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Popular Abstract in Swedish Cellerna I vårt immunförsvar hjälper oss att eliminera olika typer av infektioner orsakade av parasiter, bakterier och virus. Ibland klarar dessa celler även av att ta bort tumörceller, kroppsegna celler som börjat att dela på sig okontrollerbart. Det måste betyda att cellerna i immunförsvaret kan se skillnad på kroppsegna celler och främmande celler och strukturer (antThe present study deals with natural killer (NK) T cells restricted to the antigen presenting molecule CD1d. NKT cells have been suggested to play a role in many diverse immunological situations such as clearance of different pathogens, protection against certain tumors, regulation of autoimmune reactions and as a link between innate and adaptive immune responses. NKT cells are in many respects un

A stability criterion for nonlinear systems, derived by the first author (2000), can be viewed as a dual to Lyapunov's second theorem. The criterion is stated in terms of a function which can be interpreted as the stationary density of a substance that is generated all over the state space and flows along the system trajectories towards the equilibrium. The new criterion has a remarkable convexity

This paper presents the first results of analyzing the functions of intonation and word order in Puyuma. Puyuma is an endangered Austronesian language spoken in Taiwan. As other languages of this branch, Puyuma is verb initial and displays variations in word order, so that VOS, SVO and VSO are attested. The aim of our study is to explain these word variations. We investigate the connection between

The recruitment of antigen-specific T lymphocytes to the intestinal mucosa is central to the development of an effective mucosal immune response, yet the mechanism by which this process occurs remains to be fully defined. Here we show that the CC chemokine receptor 9 (CCR9) is selectively and functionally expressed on murine alpha(E)beta(7)(+) naive CD8alphabeta(+) lymphocytes and a subset of rece

Purpose – The purpose of this paper is to systematically and critically review the extant literature on the design of global production and distribution networks to identify gaps in the literature and identify future research opportunities. The design aspects deal with strategic and structural decisions such as: opening or closing of manufacturing plants or distribution centres, selection of locat

In this paper we present and discuss some of the lessons learnt from the completed CoLabs.eu project within the so called R3L-initiative on European Networks of Learning Regions. In the project we made some concrete social experiments in order to “make the village a virtual campus”. We start this paper by making a general introduction to the research area and by giving the motivating background to

In this article I examine whether an influential theory of mechanisms proposed by Peter Machamer, Lindley Darden and Carl Craver can accommodate polygenic effects. This theory is both interesting and problematic, I will argue, because it ascribes a central role to activities. In it, activities are needed not only to constitute mechanisms but also to perform their causal role. These putative functi

The purpose of this paper is to understand the significance of form elements through the interpretations of design sketches. These interpretations are provided by designers themselves interpreting expressive characteristics of car images, and by students interpreting the sketches of designers' morphing sequences. In the experimental investigation of the sketching process through morphing sequence

Popular Abstract in Swedish Är ledgångsreumatism en immunreaktion mot brosk? Kroppens immunförsvar bygger på ett antal olika vita blodkroppar, immunceller, som cirkulerar i blod och lymfa på spaning efter främmande och farliga "angrepp". Immuncellerna sägs svara på "angrepp", sådana immunsvar dirigeras av s k T-hjälparceller (Th-celler). Th-cellerna kommer från benmärgen, men de blir inte funktioThis thesis is based on work trying to understand the normal and pathological interactions taking place between the immune system and cartilage, specifically involving the cartilage-specific protein typ II collagen (CII). The work has been carried out in an experimental model of rheumatoid arthritis namely collagen type II induced arthritis (CIA) in mice. CIA can be triggered in mice of certain MH

Glucose-evoked insulin secretion exhibits a biphasic time course and is associated with accelerated intracellular granule movement. We combined live confocal imaging of EGFP-labelled insulin granules with capacitance measurements of exocytosis in clonal INS-1 cells to explore the relation between distinct random and directed modes of insulin granule movement, as well as exocytotic capacity. Reduci

The lifetimes of three short-lived levels belonging to the 4f(9) 6p configuration and of two long-lived levels of the 4f(9) 5d configuration of Dy iii have been measured for the first time using time-resolved laser-induced fluorescence techniques. They are in good agreement with theoretical values calculated within the framework of a pseudo-relativistic configuration interaction approximation. Usi

We report the first experimental measurements and theoretical calculations for the hyperfine splitting of the 3d(5) 4s ground state of Mn II. The hyperfine structure constants were determined using Fourier transform spectroscopy with a hollow cathode discharge lamp. The uncertainties in the magnetic dipole constants, A, are between 3 x 10(-4) and 5 x 10(-4) cm(-1). Extensive configuration interact

The European Directives on personal protective devices have increased the interest in protective and functional properties of work clothing and intensified standardisation work as well as stimulated research in areas with limited knowledge. There is a long tradition of research and information exchange in the Nordic countries on the subject. The NOrdisk KOrdineringsgruppe om BEskyttelseskläder som

What we can conclude from this study is that the state and the market are not perfect substitutes in allocating resources and sustaining economic development separately. The case of the Thai cassava industry seems to suggest that the Thai state is not benevolent, but predatory in nature. The central point is that the Thai state cannot be simply seen as weak and predatory without understanding the

In this article, we study the n - pi* electronic transition in aqueous microsolvated formaldehyde using the coupled cluster (CC) and coupled cluster/molecular mechanics (CC/MM) methods. The CC models used are the coupled cluster singles and doubles (CCSD) and the coupled cluster second-order approximate singles and doubles (CC2) methods. The CC/MM model includes electrostatic and mutual polarizati