Sökresultat

This paper presents the results of an explorative study on the strategies and tactics applied by the mechanical designer during the later phases of the design process. The method chosen for this study is experiment-based, which is appropriate for an in-depth examination of the designer's activities. Six experiments have been run based on three dimensions: 1) the carrying out of basic design tasks

New Information Systems Development Methodologies (ISDMs) are suggested in the belief that their deployment would be beneficial to consultants in their work. A large number of ISDMs already exist but their value has been questioned and at the same time new methodologies continue to be introduced in an attempt to support and improve the practice of information systems development work. What is not

An OH-functional polyester has been acrylated via transesterification of ethyl acrylate, catalyzed by Candida antarctica lipase B (CalB) in two different preparations: Novozym(R) 435 and immobilized on Accurel(R) MP1000. The batch process resulted in incomplete acrylation as well as severe degradation of the polyester. A high degree of acrylation was achieved by optimization through the applicatio

This research presents the modeling of the anaerobic digestion of cane-molasses vinasse, hereby extending the Anaerobic Digestion Model No. 1 with sulfate reduction for a very high strength and sulfate rich wastewater. Based on a sensitivity analysis, four parameters of the original ADM1 and all sulfate reduction parameters were calibrated. Although some deviations were observed between model pred

Non-linearity in the energy response of a Si p-i-n charged particle detector has been studied for incident particles with Z(1) between 3 and 26, and energies between 0.1 and 0.7 MeV per nucleon. Although the data closely followed a straight line relations, fitting of the data to a third order polynomial revealed that the response exhibited a persistent curvature that acted to reduce the energy int

The growing complexity of integrated circuits and increasing component density place higher requirements for raw material and clean room standards, which demand significant amounts of energy. In spite of these developments, semiconductor facilities managed to reduce their energy intensity measured per product unit. At the same time, the impact of increasing circuit integration on upstream life cyc

Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe (PIONEER) is a European network of excellence for big data in prostate cancer, consisting of 32 private and public stakeholders from 9 countries across Europe. Launched by the Innovative Medicines Initiative 2 and part of the Big Data for Better Outcomes Programme (BD4BO), the overarching goal of PIONEER is

Background: Lower urinary tract symptoms due to benign prostate enlargement (LUTS/BPE) can lead to significant disturbances to health-related quality of life (HRQoL) and psychological well-being. The aim of this study was to evaluate the effect of pharmacological treatment of LUTS/BPE on disease specific and generic QOL measures. Methods: Evolution was a European prospective, multicenter multi-nat

Objectives: To evaluate how surgeon heterogeneity – the variation in outcomes between individual surgeons – influences functional and oncological outcomes after robot-assisted laparoscopic prostatectomy (RALP) and retropubic radical prostatectomy (RRP), and to assess whether surgeon heterogeneity affects the comparison between RALP and RRP. Patients and Methods: Laparoscopic Prostatectomy Robot Op

Background: To use the European Association of Urology Research Foundation (EAURF) registry data to determine the proportion of contemporary Lower Urinary Tract Symptoms associated with Benign Prostatic Enlargement (LUTS/BPE) patients prescribed phytotherapy, and to determine their subjective quality of life and clinical progression responses. Methods: This was a prospective multicenter multinatio

Purpose: Differences exist concerning when and how to perform lymph node dissection (LND) during radical prostatectomy due to lack of high-grade evidence to its safety and efficacy. We aimed to compare readmission rates between limited and extended LND during open radical prostatectomy (ORP) and robot-assisted radical prostatectomy (RARP). Materials and methods: We conducted a prospective trial of

Anaplastic thyroid cancer (ATC) is one of the most malignant tumors, with a median survival of only a few months. The tumorigenic processes of this disease have not yet been completely unraveled. Here, we report an mRNA expression and DNA methylation analysis of fourteen primary ATCs. ATCs clustered separately from normal thyroid tissue in unsupervised analyses, both by RNA expression and by DNA m

Near-field focusing (NFF) is a fundamental enabler for a broad spectrum of applications utilizing large intelligent surfaces (LIS) within sub-10 GHz frequency bands. This paper investigates the impact of element pattern on NFF properties, when the LIS array is a large planar array. The NFF properties of maximum received power, focal width, and focal depth are analyzed for three typical antenna pat

We consider the averaging process on an infinite connected graph with bounded degree and independent, identically distributed starting values or initial opinions. Assuming that the law of the initial opinion of a vertex has a finite second moment, we show that the opinions of all vertices converge in L2 to the first moment of the law of the initial opinions. A key tool in the proof is the Sharing

This paper proposes a D-band patch antenna featuring four parasitic elements and a loaded superstrate layer. Inspired by a previous parasitic patch antenna design, the new structure is synthesized from scratch using characteristic mode analysis. The new design features different operating principles that enable low-cost single-layer fabrication on PCB HDI technology, while retaining wideband opera

Climatic feedbacks and ecosystem impacts related to dust in the Arctic include direct radiative forcing (absorption and scattering), indirect radiative forcing (via clouds and cryosphere), semi-direct effects of dust on meteorological parameters, effects on atmospheric chemistry, as well as impacts on terrestrial, marine, freshwater, and cryospheric ecosystems. This review discusses our recent und

We have prepared electrodes for photo-electro-chemical cells which have enabled to pre-charge colloidal quantum dots in well-controlled fashion. Femtosecond transient absorption measurements were carried out revealing clear speed-up of the photo-induced charge carrier dynamics, particularly the recombination. Such studies allow to understand the behavior of light harvesting materials in operationa

Background: The longevity for people with intellectual disability (ID) has significantly increased in developed countries during the past decades. Consequently, the incidence of cancer is expected to increase in this group. The aim of the present study was to investigate the prescription of pain medication in older cancer patients with intellectual disability (ID) compared to older patients in the

The amount and quality of greenness in the local outdoor environment has repeatedly been linked to human well-being. Different types of green areas are likely required in order to meet the various needs of people throughout the course of their lives and with regard to individual social and economic living conditions. The aim of the present study was to increase the understanding of different pathw