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Suddenly at risk: Older adults’ changes in everyday life early on during the COVID-19 pandemic

ABSTRACT:Introduction / Rationale: From the onset of the COVID-19 pandemic, social distancing was recommended for adults 70 years and older (70+) in Sweden. From an outside view, they then became deprived of possibilities to engage in meaningful activities. However, as meaning is highly subjective, we need to listen to older adults’ voices to really know.Objectives: To explore how adults 70+ exper

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In this study, we discuss Swedish travelers from different backgrounds during their visits to Greece and Asia Minor in the 18th century. Besides their scientific interests, they write about their impressions of the Greeks and other people in the area, as well as education, language, religion, local economy, culture, and social life. They have good knowledge of ancient Greek history and the Greek l

Conflict, violence, and warfare among early farmers in Northwestern Europe

Bioarchaeological evidence of interpersonal violence and early warfare presents important insights into conflict in past societies. This evidence is critical for understanding the motivations for violence and its effects on opposing and competing individuals and groups across time and space. Selecting the Neolithic of northwestern Europe as an area for study, the present paper examines the variati

Adherence to the EAT-Lancet diet and risk of coronary events in the Malmo Diet and Cancer cohort study

BACKGROUND: The EAT-Lancet Commission proposed a globally environmentally sustainable dietary pattern featuring mainly plant-based foods in 2019. However, evidence on this dietary pattern in preventing coronary events is minimal.OBJECTIVE: We aimed to examine the association between the EAT-Lancet diet and risk of coronary events.METHODS: The Malmö Diet and Cancer cohort study (recruited between 1

Complexes of Charged-Neutral Block Copolymers and Surfactants : Process-Dependent Features and Long-Term Stability of Their Aqueous Dispersions

Aqueous dispersions of charged-neutral block copolymers (poly(acrylamide)-b-poly(acrylate)) complexed with an oppositely charged surfactant (dodecyltrimethylammonium) have been prepared by different approaches: the simple mixing of two solutions (MS approach) containing the block copolymer and surfactant, with their respective simple counterions, and dispersion of a freeze-dried complex salt prepa

The dragon simulations: globular cluster evolution with a million stars

Introducing the dragon simulation project, we present direct N-body simulations of four massive globular clusters (GCs) with 106 stars and 5 per cent primordial binaries at a high level of accuracy and realism. The GC evolution is computed with nbody6++gpu and follows the dynamical and stellar evolution of individual stars and binaries, kicks of neutron stars and black holes (BHs), and the effect

The importance of food for endotoxemia and an inflammatory response

Bacterial endotoxin is a potent inflammatory antigen abundant in the human intestine. Endotoxins circulate in the blood at low concentrations in all healthy individuals. Elevated levels of circulatory endotoxins may cause inflammation with the development of chronic disease, either affecting metabolism, neurological disease, or resistance to viral and bacterial infections. The most important endot

Maternal Immunoglobulins in Infants—Are They More Than Just a Form of Passive Immunity?

In the present review, we highlight the possible “extra-immunological” effects of maternal immunoglobulins (Ig) transferred to the blood circulation of offspring, either via the placenta before birth or via the colostrum/milk across the gut after birth in different mammalian species. Using the newborn pig as a model, since they are naturally born agammaglobulinemic, intravenously (i.v.) infused pu

The fine-grained complexity of computing the tutte polynomial of a linear matroid

We show that computing the Tutte polynomial of a linear matroid of dimension k on kO(1) points over a field of kO(1) elements requires kΩ(k) time unless the #ETH-a counting extension of the Exponential Time Hypothesis of Impagliazzo and Paturi [CCC 1999] due to Dell et al. [ACM TALG 2014]-is false. This holds also for linear matroids that admit a representation where every point is associated to a

Ventricular-arterial coupling as a potential therapeutic target in diabetes

Patients with type 2 diabetes (T2D) are at high risk of cardiovascular complications. Novel anti-diabetic medications such as sodium-glucose cotransporter-2 inhibitors (SGLT-2i) and Glucagon-like peptide-1 receptor agonists (GLP-1RA) have been shown to possess cardiac and renal protective effects beyond their ability to lower plasma glucose. Use of SGLT-2i and GLP-1RA in patients with T2D and hear

Community Energy in the Eastern Baltic Sea Region: From Standstill to First Steps

This chapter aims to explore community energy (CE)—energy communities that are established and run by private citizens—in four Eastern European countries. The chapter first analyses general contextual conditions supporting the diffusion of CE initiatives in the Baltic Sea Region. Subsequently, it reports the findings of four case studies from Estonia, Latvia, Lithuania, and Poland illustrating som

Stability-aware integrated routing and scheduling for control applications in Ethernet networks

Real-time communication over Ethernet is becoming important in various application areas of cyber-physical systems such as industrial automation and control, avionics, and automotive networking. Since such applications are typically time critical, Ethernet technology has been enhanced to support time-driven communication through the IEEE 802.1 TSN standards. The performance and stability of contro

Roman ports in the lower Tiber valley : computational approaches to reassess Rome's port system

This paper presents an innovative study of the port system of Rome in Imperial times through the application of an integrated approach to both archaeological analysis and material evidence. Specifically, it seeks to provide a more complete contextualization and understanding of the port system of Rome by focusing on the exploration of the physical geography of the river Tiber and its transformatio

The future of sustainability projects: Flights of fancy or a threnody to a lost age?

Just like a living organism, also the project has an anatomy, a life span and a purpose. A project has its given actors, given timeframe and phases, and a given goal. Towards the project’s completion, all these factors must intertwine perfectly, otherwise the project’s success will be challenged. Uncovering how these intricacies are held in place has been the epistemological foundation of this boo

Neutrophil FcγRIIA availability is associated with disease activity in systemic lupus erythematosus

Background: Immune complexes (ICs) are detectable in a variety of inflammatory diseases, including systemic lupus erythematosus (SLE), reflecting autoantibody binding to antigens. Though ICs are the main contributors to disease pathogenesis through FcγR-mediated inflammation and organ damage, IC levels are not part of the clinical assessment of SLE. The aim of this study was to explore the clinica

Survival in 31 670 patients with thin melanomas : a Swedish population-based study

BACKGROUND: The incidence of cutaneous malignant melanoma (CMM) continues to increase in most countries worldwide and the majority are diagnosed with thin tumours (≤ 1 mm).OBJECTIVES: The aim of the present study was to investigate the melanoma-specific survival (MSS) as well as conditional MSS (CMSS) in patients with thin CMM in Sweden.PATIENTS AND METHODS: Clinical and histological parameters we

High-Sensitivity Assessment of Phagocytosis by Persistent Association-Based Normalization

Phagocytosis is measured as a functional outcome in many research fields, but accurate quantification can be challenging, with no robust method available for cross-laboratory reproducibility. In this study, we identified a simple, measurable parameter, persistent prey-phagocyte association, to use for normalization and dose-response analysis. We apply this in a straightforward analytical method, p

Understanding the origin of white dwarf atmospheric pollution by dynamical simulations based on detected three-planet systems

Between 25 and 50 per cent of white dwarfs (WD) present atmospheric pollution by metals, mainly by rocky material, which has been detected as gas/dust discs, or in the form of photometric transits in some WDs. Planets might be responsible for scattering minor bodies that can reach stargazing orbits, where the tidal forces of the WD can disrupt them and enhance the chances of debris to fall on to t