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Background: Primary hyperparathyroidism (PHPT) is associated with cardiac disease and increased risk of all-cause and cardiovascular mortality. We investigated cardiac structural and functional parameters before and after successful parathyroidectomy in asymptomatic PHPT patients. Methods and Results: Forty-nine PHPT patients (age: 62.9 +/- 11 years, 5 men) and 48 healthy control subjects, matched

Aim: This study aims to investigate cardiac structure and function in patients with asymptomatic primary hyperparathyroidism (pHPT) and if there is any relation to severity regarding serum levels of calcium (Ca) and parathyroid hormone. Methods and Results: We consecutively included 50 patients (mean age 62.9 +/- 11 years, 45 women) with clinically diagnosed pHPT. We prospectively recruited 50 hea

Photophysical studies of pseudo-p-distyryl[2.2]paracyclophane, a model molecule of a stilbene dimer arranged in a brick-wall geometry, in tetrahydrofurane solution indicate the existence of at least two conformers in the ground state. The conformer A with the smallest optical gap of 3 eV has a short radiative lifetime of 3.3 ns, while the conformer B with an optical gap about 0.3 eV larger is much

Analytical properties of the chemical speciation method, Ion beam thermography (IBT), have been investigated. IBT combines the multi-elemental ion beam techniques PIXE, PESA, pNRA and cPESA with thermography. During thermography the sample temperature is gradually increased, causing vaporisation of chemical compounds at specific temperatures and the sample at the same time undergoes analysis by th

We present a local flow model approach for the transport and the decay of a roughly 50 year old perchloroethylene contamination at a former dry cleaning facility at Kv. Färgaren in Kristianstad that sits above the largest aquifer in Sweden. The study demonstrates an efficient workflow integrating ERT for conceptualising and calibrating a three dimensional transient, multi aquifer groundwater trans

Clinical trial results have recently demonstrated that inhibiting inflammation by targeting the interleukin-1β pathway can offer a significant reduction in lung cancer incidence and mortality, highlighting a pressing and unmet need to understand the benefits of inflammation-focused lung cancer therapies at the genetic level. While numerous genome-wide association studies (GWAS) have explored the g

The development of an N-body/hydrodynamic ‘surrogate’ model of the Milky Way (MW) – a model that resembles the MW in several key aspects after many Gyrs of evolution – would be extremely beneficial for Galactic Archaeology. Here, we present four new ‘surrogate’ models, all built with the nexus framework. The simulations contain stars, dark matter and gas. Our most sophisticated model allows gas to

A method for CdSe quantum dot (QD) sensitization of ZnO nanowires (NW) with fast adsorption rate is applied. Photoinduced excited state dynamics of the quantum dots in the case of more than monolayer coverage of the nanowires is studied. Transient absorption kinetics reveals an excitation depopulation process of indirectly attached quantum dots with a lifetime of similar to 4 ns. Photoluminescence

BackgroundHalogenated anaesthetic agents are potent greenhouse gases, but little is known about the trajectory of their use and their greenhouse gas impact on a global level. The primary aim of this study was to estimate the global greenhouse gas impact of halogenated anaesthetic agents over the preceding 10 years.

The Chemotaxis Inhibitory Protein of Staphylococcus aureus (CHIPS) binds and blocks the C5a receptor (C5aR) and formyl-peptide receptor (FPR). This way, CHIPS is a potent inhibitor of the immune cell recruitment associated with inflammation. Truncation of the protein and the introduction of mutations, shifts the expression towards the insoluble fraction of Escherichia coli, whereas the wild-type p

Birth is a dangerous and dynamic event resulting in new life, as well as in death and loss. As distinct as the birth transition may seem, it remains essentially a process. The term ‘perinatal’ defines the phase beginning in late pregnancy when the fetus has potential to survive the delivery, and ending, roughly, seven days after birth, demarcating the period when the child gradually emerges and st

Small ligaments connecting the fracture surfaces just behind a moving crack front are assumed to exist under certain conditions. The ligaments are rapidly torn as the crack advances. Inelastic straining of such ligaments influences the energy balance in the fracture process. The rapid tearing of a single ligament is studied both numerically and experimentally. An elastic visco-plastic material mod