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Neuroblastoma (NB) is a highly heterogeneous childhood cancer where the presence of chemotherapy resistant cancer stem cells (CSCs) contributes to a high relapse rate in high-risk patients. Understanding the mechanisms by which CSCs contribute to therapy resistance could lead to future treatment strategies. The human pseudokinase TRIB3 has been shown to support stemness and play a role in cell cyc

Transposable elements (TE) are parasitic genetic entities that have the ability to alter their position within a genome and have the potential to influence its functionality. Although TEs play beneficial roles in the evolution of their host, they are active in various human disorders including neurological diseases, where may contribute to the progress of the disease. Long Interspersed Nuclear Ele

Due to a rising concern for the climate, more industries are becoming controversial due to their greenhouse gas intensive production. This study has looked into one of these industries, the agricultural industry in Denmark, and the controversy surrounding this industry. By adopting a critical discourse analysis (CDA) perspective, this study investigates the discursive construction of (de)legitimat

I Malmö byggs tidigare industriområden nu om till nya kvarter med bostäder, kontor, skolor och butiker – så kallad blandad stadsbebyggelse. Ett område som pekats ut för en liknande utveckling framöver är det fortfarande verksamma industriområdet Emilstorp. Vid det här projektets början hade jag aldrig varit i Emilstorp utan istället alltid promenerat eller cyklat runt det, utan att reflektera överFormer industrial areas in Malmö are currently being redeveloped into a so-called mixed-use city with housing, offices, schools and shopping. One area which has been chosen for a similar development is the still active industrial area Emilstorp. At the start of this project, I had never been to Emilstorp but instead always walked or cycled around it without reflecting on its existence. When I now

The aim of this essay is to analyze and compare three books’ children and adult editions, in an attempt to enable a discussion about the book publishing companies marketing strategies of the separate target audiences. The literature chosen is Harry Potter and the prisoner of Azkaban, The Chronicles of Narnia (The Lion, the Witch and the Wardrobe and the collection book), and Insurgent, part two of

För att lösa dagens bostadsbrist utan att det sker på bekostnad av värdefull mark, satsar en övervägande del av de svenska kommunerna på förtätning. Den främsta fördelen med att bygga tätt är att det optimerar förutsättningarna för variation i serviceutbudet och leder till ett effektivare utnyttjande av infrastrukturen. Dock påstår många att nya bostäder i samband med förtätning skulle ge värdesänIn order to solve housing shortage while preserving valuable land, a majority of the Swedish municipalities are implementing densification as a planning strategy. Denser development provides better support for a variety of services and optimizes public transportation. Despite the several benefits, infill development is commonly claimed to lower nearby housing prices. Studies on whether new residen

Forskningsfråga: Hur upplever enhetschefer respektive stödfunktioner i Kommunen tillit i sin organisation idag? Syfte: Syftet med studien är att öka förståelsen för hur anställda i offentlig verksamhet upplever tillit inför införandet av tillitsbaserad styrning. Vidare åsyftas att göra en jämförelse av vad tillit innebär för enhetschefer och stödfunktioner. Studiens övergripande syfte blir därResearch question: How do unit managers and support functions within the studied municipality interpret trust in their organisation today? Purpose: The purpose of this study is to increase the understanding of how employees in the public sector experience trust prior to the introduction to trust-based governance. Furthermore, it is intended to make a comparison of what trust means for unit mana

This thesis investigates principal terms that are pertinent specifically to the visual character of architecture. In common terminology such as order, complexity, variation, monotony, and contrast. By surveying recent public debates it is deduced that both laymen and professionals lack the sufficient language to establish common ground. By a doctor-patient metaphor it follows that no remedy can be

I västvärlden använder vi dagligen plastprodukter och det är svårt att föreställa sig en tillvaro utan plast, som idag är oumbärliga över ett brett spektrum av applikationer. Resulterande problem inkluderar nedskräpning, mikroplaster och global uppvärmning som ett direkt resultat av den fossila råvaran, som dessutom inte är en förnybar resurs. Nya typer av material som kan ersätta den fossila plasFossil-based resources for plastic production is growingly being challenged by renewable material in applications such as wood-plastic composites. One company dedicated to contribute to this transition is Bio Fiber Tech AB (BFT) who have patented a novel treatment of the wood component for improved compatibility with the polymer matrix. This thesis was in collaboration with BFT with the aim to cha

