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CO-binding protein (C4BP) is a protein acting as a complement inhibitor and a carrier protein for anticoagulant protein S. Previously, we reported that the in vivo clearance of C4BP involves CD91, and that a CD91-interactive site overlaps the heparin-binding site within COP alpha-chains [26]. Here, we investigated the C4BP-CD91 interaction in more detail. Binding of C4BP to CD91 was unaffected by

The diagnosis of syphilis is most frequently dependent on antibody detection with serological assays. Assays for both treponemal and non-treponemal antibodies are needed to provide a sensitive and specific diagnosis. For decades, a first screening has been done with non-treponemal assays, followed by treponemal. However, in recent years, following laboratory automation, the reverse sequence screen

IgA nephropathy (IgAN) is characterized by mesangial cell proliferation and extracellular matrix expansion associated with immune deposits consisting of galactose-deficient polymeric IgA1 and C3. We have previously shown that IgA-binding regions of streptococcal M proteins colocalize with IgA in mesangial immune deposits in patients with IgAN. In the present study, the IgA-binding M4 protein from

Despite an abundance of peptides inside a cell, only a small fraction is ultimately presented by HLA-I on the cell surface. The presented peptides have HLA-I allomorph-specific motifs and are restricted in length. So far, detailed length studies have been limited to few allomorphs. Peptide-HLA-I (pHLA-I) complexes of different allomorphs are qualitatively and quantitatively influenced by tapasin t

Some concerns still have not been resolved about the long-term safety of drug-eluting stents (DES) in patients with acute STEMI.

A "complex salt" of cetyltrimethylammonium (CTA(+)) with short (30 repeating units) polyacrylate (PA(-)) counterions has been synthesized. The phase diagrams of its aqueous mixtures with either the surfactant cetyltrimethylammonium acetate (CTAAc), or the polyelectrolyte NaPA, have been studied by visual inspection through crossed polarizers and by small-angle X-ray scattering. Both of the ternary

Eae5 in rats was originally identified in two F-2 intercrosses, (DA x BN) and (E3 X DA), displaying linkage to CNS inflammation and disease severity in experimental autoimmune encephalomyelitis (EAE), respectively. This region overlaps with an arthritis locus, Pia4, which was also identified in the (E3 X DA) cross. Two congenic strains, BN.DA-Eae5 and BN.DA-Eae5.R1, encompassing the previously des

Popular Abstract in Swedish Under de senaste decennierna har det pågått en intensiv kamp om dramapedagogikens innehåll. Den har i betydande utsträckning förts på nordiskt plan. Dramaläraren och lärarutbildaren Viveka Rasmusson visar att denna debatt om dramaämnet och dess utveckling med fördel kan studeras i den nordiska tidskriften Drama. Under större delen av sjuttiotalet var Drama ett gemensamtBased on the Nordic dramapedagogic journal Drama during the period 1965-1995 the thesis analyses Nordic dramapedagogy and the dramatheoretical debate of the subject drama, which entered Nordic school curriculums in the sixties and the seventies. During the period a struggle was fought by predecessors from different aestethic and pedagogical directions concerning the definition of the subject. The

Vid den nordiska konferensen ”Teaching bioethics” illustrerade transplantationskirurgen Nils H. Persson och jag hur en dialogpedagogisk metod kan belysa en frågeställning på ett sätt som är svårt för en ensam lärare. Nils H. Persson diskuterade bland annat den stora skillnaden i frekvens av organdonationer mellan de nordiska länderna, mindre än 15 PMP (per million population), och Spanien, mer än

In this paper, tone mapping operations based on the nonlinear successive Mean Quantization Transform (SMQT) are proposed in order to convert high dynamic range images to low dynamic range images. A SMQTbased tone mapping applied on the luminance channel is derived as well as a SMQT-based method working directly on all RGB channels. Both methods are compared to other state-of-the-art methods and pr

We have in this study analyzed the function of the murine Joining chain (J chain) in vivo. J chain is a polypeptide found in sera and secretions in complex with pentameric IgM and dimeric IgA. J chain is expressed in terminally differentiated B lymphocytes and needed for the transport of dimeric IgA and pentameric IgM over mucosal surfaces via the poly Ig receptor. A mouse deficient for J chain wa

This article outlines an experimental and numerical study of the long-term interaction between silica fume and Portland cement in concrete subjected to air, water or sealed curing. For this purpose about 2000 kg of eight qualities of concrete were studied at 4 different ages each over a period of 90 months. Half of the concretes contained silica fume. Parallel studies of strength, hydration and in

The article explores influences from Old Testament and Gnostic sources upon Japanese video game culture and also discusses the relationship between the player and the played in said games - from a perspective rooted in an exegesis of such texts. It also concerns the pop-culture climate of the 1990s and early 2000s in this context.