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A statistical framework to define multivariable subgroups in complex population-based datasets Read the full paper here.
https://www.lupop.lu.se/article/numero - 2025-12-20
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Is Who you Ask Important?
Concordance Between Survey and Registry Data on Medication Use Among Self- and Proxy-Respondents in the Longitudinal Study of Aging Danish Twins and the Danish 1905-Cohort Study Read the full paper here.
https://www.lupop.lu.se/article/who-you-ask-important - 2025-12-20
Prostate cancer in Asia
Design of a patient registry to inform real-world treatments, outcomes, and quality of life Read the full paper here.
https://www.lupop.lu.se/article/prostate-cancer-asia - 2025-12-20
Using a Web-Based Data Collection Platform to Implement an Effective Electronic Patient-Reported Outcome Registry
Routine patient-reported outcome measure (PROM) collection often disrupts clinical workflow and can place a burden on both the patient and the provider. Electronic PROM collection systems, if implemented deliberately to maximize convenience and efficiency, have the potential to mitigate these obstacles. Read the full paper here.
De-identified linkage of data across separate registers
A proposal for improved protection of personal information in registry-based clinical research Read more here.
https://www.lupop.lu.se/article/de-identified-linkage-data-across-separate-registers - 2025-12-20
The Australasian Pelvic Floor Procedure Registry: Not before time
The objective of the registry is to improve the health out-comes of the tens of thousands of women who undergo pelvic floor reconstructive procedures each year. Read the full paper here.
https://www.lupop.lu.se/article/australasian-pelvic-floor-procedure-registry-not-time - 2025-12-20
Period-specific mean annual hospital volume of radical cystectomy is associated with outcome and perioperative quality of care: a nationwide population-based study
The current study supports centralisation of RC for bladder cancer, but also underpins the need for monitoring treatment delays associated with referral New publication in BJU International.Read more here
A paradigm shift in studies based on rheumatoid arthritis clinical registries
Clinical research is the study of aspects of patient health or illness that are closely related to clinical practice. In the late 20th and early 21th century, outcomes for patients with rheumatoid arthritis (RA) improved dramatically due to breakthroughs in new drugs. Patient-reported outcome measures now play a significant role in the drug development process as study endpoints in clinical trials
https://www.lupop.lu.se/article/paradigm-shift-studies-based-rheumatoid-arthritis-clinical-registries - 2025-12-20
Censoring for Loss to Follow-up in Time-to-event Analyses of Composite Outcomes or in the Presence of Competing Risks
The least biased censoring strategy for time-to-event analyses in the presence of LTFU depends on the event and estimand of interest. New publication in Epidemiology.Read more here.
Common Pitfalls of Head and Neck Research Using Cancer Registries
Pitfalls were identified in 2 major areas—design and data analysis. Design pitfalls included unbalanced cohorts, uncontrolled covariates, and flawed oncologic variables. Analytical pitfalls included incorrect application of univariate analyses, inclusion of inaccurate data, and inclusion of stage IVc disease in curative survival analysis. Additional limitations of database studies were identified,
https://www.lupop.lu.se/article/common-pitfalls-head-and-neck-research-using-cancer-registries - 2025-12-20
Joint comorbidities among Swedish carriers of haemophilia: A register‐based cohort study over 22 years
Carriers of haemophilia suffer a significant risk for joint comorbidities. This risk seems to correlate to the factor activity. Our findings underline the impor‐tance of regular clinical follow‐up of carriers at HTCs. New publication in Wiley.Read more here.
A registry-based study evaluating overall survival and treatment duration in Swedish patients with metastatic castration-resistant prostate cancer treated with enzalutamide
Enzalutamide can be used to effectively treat mCRPC patients in daily clinical settings, despite the patients being older and less healthy than those enrolled in the previous randomised, clinical registration studies. Read the full paper here.
Manipulation under anesthesia after primary knee arthroplasty in Sweden
Incidence, patient characteristics and risk of revision Read the full paper here.
https://www.lupop.lu.se/article/manipulation-under-anesthesia-after-primary-knee-arthroplasty-sweden - 2025-12-20
The use of anthropometric measures in the prediction of incident gout
Results from a Swedish community-based cohort study Read the full paper here.
https://www.lupop.lu.se/article/use-anthropometric-measures-prediction-incident-gout - 2025-12-20
High exposure to perfluorinated compounds in drinking water and thyroid disease
A cohort study from Ronneby, Sweden Read the full paper here.
https://www.lupop.lu.se/article/high-exposure-perfluorinated-compounds-drinking-water-and-thyroid-disease - 2025-12-20
Cross comparison and prognostic assessment of breast cancer multigene signatures in a large population-based contemporary clinical series
The current study supports the usage of gene expression signatures in specific clinical treatment groups within population-based breast cancer. It also stresses the need of further development to reach higher consensus in individual patient classifications, especially for intermediate-risk patients, and the targeting of patients where current gene signatures and prognostic variables provide little
Unlocking the Potential of Population-Based Cancer Registries
This article describes how central cancer registries can provide a population-based sample frame that will lead to studies with strong external validity, how central cancer registries can link with public and private health insurance claims to obtain complete treatment information, how central cancer registries can use informatics techniques to provide population-based rapid case ascertainment, ho
https://www.lupop.lu.se/article/unlocking-potential-population-based-cancer-registries - 2025-12-20
Population‐based, nationwide registration ofprostatectomies in Sweden
Report on a nationwide, population‐based register with transparent reporting of data on the performance of radical prostatectomy. These data are needed as a basis for quality assurance with comparisons of results from individual surgeons and hospitals. Read the full paper here.
https://www.lupop.lu.se/article/population-based-nationwide-registration-ofprostatectomies-sweden - 2025-12-20
Validating registry data on statins prescriptions by bloodmeasurements
This study showed a high adherence with treatment with statins among colorectal cancer patients. Read the full paper here.
https://www.lupop.lu.se/article/validating-registry-data-statins-prescriptions-bloodmeasurements - 2025-12-20
Methods to generate and validate a Pregnancy Register in theUK Clinical Practice Research Datalink primary care database
The Pregnancy Register offers huge research potential because of its large size, high completeness, and availability. Further validation work is underway to enhance this data resource and identify optimal approaches for its use. Read the full paper here.