Bland rävar och igelkottar. Ibsen, Strindberg och det moderna dramat som kunskapshistoria (Among Foxes and Hedgehogs: Ibsen, Strindberg, and Modern Drama as History of Knowledge) is an exploration of modern drama as it relates to one of main features of modernity – specialization. The thesis is meant to function as a pilot study for a larger research project wherein the twofold aim is i) to shed l

Examensarbetets titel: “Att offras eller att inte offras”. En kvalitativ intervjustudie som undersöker konsumenters uppfattning av scapegoating i form av VD:ns avgång i samband med en kris och dess påverkan på varumärken Seminariedatum: 2021-02-06 Kurs: FEKH29, Examensarbete kandidatnivå i marknadsföring, 15 högskolepoäng Författare: Anna Sahlberg Carlsson, Beatrice Molin, Casper Tönning Handl

Anthropogenic climate change has increased the frequency of extreme drought events and leads to “hotter” droughts. Topography controls plant available water and site-specific climatic conditions. Drought sensitivity may therefore vary over short distances between wet and dry locations of the landscape. However, topography is rarely included as a factor in research investigating vegetation dynamics

From a managerial perspective, organizational effectiveness, whether internal or external, is of extreme importance. Therefore, management studies should investigate which phenomena need to be emphasized and safeguarded to utilize organizational effectiveness. Intra-organizational trust and job satisfaction are both defined as phenomena that are of influence on organizational effectiveness. This s

I takt med ökad efterfrågan av digitala tjänster har IT-sektorn växt fram som en ny energiintensiv industri. Ett område där digitaliseringen fått fotfäste är inom finansiell teknologi, där digitala valutor och betalningsnätverk erbjuder stora möjligheter. Precis som internet har möjliggjort för datorer över hela världen att kommunicera på en gemensam plattform, vill det amerikanska företaget StellThe colossal electricity consumption of proof-of-work cryptocurrencies such as Bitcoin and Ethereum has caused critical examination of how consensus in blockchain-solutions is designed. Stellar is a decentralized, open-membership payment network built on blockchain technology, with the goal of enabling money to flow between banks, businesses and people across the global financial infrastructure, w

Robust optimization plays a vital role in proton therapy treatment planning. A monoenergetic beam of protons has a finite range and delivers most of its dose at some specific depth in the patient. This allows the design of treatments that mainly damage the tumor and not any surrounding tissue. However, this property also makes proton therapy sensitive to uncertainties in the patient model used for

Examensarbetets titel: Duktiga flickors bekännelser: En analys av kvinnors upplevelser av stereotypa förväntningar kopplade till könsrollen och chefsrollen. Seminariedatum: 2 juni 2021 Kurs: FEKH49, Examensarbete i organisation på kandidatnivå, 15 hp Författare: Molly Backman, Hanna Elmteg, Lone Engholm Handledare: Nadja Sörgärde Fem nyckelord: Könsroll, chefsroll, double bind, Role Congruity TheoTitle: Confessions of a Good Girl: An Analysis of Women’s Experiences of the Stereotypical Expectations on the Gender Role and the Managerial Role. Seminar date: June 2nd 2021 Course: FEKH49, Business Administration: Bachelor’s Degree Project in Organization, Undergraduate level, 15 credits Authors: Molly Backman, Hanna Elmteg, Lone Engholm Supervisor: Nadja Sörgärde Five Keywords: Gender role, ma

Industry 4.0 can be described as the next generation-factories that is characterised by putting a high demand for automation and flexible production lines. The proposed way to achieve this goal is through a large number of Industrial IoT devices(IIoT) in the factory, some having high availability- and low-latency requirements. This demands for a software that can monitor and manage the application

Using data spanning from 1910 to 2020, house price dynamics of Stockholm and Gothenburg are found to be significantly affected by income, household debt, interest rates, construction costs and immigration. Real house prices in Stockholm and Gothenburg exhibit debt elasticities of 1.34 and 1.12, noticeably greater than their respective income elasticities of 0.24 and 0.39. Real house prices in both

The goal of the thesis is to simulate the Ericsson Many-Core Architecture, EMCA, and implement a dynamic scheduler for the system using reinforcement learning methods. The system contains shared resources that receive and complete jobs. Also, the deadlines and latency definitions can change depending on the job type. The scheduler should aim to avoid missing deadlines as well as aim to reduce the

Jag har alltid älskat att vandra i naturen och under de senaste åren, inte minst under år 2020, har jag lagt märke till att fler och fler börjat tillbringa tid ute i skog och mark. Det senaste årets reserestriktioner och uppmaningar till att hålla fysisk distans har bidragit till att människor ersatt sina utlandssemestrar med upplevelser här hemma i Sverige och vandringstrenden har ökat något enor