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The major challenges faced by confectionery supply chain are lack of information, traceability, managing the ownership of goods across supply chains, inability to track vendors in real-time. Blockchain and Internet of Things (IoT) in Industry 4.0 era help organisations to overcome these challenges by guaranteeing authentic information, real-time visibility, and transparency across the supply chain
Shelley King and John B. Pierce’s edition of The Romance of the Forest (1791) brings Ann Radcliffe’s (1764–1823) novel to new life. The editors’ introduction is paired with well selected source documents contemporaneous with the influential Gothic romance. My favourite example (not included by King and Pierce) for the Romantic-era writers’ admiration for Radcliffe’s aesthetics is John Keats’s lett
First published in The New Yorker magazine as a short story in January 2016, “1 = 1” addresses profound questions about what it means to swim in a large lake as a human and a non-human, terrestrial animal. The elliptic short story captures the central female character’s struggle with the rough waves of the lake during her morning swim and her subsequent observations as the ekphrastic commentator o
Ralsgård & Tullberg – DIALOGUERalsgård & Tullberg Release Fourth Album: DIALOGUESwedish wooden flute duo Ralsgård & Tullberg are releasing their fourth album, DIALOGUE – a return to their roots and a celebration of musical conversation.For over two decades, Andreas Ralsgård and Markus Tullberg have been prominent voices on the Swedish folk music scene. Known for their innovative use of
Audiobooks are more popular than ever before. The article examines how this so-called “audiobook boom”, as well as the communities, reading practices, and economic systems surrounding audiobooks affect how we ascribe value to books and reading. The article departs from a notion of literary values based in the sociology of literature. While its contribution is primarily conceptual, the discussion iAudiobooks are more popular than ever before. The article examines how this so-called “audiobook boom”, as well as the communities, reading practices, and economic systems surrounding audiobooks affect how we ascribe value to books and reading. The article departs from a notion of literary values based in the sociology of literature. While its contribution is primarily conceptual, the discussion i
The Islamic Republic of Iran (IRI) has employed assassinations and proxy violence as tools of statecraft. Dissidents in exile have been killed, targeted, or systematically threatened, while Israeli-linked entities across Europe have faced repeated attacks. In recent years, Tehran has increasingly outsourced these operations to state-linked criminal intermediaries. This paper analyzes Iran’s approa
The involvement of the extracellular matrix (ECM) in tumor progression has motivated the development of biomaterials mimicking the tumor ECM to develop more predictive cancer models. Particularly, polypeptides based on elastin could be an interesting approach to mimic the ECM due to their tunable properties. Here, we demonstrated that elastin-like recombinamer (ELR) hydrogels can be suitable bioma
Perceiving and understanding human motion is a fundamental problem in computer vision, with diverse applications encompassing sports analytics, healthcare monitoring, entertainment, and intelligent interactive systems. Multi-camera systems, by capturing multiple viewpoints simultaneously, enable robust tracking and reconstruction of human poses in 3D, overcoming limitations of single-view approach
This Review discusses the use of elastin-like polymers and their recombinant version, elastin-like recombinamers, in drug-delivery systems. These macromolecules exhibit a number of interesting properties that are rarely found together in any other family of materials, especially extremely high biocompatibility, high bioactivity and functionality, complex yet fully controlled composition, and stimu
The field of biomedicine is constantly investing significant research efforts in order to gain a more in-depth understanding of the mechanisms that govern the function of body compartments and to develop creative solutions for the repair and regeneration of damaged tissues. The main overall goal is to develop relatively simple systems that are able to mimic naturally occurring constructs and can t
BACKGROUND: Drug delivery systems that are able to control the release of bioactive molecules and designed to carry drugs to target sites are of particular interest for tissue therapy. Moreover, systems comprising materials that can respond to environmental stimuli and promote self-assembly and higher order supramolecular organization are especially useful in the biomedical field. Objetive: This r
In the last decades, recombinant structural proteins have become very promising in addressing different issues such as the lack of traceability of biomedical devices or the design of more sensitive biosensors. Among them, we find elastin-like recombinamers (ELRs), which can be designed to self-assemble into diverse structures, such as hydrogels. Furthermore, they might be combined with other prote
The morbidity of bone fractures and defects is steadily increasing due to changes in the age pyramid. As such, novel biomaterials that are able to promote the healing and regeneration of injured bones are needed to overcome the limitations of auto-, allo-, and xenografts, while providing a ready-to-use product that may help to minimize surgical invasiveness and duration. In this regard, recombinan
Over the last decades, novel therapeutic tools for osteochondral regeneration have arisen from the combination of mesenchymal stromal cells (MSCs) and highly specialized smart biomaterials, such as hydrogel-forming elastin-like recombinamers (ELRs), which could serve as cell-carriers. Herein, we evaluate the delivery of xenogeneic human MSCs (hMSCs) within an injectable ELR-based hydrogel carrier
