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In vivo imaging of leukocyte-endothelium interactions in septic lung injury

Excessive accumulation of leukocytes in the lung represents a key feature in the development of an acute lung injury (ALI). Numerous studies demonstrated that leukocyte rolling is a compulsory precondition for the firm adhesion in organs. However, it seems that the recruitment process of leukocytes in the lung is more complex. Increasing evidence suggests that recruitment of leukocytes in pulmonar

How can rAAV-α-synuclein and the fibril α-synuclein models advance our understanding of Parkinson's disease?

Abstract: Animal models of Parkinson's disease (PD) are important for understanding the mechanisms of the disease and can contribute to developing and validating novel therapeutics. Ideally, these models should replicate the cardinal features of PD, such as progressive neurodegeneration of catecholaminergic neurons and motor defects. Many current PD models emphasize pathological forms of α-synucle

China Desalination Cost Compared to Global Long-Term Estimation

The future overall trends of desalination cost are estimated using least-square fitting method based on Excel, and four major impact factors, named technology, feed water, energy sources and capacity, are discussed and prospected. Five different types of desalination technology are presented and bench-marked for long-term use. RO and MSF are dominant technologies. Six different input water sources

Knowledge hoarding : antecedent or consequent of negative acts? The mediating role of trust and justice

Purpose – The purpose of this paper is to investigate whether and how knowledge hoarding, functions as antecedent and consequent of work related negative acts, as a measure of bullying. The authors investigate the relation as mediated by trust and justice. Design/methodology/approach – Data stem from a longitudinal study in which questionnaire responses were collected twice from 1,650 employees in

War Violence, Sexual War Violence and Victimhood in Reconciliation Narratives of Survivors from the War in Bosnia and Herzegovina

In this analysis of the retold experiences of 27 survivors of the war in northwestern Bosnia, the aim is to describe the informants’ portrayal of “war violence”, “sexual war violence”, “victimhood”, and “reconciliation” as a social phenomenon as well as analyzing the discursive patterns that contribute to constructing the category “victim” and “perpetrator”. The violence practice during the war is

Digital breast tomosynthesis (3D-mammography) screening : A pictorial review of screen-detected cancers and false recalls attributed to tomosynthesis in prospective screening trials

This pictorial review highlights cancers detected only at tomosynthesis screening and screens falsely recalled in the course of breast tomosynthesis screening, illustrating both true-positive (TP) and false-positive (FP) detection attributed to tomosynthesis. Images and descriptive data were used to characterise cases of screen-detection with tomosynthesis, sourced from prospective screening trial

Modeling of mass and charge transport in a solid oxide fuel cell anode structure by a 3D lattice Boltzmann approach

A 3D model at microscale by the lattice Boltzmann method (LBM) is proposed for part of an anode of a solid oxide fuel cell (SOFC) to analyze the interaction between the transport and reaction processes and structural parameters. The equations of charge, momentum, heat and mass transport are simulated in the model. The modeling geometry is created with randomly placed spheres to resemble the part o

SOFC modeling at the cell scale including hydrogen and carbon monoxide as electrochemically active fuels

Fuel cells are promising for future energy systems, because they are energy efficient and able to use renewable fuels. A fully coupled computational fluid dynamics (CFD) approach based on the finite element method (with the software COMSOL Multiphysics) in two-dimensions is developed to describe an intermediate temperature solid oxide fuel cell (SOFC) single cell. Governing equations covering heat

Measurement of inclusive two-particle angular correlations in pp collisions with the ATLAS detector at the LHC

We present a measurement of two-particle angular correlations in proton-proton collisions at root s = 900 GeV and 7 TeV. The collision events were collected during 2009 and 2010 with the ATLAS detector at the Large Hadron Collider using a single-arm minimum bias trigger. Correlations are measured for charged particles produced in the kinematic range of transverse momentum p(T) > 100 MeV and pseudo

Search for Higgs and Z Boson Decays to J/psi gamma and Upsilon(nS)gamma with the ATLAS Detector

A search for the decays of the Higgs and Z bosons to J/psi gamma and Upsilon(nS)gamma (n = 1,2,3) is performed with pp collision data samples corresponding to integrated luminosities of up to 20.3 fb(-1) collected at root s = 8 TeV with the ATLAS detector at the CERN Large Hadron Collider. No significant excess of events is observed above expected backgrounds and 95% C.L. upper limits are placed o

Online teaching going massive: input and outcomes

The proliferation of massive open online courses is a recent phenomenon in higher education. At the International Institute for Industrial Environmental Economics at Lund University in Sweden, emerging pedagogical approaches in e-learning have long been embraced, allowing for valuable experience with new educational technologies applied in education for sustainability. In 2014, the Institute was g

Pituitary dysfunction after aneurysmal subarachnoid hemorrhage is associated with impaired early outcome

Objective Poor outcome and neuropsychological sequelae after aneurysmal subarachnoid hemorrhage (SAH) is a persistent problem. Pituitary dysfunction has been proposed as a contributing factor. Clinical studies have given variable and conflicting results on its importance and incidence after SAH. The aim of this study was to prospectively examine SAH patients with assessment of endocrine function i

Navigating Information Overload Caused by Automated Testing – A Clustering Approach in Multi-Branch Development

Background. Test automation is a widely used technique to increase the efficiency of software testing. However, executing more test cases increases the effort required to analyze test results. At Qlik, automated tests run nightly for up to 20 development branches, each containing thousands of test cases, resulting in information overload. Aim. We therefore develop a tool that supports the analysis

Using remote sensing to model carbon source/sink dynamics in the sahel

Recent research has identified the grasslands of the Sahel as a potential carbon sink, but regional carbon stock accounting in such biomes is undermined by the poorly recognized role they play in the carbon cycle as well as lack of data. In this paper, we demonstrate the feasibility of coupling the satellite data-driven light use efficiency model (Lund University Light Use Efficiency Model - LULUE

A comparison between the microflora of Herrgård cheese from three different dairies

The microflora of Herrgård cheese produced at three dairies was grouped by phenotypical key tests and typed by randomly amplified polymorphic DNA (RAPD). Ten cheeses from the same vat at each dairy were analysed, five after 3 and another five after 6 months of ripening. All cheeses were organoleptically graded as Herrgård after uniform national standards, and only small but characteristic differen

Neural networks, multitemporal landsat thematic mapper data and topographic data to classify forest damages in the Czech republic

This study uses multitemporal Landsat Thematic Mapper data and topographic data for the purpose of classifying coniferous forest damage in the Czech Republic using an artificial neural network. Comparing the neural network-based classification with earlier studies and a multinominal logistic regression using identical training and test data indicates that the back propagation algorithm is comparab

Heat transfer analysis of a traction machine with directly cooled laminated windings

A directly enhanced cooled winding in an electrical traction machine has the potential to extend the operation range, which is in particular attractive for a traction application when operating near peak power for extended periods of time. This paper presents the heat transfer analysis of a modular machine segment with a laminated winding. The laminated winding has a great potential when it comes