking Behind and Beyond the Organic Shelf

Abstract in Undetermined In media, policymaking and research, increasing attention is drawn to the phenomenon of ‘green political consumerism’, referring to consumerrelated practices that are based on concerns beyond the traditional criteria of product quality and price. Political consumerism is about expressing non-economic values, that is, values beyond the direct, economic self-interest of cons

Pathogenesis of autoimmune diseases: antibodies against transglutaminase, peptidylarginine deiminase and protein-bound citrulline in primary Sjögren's syndrome, multiple sclerosis and Alzheimer's disease.

Coeliac disease (CD) is becoming a model for understanding the pathogenesis of autoimmune disorders. In CD, antibodies against transglutaminase 2 (TG2) and specific residues of gliadins have been identified. A similar situation is seen in rheumatoid arthritis (RA) with both anti-citrullinated protein antibodies (ACPA) and auto-antibodies against the citrullinating enzyme, peptidylarginine deiminas

The FOXO3A rs2802292 G-Allele Associates with Improved Peripheral and Hepatic Insulin Sensitivity and Increased Skeletal Muscle-FOXO3A mRNA Expression in Twins.

Objective: The minor G allele of FOXO3A rs2802292 has been associated with longevity. We aimed to investigate whether a phenotype related to healthy metabolic aging could be identified in individuals carrying the longevity-associated FOXO3A rs2802292 G allele. Research Design and Methods: rs2802292 was genotyped in a phenotypically well-characterized population of young and elderly twins (n = 190)

Plasma Copeptin, A Unifying Factor behind the Metabolic Syndrome.

Context: Arginine vasopressin (AVP) is known to affect liver glycogenolysis, insulin, and glucagon secretion and pituitary ACTH release. We previously showed that high copeptin, the stable C-terminal fragment of AVP prohormone, is independently associated with hyperinsulinemia and future development of diabetes mellitus. Objective: The objective of the study was to examine whether plasma copeptin

Adaptive Tracking of Non-linear Dynamic Plants, Using the U-model

Adaptive tracking of non-linear dynamic plants is currently an important area of research. The main difficulty being felt by the research community is the lack of a general modelling framework that can facilitate synthesis of a simplistic control law while being capable of providing accurate approximation of non-linear systems. In this study a novel technique based on the control-oriented U-model

Concomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma.

Hibernomas are benign tumors with morphological features resembling brown fat. They consistently display cytogenetic rearrangements, typically translocations, involving chromosome band 11q13. Here we demonstrate that these aberrations are associated with concomitant deletions of AIP and MEN1, tumor suppressor genes that are located 3 Mb apart and that underlie the hereditary syndromes pituitary ad

Tryggheten inför rätta : Om rätten till förtidspension enligt förvaltningsdomstolarna under tre decennier

Popular Abstract in Swedish Under de senaste åren har förtidspensionen och dess funktionssätt hamnat i fokus för den politiska debatten. Behovet av en förnyad, anpassad och mer ekonomiskt hållbar försäkring har framförts i politiska diskussioner, offentliga utredningar och inom forskarsamhället sedan början av 1990-talet. Samtidigt har kritik riktats mot att det finns skillnader och glidningar i fThe Swedish disability pension program has been a recurring topic for political debate. Through the years the need for an adjusted and financially stable insurance has been commented on by politicians and by scholars. Numerous government reports have tackled both the costs of the program and the growing number of people granted disability pensions. During the last ten years the disability pension

More Fish, more Mahasoa? A Quantitative Analysis of Food Security & Poverty Reduction in Rural Small-scale Aquaculture in Madagascar

The role of food-producing sectors such as agriculture and aquaculture in the development process is debated and while some consider industrial production to be the answer, others suggest that small-scale production can also make contributions to poverty reduction and food security. This thesis aims to shed light on these relationships by performing quantitative analyses of the small-scale freshwa

Samtal kring en gammal tysk lära: En studie av tro och gärningar hos Theologia Germanica och Martin Luther i ekumenikens tecken

The aim of this thesis is to investigate if the Lutheran heritage, represented by a comparison between early Lutheran writings and Luther’s source of inspiration Theologia Germanica, can provide a starting point for potentially unifying dialogues within Christian circles. The background of this pursuit of unity is the ecumenical problem of the seemingly opposite views of how faith and deeds relate

Integration of Modelling Environments to an ÄKTA System

Automation: Optimering av din tid Tänk dig att du har fått en deadline på ditt nya projekt. Ditt arbete för projektet beror helt på din praktiska noggrannhet och tidsoptimering, samtidigt så ska du lämna in massvis med pappersarbete. Du har en tuff tid framför dig ifall du ska klara detta på egen hand inom tidsramen. Här kommer automatisering in i bilden. Det noggranna och tidskrävande arbetet soAutomated information flow is an important way of optimizing the time used for analyzing processes. Other added benefits are that in a well-made automated system, the probability of human error diminishes because less liability is put on the person to manually transport and utilize the data. This notion of automation can be applied to the field of chromatography. This thesis investigates the poss

From Cash to Crop

This study explores the nexus between financial inclusion and agricultural productivity in Tanzania, where agriculture is a key sector for the nation's economy and inclusive growth. Vulnerable to climate change, the sector faces productivity challenges due to rain anomalies and rising temperatures. Previous studies have highlighted financial inclusion as crucial for reducing vulnerability at t

Elements of Wellbeing - a multi sensory approach towards healthy living by using the natural rhythm of the sun

Since we as architects have an influence on people‘s everyday routines in their homes, it is important to understand the most natural human needs in order to create spaces for a healthy and joyful life, which are strongly connected to the environment. The human body is a complex organism which is strongly influenced by its immediate surroundings, whilst responding with circadian rhythms to the eve

The Role of Brand Logics in Shaping the Success of Brand Extensions: Apple vs. Colgate

Purpose: The purpose of this study is to investigate the impact of brand logics on the success of brand extensions. Methodology: This study has examined two different case studies to better understand the effect of brand logic. An extensive literature review was done on “brand logics”, specifically Unique Selling Proposition (USP) and the Golden Circle, “brand extensions” as well as “brand identit

Genetic Variation in the Glucose-Dependent Insulinotropic Polypeptide Receptor Modifies the Association between Carbohydrate and Fat Intake and Risk of Type 2 Diabetes in the Malmo Diet and Cancer Cohort.

Context:A common genetic variant (rs10423928, A-allele) in the glucose-dependent insulinotropic polypeptide receptor gene (GIPR) is associated with decreased insulin secretion. Glucose-dependent insulinotropic polypeptide is secreted after food consumption and gipr knockout mice fed a high-fat diet are protected against obesity and disturbances in glucose homeostasis. Objective:Our objective was

Deduction of VAT on immovable property -Fiscal neutrality and Art 168a

The thesis starts with a description of the background to the change of the rules on deduction of VAT on mixed use immovable property through the insertion of Article 168a in the RVD. The reason according to the Amendment is to promote equity and to prevent unjustified cash-flow advantages granted to taxable persons who use acquire immovable property, deduct full input VAT and then pay it back o