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Critical time window of neuronal cholesterol synthesis during neurite outgrowth

Cholesterol is an essential membrane component enriched in plasma membranes, growth cones, and synapses. The brain normally synthesizes all cholesterol locally, but the contribution of individual cell types to brain cholesterol metabolism is unknown. To investigate whether cortical projection neurons in vivo essentially require cholesterol biosynthesis and which cell types support neurons, we have

Artificial intelligence and radiologists in prostate cancer detection on MRI (PI-CAI): an international, paired, non-inferiority, confirmatory study

Background: Artificial intelligence (AI) systems can potentially aid the diagnostic pathway of prostate cancer by alleviating the increasing workload, preventing overdiagnosis, and reducing the dependence on experienced radiologists. We aimed to investigate the performance of AI systems at detecting clinically significant prostate cancer on MRI in comparison with radiologists using the Prostate Im

European Obspack compilation of atmospheric carbon dioxide data from ICOS and non-ICOS European stations for the period 1972-2023; : obspack_co2_466_GLOBALVIEWplus_v8.0_2023-04-26

This data package contains high accuracy CO2 dry air mole fractions from 58 ICOS and non-ICOS European observatories at in total 132 observation levels, collected by the ICOS Atmosphere Thematic Centre (ATC) and provided by the station contributors. The package is part of the Globalviewplus v8.0 data product, released in 2022 and is intended for use in carbon cycle inverse modeling, model evaluati

Frequency-dependent community dynamics driven by sexual interactions

Research in community ecology has tended to focus on trophic interactions (e.g., predation, resource competition) as driving forces of community dynamics, and sexual interactions have often been overlooked. Here we discuss how sexual interactions can affect community dynamics, especially focusing on frequency-dependent dynamics of horizontal communities (i.e., communities of competing species in a

Forskningsetik 3hp, MEFFE02 (7)

Brevmall KURSPLAN Dnr U 2020/ 47 (1) Fastställd av FUN 2020-09-17, gäller från 2021-01-01 Forskningsetik, MEFFE02 Research Ethics 3 högskolepoäng Nivå F Allmänna uppgifter Vänder sig till forskarstuderande vid Medicinska fakulteten. Kursen går två veckor på heltid. Undervisningsspråk Svenska eller engelska Syfte Kursen syftar till att ge kunskaper i forskningsetik, inklusive god forskningssed och

https://www.intramed.lu.se/sites/intramed.lu.se/files/2023-02/Forskningsetik%203hp,%20MEFFE02%20(7).pdf - 2026-05-30

Kp edma42

Kursguide - Course Syllabus Fastställande Kursplanen är fastställd av Ledningsgruppen för kandidatprogrammet i Equality and Diversity Management 2013-01-15 och senast reviderad 2015-02-10. Den reviderade kursplanen gäller från och med 2015-03-01, vårterminen 2015. Allmänna uppgifter Kursen är en obligatorisk kurs inom kandidatprogrammet Equality and Diversity Management och ges under termin 4. Und

https://www.ses.lu.se/sites/ses.lu.se/files/kp_edma42.pdf - 2026-05-30

Kp edmb61 161108

Kursguide - Course Syllabus • • • Fastställande Kursplanen är fastställd av Ledningsgruppen för kandidatprogrammet i Equality and Diversity Management 2016-11-08 att gälla från och med 2017-01-10, vårterminen 2017. Allmänna uppgifter Kursen ingår i Kandidatprogramet equality and diversity management och ges sjätte terminen. Undervisningsspråk: Svenska Moment på engelska kan förekomma. Kursens mål

https://www.ses.lu.se/sites/ses.lu.se/files/kp_edmb61_161108.pdf - 2026-05-30

Kp edmc21 171115

Kursguide - Course Syllabus • • • • • Fastställande Kursplanen är fastställd av Ledningsgruppen för kandidatprogrammet i Equality and Diversity Management 2017-11-15 att gälla från och med 2018-01-10, vårterminen 2018. Allmänna uppgifter Kursen är en obligatorisk kurs inom Kandidatprogrammet equality and diversity management och ges termin två. Undervisningsspråk: Svenska Moment på engelska kan fö

