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Interactions in metal toxicology

Human exposures to metals and metalloids such as arsenic frequently occur as mixtures, and hence it is important to consider interactions among these elements in terms of both mechanisms of action and for risk assessment purposes. Interactions among these elements may produce additive, synergistic/potentiative, or antagonistic effects that may be manifested as direct cellular toxicity (necrosis or

Indiscernibility and Form : The Design of Unit C as a Critical Inquiry into the Guidelines for Historical Preservation

This article explores the intersection between the indiscernible forces of urbanisation and the materialisation of architectural form. Taking the design of architectural concept for an Accessory Dwelling Unit (ADU) at Råå in Sweden as an applied research project, the article argues that new techniques are needed to analyse interactions between artistic intentionality and indiscernible forces, and

Concepts and pathways towards a carbon-neutral heavy industry in the German federal state of North Rhine-Westphalia

The German federal state of North Rhine-Westphalia (NRW) is home to important clusters of energy-intensive basic materials industries. 15 % of the EU's primary steel as well as 15 % of high-value base chemicals are produced here. Together with refinery fuels, cement, lime and paper production (also overrepresented in NRW) these are the most carbon-intensive production processes of the industrial m

Work life balance and taxation in the Netherlands

In the Netherlands, the role of the woman in society has changed drastically in the past century. Furthermore, over the past 50 years, marriage between man and woman lost its dominant position to alternative forms of cohabitation. These developments in society and civil law are also reflect-ed in the Dutch Personal Income Tax Act (PITA) and the Dutch Gift and Inheritance Tax Act (GITA) and will be

Comprehensive echocardiographic imaging of atrioventricular valves in children with atrioventricular septal defect : Accuracy of 2D and 3D imaging and reasons for disagreement

OBJECTIVE: To compare the accuracy and reasons for disagreement of two-dimensional (2D) and three-dimensional (3D) echocardiography findings in the assessment of the atrioventricular valve complex in patients with atrioventricular septal defect. METHODS: A total of 20 children (mean age 8 months) with atrioventricular septal defect were enrolled prospectively into this study. The accuracy of and t

Serine, glycine, and threonine

Amino acids are not only indispensable for protein synthesis but also play important cellular functions. In this chapter, the central nervous system (CNS) functions of serine, glycine, and threonine are discussed. Both the specific functions of the aforementioned amino acids and the functions of their derivatives are reviewed in relation to brain development and neurotransmission. In particular, f

Identifying stellar streams in Gaia DR2 with data mining techniques

Streams of stars from captured dwarf galaxies and dissolved globular clusters are identifiable through the similarity of their orbital parameters, a fact that remains true long after the streams have dispersed spatially. We calculate the integrals of motion for 31 234 stars, to a distance of 4 kpc from the Sun, which have full and accurate 6D phase space positions in the Gaia DR2 catalogue. We the

Purine Metabolites and Carnitine Biosynthesis Intermediates Are Biomarkers for Incident Type 2 Diabetes

CONTEXT: Metabolomics has the potential to generate biomarkers that can facilitate understanding relevant pathways in the pathophysiology of type 2 diabetes (T2DM). METHODS: Nontargeted metabolomics was performed, via liquid chromatography-mass spectrometry, in a discovery case-cohort study from the Malmö Preventive Project (MPP), which consisted of 698 metabolically healthy participants, of whom

Representation in Mary Wollstonecraft’s Political Philosophy

For Mary Wollstonecraft, the moral purpose of government is to act on the principle of equality and protect the weak against the fact of inequality. The political day-to-day is characterized by classes and groups with competing interests, some more powerful than others. Wollstonecraft was a republican thinker and so it is reasonable to expect in her writings a notion of political society as repres

En möjlig värld: En tematisk studie av Lars Gustafssons 1990-talsromaner

Popular Abstract in Swedish "En möjlig värld" behandlar Lars Gustafssons (f. 1936) romaner "Historien med hunden" (1993), "Tjänarinnan" (1996) och "Windy berättar" (1999), vilka framstår som en central del i det omfattande författarskapet. Genom romanerna löper som en röd tråd sökandet efter en moralfilosofiskt och ontologiskt möjlig värld - ett sökande som här tydliggörs och analyseras. Med hjälp"En möjlig värld" explores how questions of moral standards and ontology are discussed explores how questions of moral standards and ontology are discussed and represented in three of Lars Gustafsson's novels in a search for a world that is conceivable - in terms of moral philosophy, as well as ontology. Initially, a theoretical foundation is constructed, based on the assumption that fictional tex

Biodiversity Conservation and Ecosystem Services Provision: A Tale of Confused Objectives, Multiple Market Failures and Policy Challenges

Abstract in UndeterminedIn recent years, there has been a marked proliferation in the literature on economic approaches to ecosystem management, which has created a subsequent need for real understanding of the scope and the limits of the economic approaches to ecosystems and biodiversity. Within this Handbook, carefully commissioned original contributions from acknowledged experts in the field ad

Triarylamine on Nanocrystalline TiO2 Studied in its Reduced and Oxidized State by Photoelectron Spectroscopy

The electronic and molecular structures of an electrochemically reduced and oxidized triarylamine layer (((3-ethyl(p-N,N-dimethylamino)phenyl)amino)propyl-1-phosphonic acid) adsorbed on a nanocrystalline TiO2 film have been investigated. Photoelectron spectroscopy (PES) measurements on electrochemically prepared surfaces and density functional theory (DFT) calculations for the free triarylamine mo

The Fragility of Religious Freedom

One implication of freedom of religion is that the State must accept a variety of religious beliefs and practices. Yet, not everything can be accepted. One way of dealing with such a conflict is to state that freedom of religion is absolute in so far that it does not infringe upon some other more important value. Another way is to limit what is considered ‘religious.’ Both these ways are insuffici