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Objective: Developmental programming alters growth and metabolic outcome in children born small for gestational age (SGA). We explored insulin and glucose metabolism in SGA children treated with a fixed GH dose over 1 year. Methods: In the North European Small for Gestational Age Study (NESGAS), 110 short SGA children received GH at 67 mu g/kg/day for 1 year. Insulin secretion was assessed by acut
Shibanqiao Reservoir (0.24 km(2)) and Xiaohe Reservoir (0.28 km(2)) have catchments of 6.00 km(2) and 22.69 km(2), respectively. They essentially represent "strongly eroded" (Shibanqiao) and "mildly eroded" (Xiaohe) regions in Guizhou Plateau, southwestern China. Sediment cores were retrieved from the two reservoirs and soils were also sampled from their catchments. Mineral magnetic measurements w
The doubly magic nucleus 100Sn represents a crucial test for the nuclear shell model, which is a widely used model for a quantitative description of nuclei. Excited states in 100Sn are experimentally not accessible with present day techniques, but it is possible to gain insight into its structure by studying the properties of excited states of neighboring nuclei. These nuclei
The aim of this study was to investigate from the perspective of formal carers the care given to people aged 65 and over, who are cared for in their own homes by informal care. Thirty-three district nurses (DNs) and 20 home service assistants in a municipality with 13500 inhabitants (over 65 years old), were interviewed about the location of care recipients and 398 care recipients were located. Mo
Background Ximelagatran is a novel, oral direct thrombin inhibitor under investigation as an alternative to warfarin for prevention of thromboembolism in patients with nonvalvular atrial fibrillation (AF). Two long-term studies in patients with AF and at least one additional risk factor for stroke are underway to compare the safety and efficacy of fixed-dose ximelagatran (36 mg bid) without coagu
IMPORTANCE: Prostate-specific antigen (PSA) screening has potential to reduce prostate cancer mortality but frequently detects prostate cancer that is not clinically important.OBJECTIVE: To describe rates of low-grade (grade group 1) and high-grade (grade groups 2-5) prostate cancer identified among men invited to participate in a prostate cancer screening protocol consisting of a PSA test, a 4-ka
Background: Current systemic therapies for metastatic pancreatic ductal adenocarcinoma are associated with poor outcomes with a 5-year overall survival rate under 5%. We aimed to assess the safety and antitumour activity of mitazalimab, a human CD40 agonistic IgG1 antibody, with modified FOLFIRINOX (mFOLFIRINOX; fluorouracil, leucovorin, oxaliplatin, and irinotecan), in chemotherapy-naive patients
This thesis examines the transmission mechanism of indexed bonds and loans in comparison to nominal bonds in the context of Iceland's monetary policy. The study analyses the effectiveness of indexed bonds and loans in transmitting monetary policy, in the form of the policy rate, and their impact on the economy by using a VAR model. The study explores the historical background of indexation in
Technical assistance to public sector organisations is a much-debated topic and showcases a considerable size in contemporary international development assistance. Yet, the empirical evidence base on which factors contribute to the outcomes of projects within this field is surprisingly slim and diffuse. Particularly, the mechanisms through which different factors affect project outcomes remains un
Background and purpose: During radiotherapy, rectal cancer patients show inter-fractional internal motion that effects the delivered dose distribution. The purpose of this work is to study I) the inter-fractional bladder volume change, II) the effect of bladder volume change on bowel dose distribution, III) the effect of bladder optimization on the relationship between bladder volume and bowel dos
Background and aim: The Barsebäck nuclear power plant (NPP) units ceased operations in 1999 and 2005. Now the NPP is in the phase of decommissioning, which is a complicated process that will take many years to complete. Radiological characterization of the surrounding area is a part of the decommissioning process. The aim of this thesis was to identify and quantify residual anthropogenic radioacti
