Many factors can ultimately lead to an increased blood pressure and it is a generally accepted view that an increase in the active tension of arterioles reflects an increase of the free calcium concentration in the cytosol of the vascular smooth muscle cells. Only recently, however, has the possibility been considered that blood pressure regulation could be influenced by calcium homeostasis. A bac

A Swedish translation of the Barrow Neurological Institute Screen for Higher Cerebral Functions was administered to 52 normal control subjects and 36 patients with well-documented brain dysfunction. Findings replicated those reported in American samples. Level of performance was strikingly similar between Swedish controls and American controls, especially in individuals between 15 and 39 years. Sw

Popular Abstract in Swedish Aktie- och fondsparandet bland allmänheten har ökat dramatiskt i Sverige under 1990-talet, och allt fler företag har valt börsintroducering som finansieringsform. På så sätt har frågor som rör värdepappersmarknaden fått en ökad och mer allmän relevans, inte minst när det gäller regleringen av vad som är tillåtet och otillåtet att göra på marknaden. Både från statligt håIn this dissertation the Swedish Financial Supervisory Authority's (FSA) investigation of suspected insider trading offences is examined and analysed. The aim of the study is to describe FSA's investigative activity in insider cases during the 1990?s, a period of both increased activity on the Swedish stock market as well as changed regulation. The study places the investigation of insider offence

Intrapartum death has become a rare event since the introduction of electronic fetal monitoring (EFM). Randomized studies of EFM versus intermittent auscultation show that EFM reduces the risk of low Apgar score at birth and of neonatal seizures, although it may be possible to ensure low perinatal mortality even with intermittent auscultation alone. The rate of operative deliveries may increase wi

Introduction: Vertebral fracture is a strong risk factor for future spine and hip fractures; yet recent data suggest that only 5-20% of subjects with a spine fracture are identified in primary care. We aimed to develop easily applicable algorithms predicting a high risk of future spine fracture in men and women over 50 years of age. Methods: Data was analysed from 5,561 men and women aged 50+ year

Chiral bifunctional oxabicyclodecanediones (keto lactones) were synthesized from the corresponding bicyclo[3.3.1]nonane diones 1-5 by employing a regioselective Baeyer-Villiger oxidation. Enantiomers with high enantiomeric excess were obtained by chiral HPLC enantiomer separation on microcrystalline, triacetylcellulose column. Circular dichroism spectra of molecules containing two chromophores, na

The expected distributions of eclipse-depth versus period for eclipsing binaries of different luminosities are derived from large-scale population synthesis experiments. Using the rapid Hurley et al. BSE binary evolution code, we have evolved several hundred million binaries, starting from various simple input distributions of masses and orbit-sizes. Eclipse probabilities and predicted distributio

Mechanical force is generated within skeletal muscle cells by contraction of specialized myofibrillar proteins. This paper explores how the contractile force generated at the sarcomeres within an individual muscle fiber is transferred through the connective tissue to move the bones. The initial key point for transfer of the contractile force is the muscle cell membrane (sarcolemma) where force is

Objectives: The aim of the present study was to analyze the effect of systemic administration of nicotine on bone healing in osseous defects in the tibia of rabbits. Materials and methods: Sixteen female rabbits received nicotine (n=8; test group) or saline (n=8; control group) via subcutaneously placed mini-osmotic pumps for 8 weeks. The animals underwent three surgical operations during the expe

Occurrences of fire ignitions in a given region during a specified period of time are modelled as outcomes of a Poisson point process. The ignition frequency is considered a function of the total floor area of the building. Parameter estimates and their uncertainties are computed. Different criteria for model selection are used. The proposed methodology is specifically useful in the case with smal

The aim of this study was to assess the frequency and prognostic value of TP53 gene somatic mutations in non-small cell lung cancer. The study group included 240 NSCLC patients who underwent pulmonary resection at the Department of Thoracic Surgery, Medical University of Gdansk. Tumour samples were evaluated for the presence of TP53 gene mutations in exons 5-8. In 157 cases SSCP method was used as

Popular Abstract in Swedish Denna avhandling handlar om en grupp narkotikamissbrukare som gjort självmordsförsök. Såväl självmord som självmordsförsök är betydligt vanligare bland narkotikamissbrukare jämfört med totalbefolkningen. Bland vårdade narkotikamissbrukare är det mellan 19 till 47 procent som gjort självmordsförsök. Det höga självmordsförsökstalet bland narkotikamissbrukare förklaras oftThe aim of this thesis is to describe suicide attempts in a group of drug abusers who previously had received treatment of their addiction. Another aim is to interpret and analyse the life situations that the individual associates with the suicide attempt. The dissertation is based on interviews conducted on two occasions with 92 drug abusers, 62 men and 30 women. The majority of the drug abusers

Housing of animals in an enriched environment (EE) has many positive effects on brain structure and function and can facilitate recovery from various brain injuries. The purpose of this study was to evaluate whether enriched rearing could alter the stress response induced by repeated immune challenge and to investigate the influence of EE and immune challenge on glutamate receptor gene expression

Objective: To investigate the associations between psychosocial conditions at work, social capital/social participation, and daily smoking. Design/setting/participants/measurements: The 2000 public health survey in Scania is a cross sectional postal questionnaire study with a 59% participation rate. A total of 5180 persons aged 18–64 years that belonged to the work force and the unemployed were i