https://www.ses.lu.se/sites/ses.lu.se/files/kp_edmc21_171115.pdf - 2026-05-30

DHP 1.13

Dokumenthanteringsplan VERSION 1.13 2023-06-12 Dokumenthanteringsplan version 1.13 tillhör Klassificeringsstruktur version 1.8 Lunds universitet dnr V 2023/1358 Gäller fr.o.m. 2023-06-12 Allmänt om dokumenthanteringsplanen Vilka specifika handlingstyper som får gallras och efter hur lång frist, framgår av följande sidor i denna dokumenthanteringsplan. Om inget annat anges börjar gallringsfristen l

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2023-06/DHP%201.13.pdf - 2026-05-30

The Ageing Population

The process of population ageing that has been occurring in Sweden can be expected to continue during the coming decades, the population pyramid will become increasingly rectangular, and possibly even demonstrating a shrinking base. This will lead to increasing challenges in terms of financing pensions, elderly care and healtcare. These problems will continue for at least 30 years with no demograp

Training Regions Research Centre Strategic Plan 2011-2013

Our world is changing and cities and regions are increasingly understood not only as places, but also as vital hubs in national and global networks, through which people, capital, goods and services flow to ensure the functioning of society, as we know it. People and capital are increasingly concentrated in these hubs, which aside of positive effects on efficiency also is associated with challenge

A study of the mechanical designer's strategies and tactics during the later phases of the engineering design process

This paper presents the results of an explorative study on the strategies and tactics applied by the mechanical designer during the later phases of the design process. The method chosen for this study is experiment-based, which is appropriate for an in-depth examination of the designer's activities. Six experiments have been run based on three dimensions: 1) the carrying out of basic design tasks

Designing societal safety: A study of the Swedish crisis management system

Design is an activity aimed at solving an unsolved problem or improving an existing solution. In the area of societal safety, there are many activities that could be classified as design activities. For example when different actors are implementing measures to mitigate certain risk scenarios or when they are considering actions that could improve their capability to respond to various crises. We

Exploring the Nature of Information Systems Development Methodology: A Synthesized View Based on a Literature Review

New Information Systems Development Methodologies (ISDMs) are suggested in the belief that their deployment would be beneficial to consultants in their work. A large number of ISDMs already exist but their value has been questioned and at the same time new methodologies continue to be introduced in an attempt to support and improve the practice of information systems development work. What is not

Understanding dependencies: Why safety, security and sustainability are increasingly challenging for cities and regions

Abstract in UndeterminedThe increasing effectiveness and efficiency of modern society is not only beneficial, but also liable for new or increased vulnerabilities. The seemingly ever-increasing complexity of modern society is in other words bringing new challenges for safety, security and sustainability. At the heart of these challenges lay an incremental increase in dependencies between sectors,

Biocatalytic polyester acrylation-process optimization and enzyme stability.

An OH-functional polyester has been acrylated via transesterification of ethyl acrylate, catalyzed by Candida antarctica lipase B (CalB) in two different preparations: Novozym(R) 435 and immobilized on Accurel(R) MP1000. The batch process resulted in incomplete acrylation as well as severe degradation of the polyester. A high degree of acrylation was achieved by optimization through the applicatio

Pathways to Health and Well-being

Adverse early-life conditions have lasting effects on old-age health and mortality (Almond, 2006, Barker, 1992, Barker, 1994, Mazumder et al., 2010 and Roseboom et al., 2006). Some have even considered reductions in early life disease exposure to be a primary driver of historical mortality declines (Finch and Crimmins, 2004). Consequently, understanding the mechanisms through which early and later