Determination of antibiotic residues in surface water by solid-phase extraction and high-performance liquid chromatography with UV/Vis detection
This work aimed to optimize a multiclass reverse-phase HPLC-DAD chromatographic method and SPE method for the quantification of eight antibiotics in wastewater. Cefalexin, Levofloxacin, Nitrofurantoin, Doxycycline, Nalidixic Acid, Oxacillin sodium salt, and Cloxacillin sodium salt were separated with a C6-Phenyl (100 x 2 mm, 3.00 μm particle size) column within 10 minutes. Gradient elution was per