The responses of 56 neurons recorded in the lumbosacral spinal cord of halothane-anesthetized rats were studied following the application of mechanical stimuli to the skin on the lateral aspect of the paw or electrical stimulation of the sural nerve. Only neurons driven by A- and C-fiber stimulation were considered. The evoked activity in a nerve supplying flexor muscles, the common peroneal nerve

It is not clear where analgesic measures such as morphine and acupuncture have their sites of action. Since analgesia from acupuncturelike stimulation is reversed by naloxone (Sjolund and Eriksson, Brain Res. 173:295, 1979) it is probably mediated via endorphins. The two analgesic procedures mentioned may thus use similar inhibitory mechanisms. We now present data from autoradiographic measurement

Nociceptive C fiber input to SI in the halothane-nitrous oxide anesthetized rat was assessed by recording cortical field potentials evoked by noxious thermal cutaneous stimulation with CO2-laser pulses. Morphine topically applied onto the lumbar spinal cord produced a dose-dependent inhibition of nociceptive C fiber input from the hind paw to the contralateral SI. The inhibitory effect of morphine

Aim: It has been claimed that supraspinal structures are necessary forthe depression of nocifensive behaviour elicited by acupuncture or acupuncturelike (AL) stimulation. However, nocifensive reflexes in the spinal catwere inhibited for long periods by a mechanism releasing opieids on AL conditioning stimulation of groups II-III muscle afferents (Sj~lund and Eriksson, Neurosci.Lett. S3:264:1979).

Recent experimental studies suggest that the nociceptive withdrawal reflex system essentially has a "modular" organization, with each module concerned with the control of a single or a small group of muscles. This organizational principle appears to apply also to some spinoolivocerebellar pathways.

It is now well documented that the cerebellar cortex is divided into sagittal zones which can be identified by their climbing fibre inputs from specific regions of the inferior olive. Each cortical zone sends its efferent fibres, the Purkinje cell axons, to a separate group of neurones in the cerebellar or vestibular nuclei (Oscarsson, 1980, Voogd and Bigare, 1980, Voogd, 1982, Trott and Armstrong

Denna forskningsrapport sammanfattar resultaten från en studie bedriven inom ramen för Pilotverksamheten för bedömning av reell kompetens (REKO) under ledning av Universitets- och Högskolerådet (UHR). I studien utvecklas:• en generisk valideringsmodell för bedömning av reell kompetens för tillgodoräknande som högskoleutbildning. Valideringsmodellen (av både summativ och formativ karaktär) ska kunn

Summary and conclusions. On the spinal and supraspinal outputs from the superficial dorsal horn.

The fracture toughness of a polymer-metal laminate composite is obtained by mechanical testing of a specimen containing a pre-crack. The laminate is a material used for packaging. It consists of a thin aluminium foil and a polymer coating. A centre cracked panel test geometry is used. Each of the layers forming the laminate is also tested separately. The result is compared with the measured fractuThe fracture toughness of a polymer-metal laminate composite is obtained by mechanical testing of a specimen containing a pre-crack. The laminate is a material used for packaging. It consists of a thin aluminium foil and a polymer coating. A centre cracked panel test geometry is used. Each of the layers forming the laminate is also tested separately. The result is compared with the measured fractu

Stress intensity factors are calculated for long plane cracks with one tip interacting with a region of graded material characteristics. The material outside the region is considered to be homogeneous. The analysis is based on assumed small differences in stiffness in the entire body. The linear extent of the body is assumed to be large compared with that of the graded region. The crack tip, incluStress intensity factors are calculated for long plane cracks with one tip interacting with a region of graded material characteristics. The material outside the region is considered to be homogeneous. The analysis is based on assumed small differences in stiffness in the entire body. The linear extent of the body is assumed to be large compared with that of the graded region. The crack tip, inclu

Bi-materials composed of thin layers ideally bonded to large substrates are considered. Cracksemerging from an almost flat surface and propagating through the bi-materials are studied.The cracks acquire realistic geometrical shapes, where the tips are integral parts of the cracksurfaces. Crack propagation is related to surface evolution resulting from material loss due tocorrosion. Controlling mecBi-materials composed of thin layers ideally bonded to large substrates are considered. Cracks emerging from an almost flat surface and propagating through the bi-materials are studied. The cracks acquire realistic geometrical shapes, where the tips are integral parts of the crack surfaces. Crack propagation is related to surface evolution resulting from material loss due to corrosion. Controlling