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The Development of Severe Neonatal Alloimmune Thrombocytopenia due to Anti-HPA-1a Antibodies Is Correlated to Maternal ABO Genotypes

Background. Maternal alloantibodies against HPA-1a can cross placenta, opsonize foetal platelets, and induce neonatal alloimmune thrombocytopenia (NAIT). In a study of 100, 448 pregnant women in Norway during 1995-2004, 10.6% of HPA-1a negative women had detectable anti-HPA-1a antibodies. Design and Methods. A possible correlation between the maternal ABO blood group phenotype, or underlying genot

...de dödas kroppsliga forms uppståndelse och ett evigt liv. - En undersökning av Origenes syn på kroppens uppståndelse

In this essay, I will examine what Origen of Alexandria believed about the resurrection of the body. Origen was condemned as a heretic at the Second Council of Constantinople in 553, one of the main reasons for this was that he was said to deny the physical resurrection of the body. Due to the condemnation of Origen, the work of copying his works was also stopped, with the result that many of Orig

Decomposing health: tolerance and resistance to parasites in animals.

Plant biologists have long recognized that host defence against parasites and pathogens can be divided into two conceptually different components: the ability to limit parasite burden (resistance) and the ability to limit the harm caused by a given burden (tolerance). Together these two components determine how well a host is protected against the effects of parasitism. This distinction is useful

Biological effects of 2-oxoglutarate with particular emphasis on the regulation of protein, mineral and lipid absorption/metabolism, muscle performance, kidney function, bone formation and cancerogenesis, all viewed from a healthy ageing perspective state of the art - review article

The fact that men and women are living longer than they have ever done before is something in which we can all rejoice. However, the process of ageing is associated with changes in skeletal, muscular, gastrointestinal, neural hormonal and metabolic processes that seriously affect an individual's performance and quality of life. Indeed, Such changes can be contributory to a loss of independence in

Polyandry and alternative mating tactics

Many species in the animal kingdom are characterized by alternative mating tactics (AMTs) within a sex. In males, such tactics include mate guarding versus sneaking behaviours, or territorial versus female mimicry. Although AMTs can occur in either sex, they have been most commonly described in males. This sex bias may, in part, reflect the increased opportunity for sexual selection that typically

Metaphors, Law and Digital Phenomena: the Swedish pirate bay court case

This article uses conceptual metaphor theory to develop the concept of ‘skeumorphs’ (reuse of old concepts for new phenomena) in order to analyse the Swedish The Pirate Bay court case. In line with conceptual metaphor theory, which states that abstract thinking is largely metaphorical, the article argues that this is true also for digital phenomena that, thus, are largely understood through metaph

Decoding of individuated finger movements using surface EMG and input optimization applying a genetic algorithm.

In this paper we present surface electromyographic (EMG) data collected from 16 channels on five unimpaired subjects and one transradial amputee performing 12 individual finger movements and a rest class. EMG were processed using a traditional Time Domain feature-set and classifiers: a Linear Discriminant Analysis (LDA) a k-Nearest Neighbors (k-NN) and Support Vector Machine (SVM). Using continuou

Transcriptional analysis of mantle cell lymphoma - a global search for cellular origin and therapeutic targets

This thesis is based upon four original papers describing the characterisation of mantle cell lymphoma (MCL) tumours and cell lines in comparison with different populations of normal B cells. Gene expression profiling, which were used in the studies, has during recent years developed as an important tool in characterisation of different types of malignancies. In this thesis, the technique is used

Syria from Reform to Revolt : Vol. 2, Culture, Society, and Religion

As Syria’s anti-authoritarian uprising and subsequent civil war have left the country in ruins, the need for understanding the nation’s complex political and cultural realities remains urgent. The second of a two-volume series, Syria from Reform to Revolt: Culture, Society, and Religion draws together closely observed, critical and historicized analyses, giving vital insights into Syrian society t

Iterative Optimal Control of Liquid Slosh in an Industrial Packaging Machine

Presents an iterative approach to optimal control when modeling errors are present. The problem considered is movement of open containers containing liquid in an industrial packaging machine. The goal is to move as fast as possible without too much slosh. There is no measurement of the slosh available in the machine, therefore open loop control via the acceleration reference is the only possibilit

Transforming Growth Factor-b, Regulatory functions on normal lymphocytes and tumor outgrowth Regulatory functions on normal lymphocytes and tumor outgrowth

Popular Abstract in Swedish För att en multicellulär organism som männinskan ska kunna fungera måste celldelningen strikt kontrolleras. Protein som reglerar celldelning på cellulär nivå kallas för "tillväxtfaktorer". Vi har studerat ett sådant protein som kallas för transforming growth factor-beta (TGF-b). Namnet TGF-b kommer sig utav att detta protein kan transformera (omvandla) epiteliala njurceTransforming growth factor-beta (TGF-b) is a well-characterised growth regulatory factor, which acts on most cell types. This thesis has focused on the regulatory roles of TGF-b on normal lymphocytes. One interesting finding is that TGF-b acts both costimulatory and inhibitory on T-lymphocytes. The costimulatory effect depends on the presence of monocytes and is mediated by these cells. Furthermor

I den värld vi drömmer om: utopin i Elin Wägners trettiotalsromaner

Popular Abstract in Swedish ”Vi kommo överens om att möten innehålla alla livets möjligheter, och att en människa som levat mycket vet mycket om möten om hon alls vet någonting.” Så uttalar den kvinnliga huvudpersonen i Mannen vid min sida (1933) sin övertygelse efter mötet med älskaren. Denna avhandling fokuserar mötet i Elin Wägners trettiotalsromaner. Genom att analysera detta vill avhandlingsfThe aim of this present thesis is to present the Utopian scheme in Elin Wägner’s novels of the nineteen-thirties: Dialogen fortsätter (1932) (“The Dialogue Continues”), Mannen vid min sida (1933) (“The Man by my Side”), Genomskådad (1937) (“Unmasked”) and Hemlighetsfull (1938) (“Mysterious”). With her authorship Wägner was aiming for a new social order, a radical change, polväxling (a shift of pol