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Structural dynamics in liquid water slow down dramatically in the supercooled regime. To shed further light on the origin of this super-Arrhenius temperature dependence, we report high-precision (17)O and (2)H NMR relaxation data for H(2)O and D(2)O, respectively, down to 37 K below the equilibrium freezing point. With the aid of molecular dynamics (MD) simulations, we provide a detailed analysis
Interleukin-19 (IL-19) is a putative Th2, anti-inflammatory interleukin. Its expression and potential role in atherogenesis are unknown. IL-19 is not detected in normal artery and is expressed to a greater degree in plaque from symptomatic versus asymptomatic patients, suggesting a compensatory counter-regulatory function. We tested whether IL-19 could reduce atherosclerosis in susceptible mice an
Ongoing global warming not only involves changes in temperature and the global mean; it affects more or less every part of the climate. Regional temperature changes are often greater or smaller than corresponding changes in the global mean. In some cases the direction of change may also be different. For example, temperature changes are higher over land than over the ocean. Precipitation increases
In the absence of early B-cell factor 1 (EBF1), B-cell development is arrested at an uncommitted progenitor stage that exhibits increased lineage potentials. Previously, we investigated the roles of EBF1 and its DNA-binding partner Runx1 by evaluating B lymphopoiesis in single (EBF1(het) and Runx1(het)) and compound haploinsufficent (Ebf1(+/-) Runx1(+/-), ERhet) mice. Here, we demonstrate that dec
To ascertain the epigenomic features, i.e., the methylation, non-coding RNA, and gene expression patterns, associated with gain of i(12p) in Pallister-Killian syndrome (PKS), we investigated single cell clones, harboring either disomy 12 or tetrasomy 12p, from a patient with PKS. The i(12p)-positive cells displayed a characteristic expression and methylation signature. Of all the genes on 12p, 13%
Commentators interested in school-based prevention programs point to the importance of economic issues for the future of prevention efforts. Many of the processes and aims of prevention science are dependent upon prevention resources. Although economic analysis is an essential tool for assessing resource use, the attention given economic analysis within school-based prevention remains cursory. Lar
The outcomes of the Fourth Session of the Global Platform for Disaster Risk Reduction show that making cities and rural areas safe from disasters and climate change impacts and enhancing citizens' resilience is everybody's business and part of the larger sustainability challenge. Under the theme Resilient People, Resilient Planet', the session took place on 19-23 May 2013 in Geneva, Switzerland. T
This discussion highlights and defines key factors and organisational structures for the transformation of local agro-biomass based bioenery systems in Sweden and Denmark. Cross case study analysis is applied to 13 examples where straw is used for energy at various scales within a conceptual framework developed by the authors. This also delivers a cross-country comparison of systems and of the sta
This study explores gender, activity, and well-being among people with mental illness attending day centers in Sweden. Based on survey data of 215 attendees, this study applies the concepts of doing gender and regulatory regimes to analyze the relationship between being involved in gendered activities and wellbeing. The results show that while both male and female participants are involved in gend
Aim: To develop a logistic regression model for discrimination between benign and malignant unilocular solid cysts with papillary projections but no other solid components, and to compare its diagnostic performance with that of subjective evaluation of ultrasound findings (subjective assessment), CA 125 and the risk of malignancy index (RMI). Methods: Among the 3511 adnexal masses in the Interna
A bacterium that could completely metabolize phenol in batch culture supplied with up to 1200mg phenoll(-1) at room temperature (25 degrees C) was isolated from the activated sludge of the industrial wastewater treatment plant of a Coke company (Cairo, Egypt). Morphological and physiological characterization showed strain TW1 was a motile, strictly aerobic, gram negative and short-rod occurring si
What has caused the early 21st-century emissions explosion in China? Driving a global explosion, it appears to stand in some relation to processes of globalization, but these links have mostly remained unexplored. This article revisits some established frameworks for understanding the connection between globalization and environmental degradation and argues that they are insufficient for explainin
This work develops a scattering and an inverse scattering theory for the Sturm-Liouville equation u '' qu = lambda wu where w may change sign but q >= 0. Thus the left-hand side of the equation gives rise to a positive quadratic form and one is led to a left-definite spectral problem. The crucial ingredient of the approach is a generalized transform built on the Jost solutions of the problem and h
Abstract in UndeterminedThis study are focused on the deformation zones occurring in the work piece in a machining process and the corresponding cutting forces. The fully coupled thermo-mechanical FE-model for orthogonal cutting, developed in [1] is utilized. The work piece material is modeled with Johnson-Cook plasticity including damage formulation. Simulations for different feed depths were per
To evaluate the natural history of untreated complete or partial scapholunate (SL) ligament tears associated with displaced distal radius fractures.
We present the multibunch tracking code mbtrack developed to simulate, in 6-dimensional phase space, single- and multibunch collective instabilities driven by short- and long-range wakefields in storage rings. Multiple bunches, each composed of a large number of macroparticles, are tracked, allowing simulation of both intra- and interbunch motions. Besides analytical impedance models, the code all
Targeted measurements of low abundance proteins in complex mixtures are in high demanded in many areas, not the least in clinical applications measuring biomarkers. We here present the novel platform AFFIRM (AFFInity sRM) that utilizes the power of antibody fragments (scFv) to efficiently enrich for target proteins from a complex background and the exquisite specificity of an SRM-MS based detectio
Background: Stress ulcer prophylaxis (SUP) may decrease the incidence of gastrointestinal bleeding in patients in the intensive care unit (ICU), but the risk of infection may be increased. In this study, we aimed to describe SUP practices in adult ICUs. We hypothesised that patient selection for SUP varies both within and between countries. MethodsAdult ICUs were invited to participate in the surv
