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Abdominal compression as motion management for stereotactic radiotherapy of ventricular tachycardia

Background and purpose: Stereotactic body radiotherapy (SBRT) has emerged as a promising treatment for patients with ventricular tachycardia (VT) who do not respond to standard treatments. However, the management of respiratory motion during treatment remains a challenge. This study aimed to investigate the effect of abdominal compression (AC) on respiratory induced motion in the heart. Materials

The GNAS1 T393C polymorphism and lack of clinical prognostic value in chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease with no known single predisposing genetic factor shown in all cases. Recently, a single nucleotide polymorphism (SNP) T393C in the GNAS1 gene has been reported to have a clinical impact on CLL progression and overall survival. In order to further investigate the T393C SNP in CLL, we have genotyped 279 CLL cases and correlated

An endogenous retroviral long terminal repeat is the dominant promoter for human beta 1,3-galactosyltransferase 5 in the colon

LTRs of endogenous retroviruses are known to affect expression of several human genes, typically as a relatively minor alternative promoter. Here, we report that an endogenous retrovirus LTR acts as one of at least two alternative promoters for the human beta1,3-galactosyltransferase 5 gene, involved in type 1 Lewis antigen synthesis, and show that the LTR promoter is most active in the gastrointe

Relative neurotoxin gene expression in clostridium botulinum type B, determined using quantitative reverse transcription-PCR.

A quantitative reverse transcription-PCR (qRT-PCR) method was developed to monitor the relative expression of the type B botulinum neurotoxin (BoNT/B) gene (cntB) in Clostridium botulinum. The levels of cntB mRNA in five type B strains were accurately monitored by using primers specific for cntB and for the reference gene encoding the 16S rRNA. The patterns and relative expression of cntB were dif

Full-length HERV-H elements with env SU open reading frames in the human genome

Human endogenous retroviruses (HERVs) are estimated to represent at least 1% of the human genome. An HERV-H env SU sequence (HERV-H19) was used to screen the high-throughput (htgs) and nonredundant (nr) databases for other HERV-H SU open reading frames (ORFs) and thus possible functional proteins. Using PCR with primers derived from HERV-H19 SU, we also obtained several new sequences with ORFs fro

Nanosecond to Microsecond Protein Dynamics Probed by Magnetic Relaxation Dispersion of Buried Water Molecules

Large-scale protein conformational motions on nanosecond – microsecond time scales are important for many biological processes, but remain largely unexplored because of methodological limitations. NMR relaxation methods can access these time scales if protein tumbling is prevented, but the isotropy required for high-resolution solution NMR is then lost. However, if the immobilized protein molecule

Biomolecular hydration: from water dynamics to hydrodynamics.

Thermally driven rotational and translational diffusion of proteins and other biomolecules is governed by frictional coupling to their solvent environment. Prediction of this coupling from biomolecular structures is a longstanding biophysical problem, which cannot be solved without knowledge of water dynamics in an interfacial region comparable to the dry protein in volume. Efficient algorithms ha

Cell intrinsic alterations underlie hematopoietic stem cell aging

Loss of immune function and an increased incidence of myeloid leukemia are two of the most clinically significant consequences of aging of the hematopoietic system. To better understand the mechanisms underlying hematopoietic aging, we evaluated the cell intrinsic functional and molecular properties of highly purified long-term hematopoietic stem cells (LT-HSCs) from young and old mice. We found t

Utbildnings utbplan kandidat ky2 old

– 254 – Utbildningsplan 1 Identifikation • Programmets namn och inriktning: kyrkomusikerutbildning. • Omfattning i högskolepoäng: 180 hp. • Nivå: G. • Programkod: KGKYM. • Utbildningsplanen är beslutad i Konstnärliga fakultetsstyrelsen den 12 november 2007. Utbild­ ningsplanen träder i kraft den 1 juli 2007. 2 Programbeskrivning Högre kyrkomusikerutbildning syftar till att utbilda musiker med god

https://www.mhm.lu.se/sites/mhm.lu.se/files/utbildnings_utbplan_kandidat_ky2_old.pdf - 2026-05-30

Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia

Distinct morphologic and clinical features associated with specific chromosomal abnormalities have been described in subgroups of myelodysplastic syndromes (MDS), which often are losses or gains and only rarely translocations. Among 103 consecutive MDS patients diagnosed and karyotyped at the Albert-Ludwigs University of Freiburg (ALU) between 1993 and 1999, two chronic myelomonocytic leukemias (C

Riktlinjer fu reviderade 151014

Riktlinjer FU reviderade_151014   Ins t i tu t ionen   fö r     serv ice  management  och   t jäns teve tenskap               RIKTLINJER FÖR FORSKARUTBILDNING I TJÄNSTEVETENSKAP Revidering fastställd av styrelsen för service management och tjänstevetenskap den 14 oktober 2015. Dnr STYR 2015/1162 De första doktoranderna i tjänstevetenskap antogs våren 2006. Vår ambition vid institutionen för servic

https://www.ses.lu.se/sites/ses.lu.se/files/riktlinjer_fu_reviderade_151014.pdf - 2026-05-30