Entreprenadavtal avser i allmänhet omfattande och långvariga arbeten som inbegriper flera olika parter. Det är relativt vanligt förekommande att parterna har olika åsikt gällande hur ett specifikt avtalsvillkor ska tolkas. Det finns ingen entreprenadrättslig lagstiftning. Företrädare för BKK, Byggandets Kontraktskommitté, har framförhandlat standardkontrakt. Standardkontrakten har en stark ställniConstruction contracts generally refer to extensive and long-term projects involving several different parties. It is relatively common for the parties to have different opinions regarding how a specific contractual term should be interpreted. There is no construction contract law in the area. Hereby representatives of the BKK, the Construction Contracts Committee, have negotiated standard contrac
De provokativa åtgärderna är en polisiär arbets- och utredningsmetod, vilken traditionellt beskrivs som att polisen i sitt brottsbekämpande arbete lockar fram beteenden från en enskild brottsmisstänkt, i form av yttranden eller handlingar, som kan vara ofördelaktiga för vederbörande. De provokativa åtgärderna har använts inom den polisiära verksamheten en längre tid, trots avsaknad av lagregleringProvocative measures can be described as a an investigation method, whereas the police entices to behaviour through expressions or actions, which in some aspect are unfavourable or disadvantegous for the provoced person. Provocative measures have been used as an investigation method by the Swedish police for a longer time, even though no legislation legitimizes or regulates its usage. The uncertai
Previous scholarship has viewed the productive activities of fans—otherwise known as fan labor—as a means to successfully permeate an otherwise cluttered social media environment. The following study challenges as well as problematizes these existing assumptions by exploring: (i) fan perceptions of the ‘work’ they perform; and (ii) the distinct forms the performed ‘work’ assume, specifically in re
Given the calls to examine accelerators across different regions and contexts, we ask the research question: How do accelerators adapt to institutional, social, and spatial constraints of emerging and established ecosystems? With this research question, we conduct qualitative research to understand how two different accelerators, one located in Skåne, Sweden and another located in Dhaka, Banglades
Examensarbetets titel: Kapitalisering av operationell leasing - hur påverkar den föreslagna förändringen av IAS 17 små och medelstora företag på Stockholmsbörsen? Seminariedatum: 2015-01-15. Kurs: FEKH69, Examensarbete i redovisning på kandidatnivå, 15 högskolepoäng. Författare: Joel Holmdahl, Klaudia Wojtkowiak och Mergime Preteni. Handledare: Niklas Sandell. Nyckelord: IAS 17, kapitalisering, Mi
BACKGROUND: HYPO-RT-PC is a phase 3 trial comparing ultra-hypofractionated and conventionally fractionated radiotherapy in intermediate-to-high-risk localised prostate cancer. This 10-year update reports long-term efficacy and toxicity outcomes.METHODS: In this open-label, randomised, phase 3, non-inferiority trial done in ten centres in Sweden and two in Denmark, we recruited men aged 75 years or
Obesity is a key contributor to heart failure, driving increased morbidity, mortality, and healthcare costs. This association is supported by multiple pathophysiological mechanisms and consistent epidemiological evidence, particularly not only in heart failure with preserved ejection fraction (HFpEF), but also in heart failure with reduced ejection fraction (HFrEF). Given the rising prevalence of
Korruption utgör ett allvarligt hot mot rättssäkerhet, ekonomisk utveckling och förtroendet för offentliga institutioner. Samtidigt är skiljeförfarandet en vanlig tvistlösningsmetod inom de branscher som är mest exponerade för korruption. Mutor och korruption har stått i centrum i flera uppmärksammade skiljeförfaranden, vilket väcker frågor om sådana tvister överhuvudtaget lämpar sig för prövning Corruption poses a serious threat to the rule of law, economic development and public trust in government institutions. At the same time, arbitration is a common method of commercial dispute resolution in the business sectors most exposed to corruption. Bribery and corruption have been central issues in several high-profile arbitration proceedings, raising concerns as to whether such disputes are
