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Imaging the spray formation region of atomizing sprays is particularly challenging due to the presence of a variety of irregular liquid structures such as ligaments, liquid blobs, droplets, liquid sheets and a possible liquid core. The number and concentration of those liquid bodies dictate the presence of liquid/air interfaces, which are responsible to undesired scattering effects. The resulting
Although the use of location-based data (location coupled with semantic information) within Geographical Information Systems (GIS) and from Earth Observation (e.g. satellite) sources has been long established for decision makers, this has only recently been reflected in the construction sector with a more recent move from Computer Aided Design (CAD) to Building Information Modelling. BIM has opene
This paper describes the assessment of the cost efficiency of risk mitigation measures for terrorist attacks with Improvised Explosive Devices (IEDs) for an iconic bridge structure. The assessment is performed with a decision theoretical framework building upon very recent advances in the framework of the COST Action TU1402 on Quantifying the Value of Structural Heath Monitoring. The decision scen
The fatigue deterioration modeling for welded steel structures subjected to high cycle fatigue is presented in the current document. The aim of this paper is to formulate approaches based on actual research results for the phases fatigue crack initiation, fatigue propagation and fatigue failure. The physical characteristics of the approaches are discussed in combination with the associated uncerta
A reliability-based approach to inspection planning for welded steel structures subjected to high cycle fatigue is presented in the current document. Inspections are an effective means to control the progress of fatigue deterioration and the presented approach allows to determine the minimum required inspection effort so that the considered structure complies with the given risk acceptance criteri
PURPOSE: It is unclear whether plasma homocysteine (Hcy) has a direct noxious impact on the cardiovascular (CV) system or whether its association with cardiovascular events (CVEs) is mediated by established risk factors. To explore the role of Hcy in CV impairment, the study evaluated cross-sectional relationships between plasma Hcy and indices of CV organ damage together with the associations of
Otitis media with effusion (OME) is a common inflammatory disease, primarily affecting children. OME is defined as a chronic low-grade inflammation of the middle ear (ME), without any signs of infection and with effusion persisting in the ME for more than three months. The precise pathogenesis is, however, not fully understood. Here, we comprehensively characterized and compared the host immune re
Olyckor vid vägarbetszoner är ett ihållande trafiksäkerhetsproblem i många europeiska länder. IRIS-projektet (Incursion Reduction to Increase Safety in road work zones) finansierat av CEDR samlade in information om bästa praxis inom trafikledning vid vägarbetsplatser. En analys av olyckor i arbetszonen och en översyn av bästa praxis gjordes. Psykologiska problem för att förbättra säkerheten i arbeAccidents nearby work zones are a persistent road safety problem in many European countries. The Conferenceof European Directors of Roads (CEDR) has initiated and finances the IRIS project (Incursion Reduction toIncrease Safety in road work zones) with the aim to collect and share information about best practices in temporarytraffic management at road works. An analysis of work zone accidents and
Background and purpose — Clindamycin has not been compared with other antibiotics for prophylaxis in arthroplasty. Since 2009, the Swedish Knee Arthroplasty Register (SKAR) has been collecting information on the prophylactic antibiotic regime used at every individual operation. In Sweden, when there is allergy to penicillin, clindamycin has been the recommended alternative. We examined whether the
Urban environments pose novel challenges, as well as opportunities, for urban-dwelling wildlife. Although differences have been reported in several phenotypic traits (e.g. morphology, physiology and behaviour) between urban and rural populations, it is poorly understood whether this affects individual fitness. Telomere dynamics are posited as one possible mechanism underlying senescence and mortal
Spatial data are playing an increasingly important role in watershed science and management. Large investments have been made by government agencies to provide nationally-available spatial databases; however, their relevance and suitability for local watershed applications is largely unscrutinized. We investigated how goodness of fit and predictive accuracy of total phosphorus (TP) concentration m
The University of Vermont College of Medicine and the Vermont Lung Center, in collaboration with the NHLBI, Alpha-1 Foundation, American Thoracic Society, European Respiratory Society, International Society for Cell Therapy, and the Pulmonary Fibrosis Foundation, convened a workshop, "Stem Cells and Cell Therapies in Lung Biology and Lung Diseases, " held July 29 to August 1, 2013 at the Universit
The mechanisms underlying M. fortuitum-induced pathogenesis remains elusive. Using headkidney macrophages (HKM) from Clarias gariepinus, we report that TLR-2-mediated internalization of M. fortuitum is imperative to the induction of pathogenic effects. Inhibiting TLR-2 signalling alleviated HKM apoptosis, thereby favouring bacterial survival. Additionally, TLR-2-mediated cytosolic calcium (Ca2+)c
Background Genome-wide association studies have identified >1000 genetic variants cross-sectionally associated with blood pressure variation and prevalent hypertension. These discoveries might aid the early identification of subpopulations at risk of developing hypertension or provide targets for drug development, amongst other applications. The aim of the present study was to analyze the associat
The presented work describes a computational method for carrying out a detailed and thorough examination of the flash temperature rise (i.e. the local’instantaneous’ temperature increase on a contact interface, due to frictional effects) present on the tooth flanks of a polymer gear pair, composed of a combination of POM and PA66 thermoplastics, during a given meshing cycle. The method involves a
The pharmaceutical approach to skin disease has been hugely successful, but despite effective drugs being available and used, there are still vast numbers of people who continue to have some level of persisting skin disease and continue to experience quality of life (QoL) impairment. So the question that needs to be answered, while we await further advances in our drug-based armamentarium, is how
Platelets are the primary cellular mediators of hemostasis and this function firmly acquaints them with a variety of inflammatory processes. For example, platelets can act as circulating sentinels by expressing Toll-like receptors (TLR) that bind pathogens and this allows platelets to effectively kill them or present them to cells of the immune system. Furthermore, activated platelets secrete and
Solar energy simulations are used to quantify the potential of the passive use (daylight, solar gains) and the active use (photovoltaics and solar thermal) of solar energy. The simulations can be performed at different scales e.g. buildings, neighbourhoods and cities, with different requirements on the data. For example, for the neighbourhood simulations we need simplified building geometries that
